公开(公告)号：US3876501A

公开(公告)日：1975-04-08

申请号：US36111973

申请日：1973-05-17

Applicant: BAXTER LABORATORIES INC

Inventor： HANUSHEWSKY MICHAEL

IPC: C12N11/12 ,  A61K38/00 ,  A61K38/46 ,  A61K39/385 ,  A61K39/44 ,  C08B31/00 ,  C08B37/00 ,  C12N11/10 ,  C07G7/02

CPC classification number: C08B31/00 ,  C08B37/00 ,  C12N11/10 ,  Y10S530/813

Abstract: Water-soluble carbohydrates can be activated by means of cyanogen bromide in a nonaqueous medium to exhibit an improved level of binding reactivity toward enzymes and other proteins, while preventing cross-linking and consequent water-insolubility in the carbohydrates.