公开(公告)号：US20180186725A1

公开(公告)日：2018-07-05

申请号：US15577393

申请日：2016-05-27

Applicant: BASF SE

Inventor： Thomas SCHAUB ,  Joan GALLARDO DONAIRE ,  Martin ERNST

IPC: C07C209/26 ,  C07D265/30 ,  C07D317/58 ,  C07F17/02 ,  B01J31/24 ,  B01J31/22

CPC classification number: C07C209/26 ,  B01J31/185 ,  B01J31/20 ,  B01J31/2295 ,  B01J31/2409 ,  B01J31/2414 ,  B01J31/2433 ,  B01J2231/4283 ,  B01J2231/44 ,  B01J2231/643 ,  B01J2531/821 ,  C07B2200/07 ,  C07C213/02 ,  C07C2602/08 ,  C07D265/30 ,  C07D317/58 ,  C07F17/02 ,  C07C211/27 ,  C07C211/29 ,  C07C217/58 ,  C07C211/30 ,  C07C211/42 ,  C07C211/03

Abstract: The present invention relates to a method for the reductive amination of a carbonyl compound, comprising one or more carbonyl groups amenable to reductive amination, forming the corresponding primary amine, characterized in that the reaction is carried out in the presence of a homogeneously dissolved catalyst complex K, comprising at least one metal atom from Group 8, 9 or 10 of the periodic table, bearing a bidentate phosphane ligand, a carbonyl ligand, a neutral ligand and a hydride ligand, and also an acid as co-catalyst.