公开(公告)号：US20160348082A1

公开(公告)日：2016-12-01

申请号：US15116669

申请日：2015-02-02

Applicant: BASF SE

Inventor： Joanna Martyna Krawczyk ,  Stefan Haefner ,  Hartwig Schröder ,  Esther Dantas Costa ,  Oakar Zelder ,  Gregory von Abendroth ,  Christoph Wittmann ,  René Stellmacher ,  Judith Becker ,  Anna Lange ,  Benjamin J. Lyons ,  Thomas J. Lyons ,  Eudes De Crecy ,  Ewa Hughes

IPC: C12N9/12 ,  C12P7/46

CPC classification number: C12N9/1205 ,  C12N15/52 ,  C12P7/46 ,  C12Y207/0104

Abstract: The present invention relates to a modified microorganism having, compared to its wild-type, a reduced activity of the enzyme that is encoded by the pykA-gene. The present invention also relates to a method for producing an organic compound and to the use of modified microorganisms.

Abstract translation: 本发明涉及与其野生型相比具有由pykA基因编码的酶的活性降低的修饰微生物。 本发明还涉及一种生产有机化合物的方法和使用改性微生物。