专利检索 ap:("Axys Pharmaceuticals, Inc.") AND inv:"Aleksandr Kolesnikov" 第 1 页

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发明申请
2- [5- (5-carbamimidoyl-1H-heteroaryl)-6-hydroxybiphenyl-3-yl]-succinic acid derivatives as factor viia inhibitors 审中-公开
标题翻译： 2- [5-（5-甲脒基-1H-杂芳基）-6-羟基联苯-3-基] - 琥珀酸衍生物作为因子viia抑制剂

公开(公告)号：US20030114457A1

公开(公告)日：2003-06-19

申请号：US10190147

申请日：2002-07-03

申请人： Axys Pharmaceuticals, Inc.

发明人： Huiyong Hu , John Hendrix , Aleksandr Kolesnikov , Roopa Rai , William Dvorak Shrader , David Sperandio , Wendy Young , Steve Torkelson

IPC分类号： A61K031/53 , A61K031/519 , A61K031/52 , A61K031/502

CPC分类号： C07D471/04 , C07C69/738 , C07C205/56 , C07D209/18 , C07D235/18

摘要： The present invention relates to novel inhibitors of Factors VIIa, IXa, Xa, XIa, in particular Factor VIIa, pharmaceutical compositions comprising these inhibitors, and methods for using these inhibitors for treating or preventing thromboembolic disorders. Processes for preparing these inhibitors are also disclosed.

摘要翻译： 本发明涉及因子VIIa，IXa，Xa，XIa，特别是因子VIIa的新型抑制剂，包含这些抑制剂的药物组合物，以及使用这些抑制剂治疗或预防血栓栓塞性疾病的方法。还公开了制备这些抑制剂的方法。