公开(公告)号：US20200165347A1

公开(公告)日：2020-05-28

申请号：US16625902

申请日：2018-06-29

申请人： Aslan Pharmaceuticals PTE LTD ,  CSL LIMITED

发明人： Bertil Lindmark ,  Ann Gee Lisa Ooi

IPC分类号： C07K16/28 ,  A61P35/00

摘要： The present disclosure provides a method of treating cutaneous T cell lymphoma (CTCL), in particular mycosis fungoides and/or Sézary syndrome, comprising administering a therapeutically effective amount of an antagonist antibody or binding fragment thereof specific to the IL-13 receptor to a patient in need thereof.

公开(公告)号：US20190151326A1

公开(公告)日：2019-05-23

申请号：US16252452

申请日：2019-01-18

申请人： Aslan Pharmaceuticals Pte. Ltd.

发明人： Bertil Lindmark ,  Ann Gee Lisa Ooi

IPC分类号： A61K31/5377 ,  A61P35/02 ,  A61K31/517 ,  A61K31/4545 ,  A61K31/075 ,  A61K31/502 ,  A61K31/201 ,  A61K31/4745

摘要： A method of treating haematological cancer with a therapy comprising a DHODH inhibitor. Also provided is a combination therapy comprising a pan-HER inhibitor and a DHODH inhibitor for treating a haematological cancer.

公开(公告)号：US11382903B2

公开(公告)日：2022-07-12

申请号：US16154422

申请日：2018-10-08

申请人： Aslan Pharmaceuticals Pte. Ltd.

发明人： Bertil Lindmark ,  Ann Gee Lisa Ooi ,  Mark Thomas McHale

IPC分类号： A61K31/4418 ,  A61P35/02 ,  A61K31/505 ,  A61K45/06 ,  A61K31/075 ,  A61K31/4545 ,  A61K31/502 ,  A61K31/517 ,  A61K31/553

摘要： A method of treating haematological cancer with a therapy comprising a DHODH inhibitor. Also provided is a combination therapy comprising a pan-HER inhibitor and a DHODH inhibitor for treating a haematological cancer.

公开(公告)号：US11311548B2

公开(公告)日：2022-04-26

申请号：US16252452

申请日：2019-01-18

申请人： Aslan Pharmaceuticals Pte. Ltd.

发明人： Bertil Lindmark ,  Ann Gee Lisa Ooi ,  Mark Thomas McHale

IPC分类号： A61K31/5377 ,  A61P35/02 ,  A61K31/517 ,  A61K31/4545 ,  A61K31/075 ,  A61K31/201 ,  A61K31/4745 ,  A61K31/502 ,  A61K31/704 ,  A61K31/164 ,  A61K31/4995

摘要： A method of treating haematological cancer with a therapy comprising a DHODH inhibitor. Also provided is a combination therapy comprising a pan-HER inhibitor and a DHODH inhibitor for treating a haematological cancer.

公开(公告)号：US20190038610A1

公开(公告)日：2019-02-07

申请号：US16154422

申请日：2018-10-08

申请人： Aslan Pharmaceuticals Pte. Ltd.

发明人： Bertil Lindmark ,  Ann Gee Lisa Ooi

IPC分类号： A61K31/4418 ,  A61P35/02

摘要： A method of treating haematological cancer with a therapy comprising a DHODH inhibitor. Also provided is a combination therapy comprising a pan-HER inhibitor and a DHODH inhibitor for treating a haematological cancer.