Cosmetic Use Of Geranylgeranyl-2-Propanol
    1.
    发明申请
    Cosmetic Use Of Geranylgeranyl-2-Propanol 有权
    香叶醇基-2-丙醇的化妆用途

    公开(公告)号:US20130058878A1

    公开(公告)日:2013-03-07

    申请号:US13639933

    申请日:2011-04-07

    CPC classification number: A61Q17/04 A61K8/342 A61Q19/08

    Abstract: Geranylgeranyl-2-propanol compound (GGP) having the following formula (I) is proposed for use according to the present invention as a cosmetic active compound for the prevention and treatment of aging of skin and its appendages. The GGP has a protective action against oxidative stress and free radical, on telomeres and on mitochondria and its activity. In particular, GGP can be used for the treatment of wrinkles, fine lines and visible discontinuities of skin, for the treatment pigmentation disorders.

    Abstract translation: 提出具有下式(I)的香叶基香叶基-2-丙醇化合物(GGP)用作根据本发明用作预防和治疗皮肤老化及其附属物的化妆品活性化合物。 GGP具有抗氧化应激和自由基,端粒和线粒体及其活性的保护作用。 特别地,GGP可用于治疗皱纹,细纹和可见的皮肤不连续性,用于治疗色素沉着障碍。

    Cosmetic use of geranylgeranyl-2-propanol
    2.
    发明授权
    Cosmetic use of geranylgeranyl-2-propanol 有权
    香叶基香叶基-2-丙醇的化妆品使用

    公开(公告)号:US09126060B2

    公开(公告)日:2015-09-08

    申请号:US13639933

    申请日:2011-04-07

    CPC classification number: A61Q17/04 A61K8/342 A61Q19/08

    Abstract: Geranylgeranyl-2-propanol compound (GGP) having the following formula I: is proposed for use according to the present invention as a cosmetic active compound for the prevention and treatment of aging of skin and its appendages. The GGP has a protective action against oxidative stress and free radical, on telomeres and on mitochondria and its activity. In particular, GGP can be used for the treatment of wrinkles, fine lines and visible discontinuities of skin, for the treatment pigmentation disorders.

    Abstract translation: 提出具有下式I的香叶基香叶基-2-丙醇化合物(GGP):根据本发明用作预防和治疗皮肤老化及其附属物的化妆品活性化合物。 GGP具有抗氧化应激和自由基,端粒和线粒体及其活性的保护作用。 特别地,GGP可用于治疗皱纹,细纹和可见的皮肤不连续性,用于治疗色素沉着障碍。

    Lipo-phosphated or lipo-sulphated compound, compositions comprising it and topical uses thereof
    4.
    发明授权
    Lipo-phosphated or lipo-sulphated compound, compositions comprising it and topical uses thereof 有权
    脂磷酸酯化或脂肪硫酸化的化合物,包含它的组合物及其局部用途

    公开(公告)号:US08603498B2

    公开(公告)日:2013-12-10

    申请号:US13522663

    申请日:2011-01-17

    CPC classification number: A61K8/553 A61Q19/00 A61Q19/08 C07C305/06 C07F9/091

    Abstract: The compound according to the invention has the following developed formula IX: wherein: X=PO(OH)2; SO2(OH); PO(OH)(Xaa)m or SO2(Xaa)m; A=H; OH; NH2 or akyl (1-6C); n=1 to 4; Y=—CO—OR2; —CO—NR3R4; —O—CO—R2; —C═CR2; R2=an alkyl, aryl, aralkyl, acyl, sulfonyl, sugar or alkoxy chain of 1 to 24 carbon atoms, linear, branched or cyclic, with or without substitutions, saturated or not, hydroxylated or not, sulfurated or not; R5=OH, O-alk (1-6C), (Xaa)m, NH2 or NH-alkyl(1-6C); Xaa=peptide of m aminoacids Xaa with m from 1 to 10; The compound is preferably phosphated, obtained from malic acid and having the following developed formula: A cosmetic composition comprising the compound of the present invention can improve the general condition of the skin, for example hydration, lightening and mechanical properties.

    Abstract translation: 根据本发明的化合物具有以下开发的式IX:其中:X = PO(OH)2; SO2(OH); PO(OH)(Xaa)m或SO2(Xaa)m; A = H; 哦; NH2或烷基(1-6C); n = 1〜4; Y = -CO-OR2; -CO-NR3R4; -O-CO-R2; -C = CR2; R 2 =具有1至24个碳原子的烷基,芳基,芳烷基,酰基,磺酰基,糖或烷氧基链,具有或不具有或不具有羟基化或不饱和或不具有取代基,不具有或不具有取代基,不具有或不具有取代基, R5 = OH,O-烷基(1-6C),(Xaa)m,NH2或NH-烷基(1-6C); Xaa = m为1〜10的m个氨基酸Xaa的肽; 该化合物优选磷酸化,由苹果酸获得并具有以下显影的配方:包含本发明化合物的化妆品组合物可以改善皮肤的一般状况,例如水合,减轻和机械性能。

    Lipo-Phosphated or Lipo-Sulphated Compound, Compositions Comprising It and Topical Uses Thereof
    5.
    发明申请
    Lipo-Phosphated or Lipo-Sulphated Compound, Compositions Comprising It and Topical Uses Thereof 有权
    脂肪磷酸盐或脂肪硫酸盐化合物,组合物及其主要用途

    公开(公告)号:US20130004439A1

    公开(公告)日:2013-01-03

    申请号:US13522663

    申请日:2011-01-17

    CPC classification number: A61K8/553 A61Q19/00 A61Q19/08 C07C305/06 C07F9/091

    Abstract: The compound according to the invention has the following developed formula IX: wherein: X=PO(OH)2; SO2(OH); PO(OH)(Xaa)m or SO2(Xaa)m; A=H; OH; NH2 or akyl (1-6C); n=1 to 4; Y=—CO—OR2; —CO—NR3R4; —O—CO—R2; —C═CR2; R2=an alkyl, aryl, aralkyl, acyl, sulfonyl, sugar or alkoxy chain of 1 to 24 carbon atoms, linear, branched or cyclic, with or without substitutions, saturated or not, hydroxylated or not, sulfurated or not; R5=OH, O-alk (1-6C), (Xaa)m, NH2 or NH-alkyl(1-6C); Xaa=peptide of m aminoacids Xaa with m from 1 to 10; The compound is preferably phosphated, obtained from malic acid and having the following developed formula: A cosmetic composition comprising the compound of the present invention can improve the general condition of the skin, for example hydration, lightening and mechanical properties.

    Abstract translation: 根据本发明的化合物具有以下开发的式IX:其中:X = PO(OH)2; SO2(OH); PO(OH)(Xaa)m或SO2(Xaa)m; A = H; 哦; NH2或烷基(1-6C); n = 1〜4; Y = -CO-OR2; -CO-NR3R4; -O-CO-R2; -C = CR2; R 2 =具有1至24个碳原子的烷基,芳基,芳烷基,酰基,磺酰基,糖或烷氧基链,具有或不具有或不具有羟基化或不饱和或不具有取代基,不具有或不具有取代基,不具有或不具有取代基, R5 = OH,O-烷基(1-6C),(Xaa)m,NH2或NH-烷基(1-6C); Xaa = m为1〜10的m个氨基酸Xaa的肽; 该化合物优选磷酸化,由苹果酸获得并具有以下显影的配方:包含本发明化合物的化妆品组合物可以改善皮肤的一般状况,例如水合,减轻和机械性能。

    COSMETIC COMPOSITIONS COMPRISING ORIDONIN AND NEW COSMETIC USES
    9.
    发明申请
    COSMETIC COMPOSITIONS COMPRISING ORIDONIN AND NEW COSMETIC USES 有权
    包含ORIDONIN和新化妆品用途的化妆品组合物

    公开(公告)号:US20120028916A1

    公开(公告)日:2012-02-02

    申请号:US13264547

    申请日:2010-04-15

    CPC classification number: A61Q19/08 A61K8/347 A61K8/498 A61Q19/02

    Abstract: The present invention related to cosmetic compositions comprising oridonin and new cosmetic uses. Oridonin is used for fighting the signs of cutaneous aging and for slimming. A composition comprising a combination of oridonin and darutigenol or a derivative thereof, in particular darutoside, is disclosed together with the cosmetic use of such composition.

    Abstract translation: 本发明涉及包含oridonin和新化妆品用途的化妆品组合物。 Oridonin用于抗衰老和减肥的迹象。 本发明公开了组合物,其组合物包含奥曲肽和达鲁必醇或其衍生物,特别是darutoside的组合,以及该组合物的美容用途。

    DEVICE FOR MEASURING THE MECHANICAL PROPERTIES OF THE SKIN WITHOUT CONTACT WITH THE MEASUREMENT ZONE
    10.
    发明申请
    DEVICE FOR MEASURING THE MECHANICAL PROPERTIES OF THE SKIN WITHOUT CONTACT WITH THE MEASUREMENT ZONE 审中-公开
    用于测量皮肤机械性能的设备,不与测量区域接触

    公开(公告)号:US20110092821A1

    公开(公告)日:2011-04-21

    申请号:US12736991

    申请日:2009-05-29

    CPC classification number: A61B5/0059 A61B5/0057 A61B5/442

    Abstract: The invention relates to a device for measuring the mechanical properties of the skin which is free from all parameters interfering with measurement. The device comprises: a) a pneumatic assembly (16) for delivering compressed air to apply a stress to the surface of the skin undergoing measurement, b) an electronic assembly (6) for contact-free measurements on said surface of the skin subjected to the stress, and c) a control software (19) for controlling the electronic assembly (6) and for processing measurement data in order to deduce the mechanical properties of the skin.

    Abstract translation: 本发明涉及一种用于测量皮肤的机械性能的装置,其不受干扰测量的所有参数的影响。 该装置包括:a)用于输送压缩空气以对经受测量的皮肤表面施加应力的气动组件(16),b)用于在所述皮肤的所述表面上进行无接触测量的电子组件(6),所述电子组件 应力,以及c)用于控制电子组件(6)并用于处理测量数据以便推断出皮肤的机械性能的控制软件(19)。

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