Abstract:
Geranylgeranyl-2-propanol compound (GGP) having the following formula (I) is proposed for use according to the present invention as a cosmetic active compound for the prevention and treatment of aging of skin and its appendages. The GGP has a protective action against oxidative stress and free radical, on telomeres and on mitochondria and its activity. In particular, GGP can be used for the treatment of wrinkles, fine lines and visible discontinuities of skin, for the treatment pigmentation disorders.
Abstract:
Geranylgeranyl-2-propanol compound (GGP) having the following formula I: is proposed for use according to the present invention as a cosmetic active compound for the prevention and treatment of aging of skin and its appendages. The GGP has a protective action against oxidative stress and free radical, on telomeres and on mitochondria and its activity. In particular, GGP can be used for the treatment of wrinkles, fine lines and visible discontinuities of skin, for the treatment pigmentation disorders.
Abstract:
The subject matter of the present invention is a cosmetic or dermopharmaceutic composition comprising a combination of homarine and erythritol as well as a non-therapeutic treatment method of the skin to improve cutaneous hydration, to prevent and/or treat cutaneous dryness signs, to restore and/or protect the cutaneous barrier function, to protect cells of the skin and/or of the scalp from osmotic shocks, for example from UV induced osmotic shocks.
Abstract:
The compound according to the invention has the following developed formula IX: wherein: X=PO(OH)2; SO2(OH); PO(OH)(Xaa)m or SO2(Xaa)m; A=H; OH; NH2 or akyl (1-6C); n=1 to 4; Y=—CO—OR2; —CO—NR3R4; —O—CO—R2; —C═CR2; R2=an alkyl, aryl, aralkyl, acyl, sulfonyl, sugar or alkoxy chain of 1 to 24 carbon atoms, linear, branched or cyclic, with or without substitutions, saturated or not, hydroxylated or not, sulfurated or not; R5=OH, O-alk (1-6C), (Xaa)m, NH2 or NH-alkyl(1-6C); Xaa=peptide of m aminoacids Xaa with m from 1 to 10; The compound is preferably phosphated, obtained from malic acid and having the following developed formula: A cosmetic composition comprising the compound of the present invention can improve the general condition of the skin, for example hydration, lightening and mechanical properties.
Abstract translation:根据本发明的化合物具有以下开发的式IX:其中:X = PO(OH)2; SO2(OH); PO(OH)(Xaa)m或SO2(Xaa)m; A = H; 哦; NH2或烷基(1-6C); n = 1〜4; Y = -CO-OR2; -CO-NR3R4; -O-CO-R2; -C = CR2; R 2 =具有1至24个碳原子的烷基,芳基,芳烷基,酰基,磺酰基,糖或烷氧基链,具有或不具有或不具有羟基化或不饱和或不具有取代基,不具有或不具有取代基,不具有或不具有取代基, R5 = OH,O-烷基(1-6C),(Xaa)m,NH2或NH-烷基(1-6C); Xaa = m为1〜10的m个氨基酸Xaa的肽; 该化合物优选磷酸化,由苹果酸获得并具有以下显影的配方:包含本发明化合物的化妆品组合物可以改善皮肤的一般状况,例如水合,减轻和机械性能。
Abstract:
The compound according to the invention has the following developed formula IX: wherein: X=PO(OH)2; SO2(OH); PO(OH)(Xaa)m or SO2(Xaa)m; A=H; OH; NH2 or akyl (1-6C); n=1 to 4; Y=—CO—OR2; —CO—NR3R4; —O—CO—R2; —C═CR2; R2=an alkyl, aryl, aralkyl, acyl, sulfonyl, sugar or alkoxy chain of 1 to 24 carbon atoms, linear, branched or cyclic, with or without substitutions, saturated or not, hydroxylated or not, sulfurated or not; R5=OH, O-alk (1-6C), (Xaa)m, NH2 or NH-alkyl(1-6C); Xaa=peptide of m aminoacids Xaa with m from 1 to 10; The compound is preferably phosphated, obtained from malic acid and having the following developed formula: A cosmetic composition comprising the compound of the present invention can improve the general condition of the skin, for example hydration, lightening and mechanical properties.
Abstract translation:根据本发明的化合物具有以下开发的式IX:其中:X = PO(OH)2; SO2(OH); PO(OH)(Xaa)m或SO2(Xaa)m; A = H; 哦; NH2或烷基(1-6C); n = 1〜4; Y = -CO-OR2; -CO-NR3R4; -O-CO-R2; -C = CR2; R 2 =具有1至24个碳原子的烷基,芳基,芳烷基,酰基,磺酰基,糖或烷氧基链,具有或不具有或不具有羟基化或不饱和或不具有取代基,不具有或不具有取代基,不具有或不具有取代基, R5 = OH,O-烷基(1-6C),(Xaa)m,NH2或NH-烷基(1-6C); Xaa = m为1〜10的m个氨基酸Xaa的肽; 该化合物优选磷酸化,由苹果酸获得并具有以下显影的配方:包含本发明化合物的化妆品组合物可以改善皮肤的一般状况,例如水合,减轻和机械性能。
Abstract:
The present invention concerns a peptide of following formula I: R being a side chain having at least one heteroatom selected from sulfur, nitrogen and oxygen in a carbonyl form (C═O); R1 being either H or a lipophilic chain; R2 being either OH or a lipophilic chain. More particularly the present invention concerns a cosmetic composition comprising a peptide as recited above and a physiologically acceptable medium. Results on the activity of the compounds are obtained and on the general state of the skin and its appendages, in particular via the stimulation of extracellular matrix components.
Abstract:
The subject matter of the present invention is a cosmetic or dermopharmaceutic composition comprising a combination of homarine and erythritol as well as a non-therapeutic treatment method of the skin to improve cutaneous hydration, to prevent and/or treat cutaneous dryness signs, to restore and/or protect the cutaneous barrier function, to protect cells of the skin and/or of the scalp from osmotic shocks, for example from UV induced osmotic shocks.
Abstract:
The present invention concerns a peptide of following formula I: R being a side chain having at least one heteroatom selected from sulfur, nitrogen and oxygen in a carbonyl form (C═O); R1 being either H or a lipophilic chain; R2 being either OH or a lipophilic chain. More particularly the present invention concerns a cosmetic composition comprising a peptide as recited above and a physiologically acceptable medium. Results on the activity of the compounds are obtained and on the general state of the skin and its appendages, in particular via the stimulation of extracellular matrix components.
Abstract:
The present invention related to cosmetic compositions comprising oridonin and new cosmetic uses. Oridonin is used for fighting the signs of cutaneous aging and for slimming. A composition comprising a combination of oridonin and darutigenol or a derivative thereof, in particular darutoside, is disclosed together with the cosmetic use of such composition.
Abstract:
The invention relates to a device for measuring the mechanical properties of the skin which is free from all parameters interfering with measurement. The device comprises: a) a pneumatic assembly (16) for delivering compressed air to apply a stress to the surface of the skin undergoing measurement, b) an electronic assembly (6) for contact-free measurements on said surface of the skin subjected to the stress, and c) a control software (19) for controlling the electronic assembly (6) and for processing measurement data in order to deduce the mechanical properties of the skin.