公开(公告)号：US08831703B2

公开(公告)日：2014-09-09

申请号：US11977153

申请日：2007-10-23

申请人： Andre van der Kouwe ,  Bruce Fischl ,  Lawrence Wald

发明人： Andre van der Kouwe ,  Bruce Fischl ,  Lawrence Wald

IPC分类号： A61B5/05 ,  G01R33/56 ,  A61B5/055 ,  G01R33/3415 ,  G01R33/54

CPC分类号： A61B5/055 ,  A61B5/0037 ,  G01R33/3415 ,  G01R33/543 ,  G01R33/56 ,  G01R33/5608

摘要： A system and method for performing an MRI or MRS scan that is optimized for a particular target structure. A prescan is conducted during a first session in which an image that is optimized for segmentation is acquired along with an alignment scout image or a 2D or 3D navigator signal. The segmentation process is employed to locate and define the target structure. During a second session the alignment scout image or navigator signal is reacquired and the information is used to determine the position transformation needed to align images from the two sessions. The position transformation information and the segmentation information are then employed to tailor a prescribed pulse sequence to examine the target structure.

摘要翻译： 用于执行针对特定目标结构优化的MRI或MRS扫描的系统和方法。 在第一会话期间进行预扫描，其中针对分割被优化的图像与对准侦察图像或2D或3D导航信号一起被获取。 采用分割过程来定位和定义目标结构。 在第二次会话期间，重新获取对准侦察图像或导航信号，并且使用该信息来确定对准来自两个会话的图像所需的位置变换。 然后使用位置变换信息和分割信息来定制规定的脉冲序列以检查目标结构。

公开(公告)号：US20080103383A1

公开(公告)日：2008-05-01

申请号：US11977153

申请日：2007-10-23

申请人： Andre van der Kouwe ,  Bruce Fischl ,  Lawrence Wald

发明人： Andre van der Kouwe ,  Bruce Fischl ,  Lawrence Wald

IPC分类号： A61B5/055

CPC分类号： A61B5/055 ,  A61B5/0037 ,  G01R33/3415 ,  G01R33/543 ,  G01R33/56 ,  G01R33/5608

摘要： A system and method for performing an MRI or MRS scan that is optimized for a particular target structure. A prescan is conducted during a first session in which an image that is optimized for segmentation is acquired along with an alignment scout image or a 2D or 3D navigator signal. The segmentation process is employed to locate and define the target structure. During a second session the alignment scout image or navigator signal is reacquired and the information is used to determine the position transformation needed to align images from the two sessions. The position transformation information and the segmentation information are then employed to tailor a prescribed pulse sequence to examine the target structure.

摘要翻译： 用于执行针对特定目标结构优化的MRI或MRS扫描的系统和方法。 在第一会话期间进行预扫描，其中针对分割被优化的图像与对准侦察图像或2D或3D导航信号一起被获取。 采用分割过程来定位和定义目标结构。 在第二次会话期间，重新获取对准侦察图像或导航信号，并且使用该信息来确定对准来自两个会话的图像所需的位置变换。 然后使用位置变换信息和分割信息来定制规定的脉冲序列以检查目标结构。

公开(公告)号：US20080116891A1

公开(公告)日：2008-05-22

申请号：US11562879

申请日：2006-11-22

申请人： Andre van der Kouwe ,  Bruce Fischl

发明人： Andre van der Kouwe ,  Bruce Fischl

IPC分类号： G01R33/48

CPC分类号： G01R33/561 ,  G01R33/5616

摘要： A system and method for medical imaging includes an improvement to the MP-RAGE pulse sequence that enables the readout bandwidth thereof to be matched to that of other pulse sequences used in the same examination without a significant loss in SNR. More specifically, the present invention includes using a multi-echo MP-RAGE pulse sequence in which multiple gradient-recalled NMR signals are acquired at the desired “matching” bandwidth and combining selected ones of the NMR signals to reconstruct an image. By selecting and combining NMR signals acquired at each phase encoding, the SNR of the resulting reconstructed image can be maintained.

摘要翻译： 用于医学成像的系统和方法包括对MP-RAGE脉冲序列的改进，其使得其读出带宽与在相同检查中使用的其它脉冲序列的读出带宽匹配，而没有SNR的显着损失。 更具体地，本发明包括使用多回波MP-RAGE脉冲序列，其中以期望的“匹配”带宽获取多个梯度回缩的NMR信号，并组合所选择的NMR信号以重建图像。 通过选择和组合在每个相位编码处获取的NMR信号，可以保持所得到的重建图像的SNR。

公开(公告)号：US07602179B2

公开(公告)日：2009-10-13

申请号：US11562879

申请日：2006-11-22

申请人： Andre van der Kouwe ,  Bruce Fischl

发明人： Andre van der Kouwe ,  Bruce Fischl

IPC分类号： G01V3/00

CPC分类号： G01R33/561 ,  G01R33/5616

摘要： A system and method for medical imaging includes an improvement to the MP-RAGE pulse sequence that enables the readout bandwidth thereof to be matched to that of other pulse sequences used in the same examination without a significant loss in SNR. More specifically, the present invention includes using a multi-echo MP-RAGE pulse sequence in which multiple gradient-recalled NMR signals are acquired at the desired “matching” bandwidth and combining selected ones of the NMR signals to reconstruct an image. By selecting and combining NMR signals acquired at each phase encoding, the SNR of the resulting reconstructed image can be maintained.

摘要翻译： 用于医学成像的系统和方法包括对MP-RAGE脉冲序列的改进，其使得其读出带宽与在相同检查中使用的其它脉冲序列的读出带宽匹配，而没有SNR的显着损失。 更具体地，本发明包括使用多回波MP-RAGE脉冲序列，其中以期望的“匹配”带宽获取多个梯度回缩的NMR信号，并组合所选择的NMR信号以重建图像。 通过选择和组合在每个相位编码处获取的NMR信号，可以保持所得到的重建图像的SNR。

公开(公告)号：US07432706B2

公开(公告)日：2008-10-07

申请号：US11735578

申请日：2007-04-16

申请人： Andre van der Kouwe

发明人： Andre van der Kouwe

IPC分类号： G01V3/00

CPC分类号： G01R33/4806 ,  G01R33/5616 ,  G01R33/56509 ,  G01R33/5676

摘要： An fMRI study is conducted using a 2D EPI pulse sequence. A separate blood flow navigator pulse sequence is interleaved with the fMRI data acquisition to monitor blood flow in arteries that feed the brain tissue. Information in the blood flow navigator data is used to reduce errors in the fMRI data due to tissue motion caused by pulsatile blood flow. In one embodiment the blood flow navigator information is used to gate the fMRI acquisition and in another embodiment the information is used to retrospectively correct acquired fMRI data.

摘要翻译： 使用2D EPI脉冲序列进行fMRI研究。 单独的血流导航仪脉冲序列与fMRI数据采集交错以监测供给脑组织的动脉中的血流。 血流导航器数据中的信息用于减少由脉动血流引起的组织运动引起的fMRI数据中的误差。 在一个实施例中，血流导航器信息用于门控fMRI采集，在另一个实施例中，该信息用于追溯地校正获取的fMRI数据。

公开(公告)号：US10045741B2

公开(公告)日：2018-08-14

申请号：US14449297

申请日：2014-08-01

申请人： Matthew Tisdall ,  Andre van der Kouwe

发明人： Matthew Tisdall ,  Andre van der Kouwe

IPC分类号： G01R33/565 ,  A61B5/00 ,  A61B5/055 ,  G01R33/561 ,  A61B5/08

摘要： Systems and methods for estimating frequency drifts in magnetic resonance signals acquired with a magnetic resonance imaging (“MRI”) system are provided. In one example, the frequency drifts are estimated from phase-correction data that are obtained during an echo-planar imaging (“EPI”), or other multiecho imaging, scan. The systems and methods of the present invention provide for efficiently and accurately computing frequency drift values that can be used for real-time, prospective frequency drift correction.

公开(公告)号：US20100261993A1

公开(公告)日：2010-10-14

申请号：US12423303

申请日：2009-04-14

申请人： Andre van der Kouwe ,  Thomas Banner

发明人： Andre van der Kouwe ,  Thomas Banner

IPC分类号： A61B5/055 ,  G06K9/00

CPC分类号： G01R33/482 ,  A61B5/055 ,  G01R33/481 ,  G01R33/4816 ,  G01R33/4824 ,  G01R33/5613

摘要： A system and method for producing MR images in which bone and soft tissue are identified. The method includes applying a pulse sequence that includes a first stage configured to acquire a radially-encoded FID and radially-encoded echoes performed after a non-selective RF excitation pulse and before a second stage, which is configured to acquire additional echoes. The radially-encoded MR data acquired during the first stage is substantially representative of bone, while the MR data acquired during the second stage is substantially representative of soft tissues. MR images in which bone and soft tissue are identified are reconstructed from these MR data sets.

摘要翻译： 用于产生其中识别骨和软组织的MR图像的系统和方法。 该方法包括应用脉冲序列，该脉冲序列包括被配置为获取径向编码的FID的第一级和在非选择性RF激励脉冲之后以及被配置为获取附加回波的第二级之前执行的径向编码回波。 在第一阶段期间获得的径向编码的MR数据基本上代表骨骼，而在第二阶段期间获取的MR数据基本上代表软组织。 从这些MR数据集重建其中识别骨和软组织的MR图像。

公开(公告)号：US09213074B2

公开(公告)日：2015-12-15

申请号：US12423303

申请日：2009-04-14

申请人： Andre van der Kouwe ,  Thomas Benner

发明人： Andre van der Kouwe ,  Thomas Benner

IPC分类号： A61B5/05 ,  G01R33/48 ,  A61B5/055 ,  G01R33/561

CPC分类号： G01R33/482 ,  A61B5/055 ,  G01R33/481 ,  G01R33/4816 ,  G01R33/4824 ,  G01R33/5613

摘要： A system and method for producing MR images in which bone and soft tissue are identified. The method includes applying a pulse sequence that includes a first stage configured to acquire a radially-encoded FID and radially-encoded echoes performed after a non-selective RF excitation pulse and before a second stage, which is configured to acquire additional echoes. The radially-encoded MR data acquired during the first stage is substantially representative of bone, while the MR data acquired during the second stage is substantially representative of soft tissues. MR images in which bone and soft tissue are identified are reconstructed from these MR data sets.

摘要翻译： 用于产生其中识别骨和软组织的MR图像的系统和方法。 该方法包括应用脉冲序列，该脉冲序列包括被配置为获取径向编码的FID的第一级和在非选择性RF激励脉冲之后以及被配置为获取附加回波的第二级之前执行的径向编码回波。 在第一阶段期间获得的径向编码的MR数据基本上代表骨骼，而在第二阶段期间获取的MR数据基本上代表软组织。 从这些MR数据集重建其中识别骨和软组织的MR图像。

公开(公告)号：US20150035530A1

公开(公告)日：2015-02-05

申请号：US14449297

申请日：2014-08-01

申请人： Matthew Tisdall ,  Andre van der Kouwe

发明人： Matthew Tisdall ,  Andre van der Kouwe

IPC分类号： G01R33/567 ,  A61B5/00 ,  A61B5/0402 ,  G01R33/561 ,  A61B5/08

CPC分类号： A61B5/7285 ,  A61B5/055 ,  A61B5/0816 ,  A61B5/7203 ,  G01R33/5616 ,  G01R33/565 ,  G01R33/56509 ,  G01R33/56518 ,  G01R33/56563

摘要： Systems and methods for estimating frequency drifts in magnetic resonance signals acquired with a magnetic resonance imaging (“MRI”) system are provided. In one example, the frequency drifts are estimated from phase-correction data that are obtained during an echo-planar imaging (“EPI”), or other multiecho imaging, scan. The systems and methods of the present invention provide for efficiently and accurately computing frequency drift values that can be used for real-time, prospective frequency drift correction.

摘要翻译： 提供用于估计用磁共振成像（“MRI”）系统获取的磁共振信号中的频率漂移的系统和方法。 在一个示例中，通过在回波平面成像（“EPI”）或其他多重成像扫描期间获得的相位校正数据来估计频率漂移。 本发明的系统和方法提供了有效和准确地计算可用于实时，预期频率漂移校正的频率漂移值。

公开(公告)号：US20070247150A1

公开(公告)日：2007-10-25

申请号：US11735578

申请日：2007-04-16

申请人： Andre van der Kouwe

发明人： Andre van der Kouwe

IPC分类号： G01V3/00

CPC分类号： G01R33/4806 ,  G01R33/5616 ,  G01R33/56509 ,  G01R33/5676

摘要： An fMRI study is conducted using a 2D EPI pulse sequence. A separate blood flow navigator pulse sequence is interleaved with the fMRI data acquisition to monitor blood flow in arteries that feed the brain tissue. Information in the blood flow navigator data is used to reduce errors in the fMRI data due to tissue motion caused by pulsatile blood flow. In one embodiment the blood flow navigator information is used to gate the fMRI acquisition and in another embodiment the information is used to retrospectively correct acquired fMRI data.

摘要翻译： 使用2D EPI脉冲序列进行fMRI研究。 单独的血流导航仪脉冲序列与fMRI数据采集交错以监测供给脑组织的动脉中的血流。 血流导航器数据中的信息用于减少由脉动血流引起的组织运动引起的fMRI数据中的误差。 在一个实施例中，血流导航器信息用于门控fMRI采集，在另一个实施例中，该信息用于追溯地校正获取的fMRI数据。