公开(公告)号：US10858389B2

公开(公告)日：2020-12-08

申请号：US15561009

申请日：2016-03-25

Applicant: Amgen Inc.

Inventor： Sheng Cui ,  Krishnakumar Ranganathan ,  Richard Crockett ,  Ying Chen ,  Aleksander Swietlow ,  Kevin Crossley ,  Yun Shi ,  Karel Decroos ,  Etienne Moniotte

IPC: C07K1/02 ,  C07K7/06 ,  C07K1/18 ,  C07K5/083 ,  C07K5/11

Abstract: The instant disclosure is directed to solution phase fragment coupling methods for preparing etelcalcetide and its pharmaceutically acceptable salts.

公开(公告)号：US20180079777A1

公开(公告)日：2018-03-22

申请号：US15561009

申请日：2016-03-25

Applicant: Amgen Inc.

Inventor： Sheng Cui ,  Krishnakumar Ranganathan ,  Richard Crockett ,  Ying Chen ,  Aleksander Swietlow ,  Kevin Crossley ,  Yun Shi ,  Karel Decroos ,  Etienne Moniotte

IPC: C07K1/02 ,  C07K7/06 ,  C07K1/18

CPC classification number: C07K1/026 ,  C07K1/18 ,  C07K5/081 ,  C07K5/1019 ,  C07K7/06

Abstract: The instant disclosure is directed to solution phase fragment coupling methods for preparing etelcalcetide and its pharmaceutically acceptable salts.