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公开(公告)号:US20230082811A1
公开(公告)日:2023-03-16
申请号:US17930810
申请日:2022-09-09
Applicant: Amgen Inc.
Inventor: Kristine Marie DARIS , Huong Thi Ngoc LE , Eric GISLASON , Trent Phillip MUNRO
Abstract: Methods producing a recombinant protein of interest in a mammalian cell culture in media lacking IGF-1 are provided. Methods for producing mammalian cells capable of growing in media lacking IGF-1 are also provided.