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公开(公告)号：US20230172842A1
公开(公告)日：2023-06-08
申请号：US17812946
申请日：2022-07-15
申请人： Allergan, Inc.
发明人： Jane-Guo Shiah , Chetan Pujara
IPC分类号： A61K9/00 , A61F9/00 , A61K31/498 , A61K47/32
CPC分类号： A61K9/0051 , A61F9/0017 , A61K31/498 , A61K47/32 , A61F2210/0004
摘要： Biocompatible intraocular implants may include a brimonidine free base and a biodegradable polymer associated with the brimonidine free base to facilitate the release of the brimonidine free base into an eye with the polymer matrix lasts a period of time of not more than twice the drug release duration, but more than the drug release duration.
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公开(公告)号：US20220218599A1
公开(公告)日：2022-07-14
申请号：US17455375
申请日：2021-11-17
申请人： Allergan, Inc.
发明人： Yumna Shabaik , Jim Jiao , Chetan Pujara
IPC分类号： A61K9/00 , A61K47/10 , A61K47/26 , A61K47/44 , A61K31/573 , A61K47/14 , A61K9/107 , A61K31/498 , A61K31/542 , A61K31/568 , A61K31/138
摘要： Provided herein are topical ophthalmic preparations which comprise a non-aqueous, self-emulsifying system which can spontaneously give rise to either nanosized emulsions upon contact with an aqueous phase. Also provided herein are methods for the preparation of the same and their use in formulating and delivering poorly water soluble drugs.
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公开(公告)号：US20190209467A1
公开(公告)日：2019-07-11
申请号：US16354692
申请日：2019-03-15
申请人： Allergan, Inc.
发明人： Jane-Guo Shiah , Chetan Pujara
IPC分类号： A61K9/00 , A61K31/498 , A61F9/00 , A61K47/32
CPC分类号： A61K9/0051 , A61F9/0017 , A61F2210/0004 , A61K31/498 , A61K47/32 , Y10S514/912 , Y10S514/913 , Y10S514/953 , Y10S514/954 , Y10S514/956
摘要： Biocompatible intraocular implants may include a brimonidine free base and a biodegradable polymer associated with the brimonidine free base to facilitate the release of the brimonidine free base into an eye with the polymer matrix lasts a period of time of not more than twice the drug release duration, but more than the drug release duration.
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公开(公告)号：US20180036233A1
公开(公告)日：2018-02-08
申请号：US15554983
申请日：2016-03-02
申请人： Allergan, Inc.
发明人： Yumna Shabaik , Jim Jiao , Chetan Pujara
CPC分类号： A61K9/0048 , A61K9/107 , A61K9/1075 , A61K31/138 , A61K31/498 , A61K31/542 , A61K31/568 , A61K31/573 , A61K47/10 , A61K47/14 , A61K47/26 , A61K47/44
摘要： Provided herein are topical ophthalmic preparations which comprise a non-aqueous, self-emulsifying system which can spontaneously give rise to either nanosized emulsions upon contact with an aqueous phase. Also provided herein are methods for the preparation of the same and their use in formulating and delivering poorly water soluble drugs.
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公开(公告)号：US11045515B2
公开(公告)日：2021-06-29
申请号：US15791158
申请日：2017-10-23
申请人： ALLERGAN, INC.
发明人： Anuradha V. Gore , Robert S. Jordan , Kevin Krock , Chetan Pujara
摘要： The present invention provides ophthalmic compositions, e.g. artificial tears, suitable for treating dry eye syndrome in a human or other mammal suffering there from, e.g. a dog or cat, which comprise a mixture of castor oil with another oil, e.g. a food oil, e.g. olive oil, sesame oil, corn oil etc.
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公开(公告)号：US20210113458A1
公开(公告)日：2021-04-22
申请号：US16984971
申请日：2020-08-04
申请人： Allergan, Inc.
发明人： Jane-Guo Shiah , Chetan Pujara
IPC分类号： A61K9/00 , A61F9/00 , A61K31/498 , A61K47/32
摘要： Biocompatible intraocular implants may include a brimonidine free base and a biodegradable polymer associated with the brimonidine free base to facilitate the release of the brimonidine free base into an eye with the polymer matrix lasts a period of time of not more than twice the drug release duration, but more than the drug release duration.
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公开(公告)号：US10231926B2
公开(公告)日：2019-03-19
申请号：US15350577
申请日：2016-11-14
申请人： Allergan, Inc.
发明人： Jane-Guo Shiah , Chetan Pujara
IPC分类号： A61K31/498 , A61K47/32 , A61K9/00 , A61F9/00
摘要： Biocompatible intraocular implants may include a brimonidine free base and a biodegradable polymer associated with the brimonidine free base to facilitate the release of the brimonidine free base into an eye with the polymer matrix lasts a period of time of not more than twice the drug release duration, but more than the drug release duration.
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公开(公告)号：US20240307299A1
公开(公告)日：2024-09-19
申请号：US18516480
申请日：2023-11-21
申请人： Allergan, Inc.
发明人： Yumna Shabaik , Jim Jiao , Chetan Pujara
IPC分类号： A61K9/00 , A61K9/107 , A61K31/138 , A61K31/498 , A61K31/542 , A61K31/568 , A61K31/573 , A61K47/10 , A61K47/14 , A61K47/26 , A61K47/44
CPC分类号： A61K9/0048 , A61K9/107 , A61K9/1075 , A61K31/138 , A61K31/498 , A61K31/542 , A61K31/568 , A61K31/573 , A61K47/10 , A61K47/14 , A61K47/26 , A61K47/44
摘要： Provided herein are topical ophthalmic preparations which comprise a non-aqueous, self-emulsifying system which can spontaneously give rise to either nanosized emulsions upon contact with an aqueous phase. Also provided herein are methods for the preparation of the same and their use in formulating and delivering poorly water soluble drugs.
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公开(公告)号：US20240108677A1
公开(公告)日：2024-04-04
申请号：US18364692
申请日：2023-08-03
申请人： Allergan, Inc.
发明人： Anuradha V. Gore , Robert S. Jordan , Kevin Krock , Chetan Pujara
CPC分类号： A61K36/55 , A61K9/0048 , A61K9/107 , A61K36/47 , A61K47/44
摘要： The present invention provides ophthalmic compositions, e.g. artificial tears, suitable for treating dry eye syndrome in a human or other mammal suffering there from, e.g. a dog or cat, which comprise a mixture of castor oil with another oil, e.g. a food oil, e. g. olive oil, sesame oil, corn oil etc.
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公开(公告)号：US09821020B2
公开(公告)日：2017-11-21
申请号：US14166589
申请日：2014-01-28
申请人： ALLERGAN, INC.
发明人： Anuradha V. Gore , Robert S. Jordan , Kevin Krock , Chetan Pujara
CPC分类号： A61K36/55 , A61K9/0048 , A61K9/107 , A61K36/47 , A61K47/44
摘要： The present invention provides ophthalmic compositions, e.g. artificial tears, suitable for treating dry eye syndrome in a human or other mammal suffering there from, e.g. a dog or cat, which comprise a mixture of castor oil with another oil, e.g. a food oil, e.g. olive oil, sesame oil, corn oil etc.
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