CALIBRATION OF IMAGING SYSTEM WITH COMBINED OPTICAL COHERENCE TOMOGRAPHY AND VISUALIZATION MODULE

    公开(公告)号:US20240027180A1

    公开(公告)日:2024-01-25

    申请号:US18354096

    申请日:2023-07-18

    Applicant: Alcon Inc.

    CPC classification number: G01B9/02072 A61B3/102 A61B90/20 G01B9/02091

    Abstract: An imaging system includes a housing assembly having a head unit configured to be at least partially directed towards a target site. An optical coherence tomography (OCT) module and a visualization module are located in the housing assembly and configured to respectively obtain OCT data and visualization data of the target site. The system includes a controller configured to generate a scanning pattern for a region of calibration selected in a calibration target. OCT data of the region of calibration is synchronously acquired. The controller is configured to obtain a projected two-dimensional OCT image of the region of calibration based on the OCT data, as an inverse mean-intensity projection. The controller is configured to register the projected two-dimensional OCT image to a corresponding view extracted from the visualization data, via a cascaded image registration process having a coarse registration stage and a fine registration stage.

    IMAGING MARKERS FOR VERIFYING BIOMETRY

    公开(公告)号:US20220095909A1

    公开(公告)日:2022-03-31

    申请号:US17477682

    申请日:2021-09-17

    Applicant: Alcon Inc.

    Abstract: The systems and methods described herein provide improved techniques for displaying imaging markers for verifying biometry. A method includes receiving an indication to initiate a first optical coherence tomography (OCT) scanning of an eye; initiating, based on the received indication, the first OCT scanning of the eye; generating, based on the first OCT scanning, a first OCT image of the eye; detecting, based on the first OCT image, a retinal pigment epithelium (RPE) and a fovea in the eye; based on the detecting, causing a first enhanced OCT image to be displayed to a user, the first enhanced OCT image displaying: a first virtual marker segmenting at least a portion of the detected RPE, and a second virtual marker, where the second virtual marker visually identifies a location of the detected fovea, and where the second virtual marker is a radial line through the location of the detected fovea.

    POLARIZATION SENSITIVE OPTICAL COHERENCE TOMOGRAPHY FOR VISUALIZATION OF VITREOUS OPACITIES

    公开(公告)号:US20250090015A1

    公开(公告)日:2025-03-20

    申请号:US18828214

    申请日:2024-09-09

    Applicant: Alcon Inc.

    Abstract: A system of visualizing a target site in an eye, using a polarization sensitive optical coherence tomography (PS-OCT) device, includes a controller having at least one processor and at least one non-transitory, tangible memory on which instructions are recorded. The target site is one or more vitreous opacities in the vitreous humor of the eye. The controller is configured to receive PS-OCT data and determine at least one parameter corresponding to birefringence properties of collagen fibrils in the vitreous humor based on the PS-OCT data. The at least one parameter includes respective spacing of the collagen fibrils. The controller is configured to determine a respective location of the one or more vitreous opacities when the at least one parameter is outside a predefined range and generate a control signal adapted for guiding a treatment beam at the respective location of the one or more vitreous opacities.

    IMAGING MARKERS FOR VERIFYING BIOMETRY

    公开(公告)号:US20250143563A1

    公开(公告)日:2025-05-08

    申请号:US19018234

    申请日:2025-01-13

    Applicant: Alcon Inc.

    Abstract: The systems and methods described herein provide improved techniques for displaying imaging markers for verifying biometry. A method includes receiving an indication to initiate a first optical coherence tomography (OCT) scanning of an eye; initiating, based on the received indication, the first OCT scanning of the eye; generating, based on the first OCT scanning, a first OCT image of the eye; detecting, based on the first OCT image, a retinal pigment epithelium (RPE) and a fovea in the eye; based on the detecting, causing a first enhanced OCT image to be displayed to a user, the first enhanced OCT image displaying: a first virtual marker segmenting at least a portion of the detected RPE, and a second virtual marker, where the second virtual marker visually identifies a location of the detected fovea, and where the second virtual marker is a radial line through the location of the detected fovea.

    CORNEAL EPITHELIUM SEGMENTATION IN OPTICAL COHERENCE TOMOGRAPHY IMAGES

    公开(公告)号:US20220148187A1

    公开(公告)日:2022-05-12

    申请号:US17453559

    申请日:2021-11-04

    Applicant: Alcon Inc.

    Abstract: The systems and methods described herein provide improved techniques for segmenting corneal epithelium layer. A method includes receiving an optical coherence tomography (OCT) image of an eye; generating, based on the OCT image, a binarized image of the eye; generating, based on the binarized image of the eye and the OCT image, a binary mask of a cornea of the eye; segmenting, based on the binary mask of the cornea of the eye, an anterior cornea of the eye on the OCT image; generating, based on the OCT image and the segmented anterior cornea of the eye, a binary mask for an epithelium layer of the eye; segmenting, based on the binary mask for the epithelium layer of the eye, a Bowman's layer in the cornea of the eye on the OCT image; and causing the segmented anterior cornea and the segmented Bowman's layer data to be used for generation of an epithelium map.

    Imaging markers for verifying biometry

    公开(公告)号:US12226155B2

    公开(公告)日:2025-02-18

    申请号:US17477682

    申请日:2021-09-17

    Applicant: Alcon Inc.

    Abstract: The systems and methods described herein provide improved techniques for displaying imaging markers for verifying biometry. A method includes receiving an indication to initiate a first optical coherence tomography (OCT) scanning of an eye; initiating, based on the received indication, the first OCT scanning of the eye; generating, based on the first OCT scanning, a first OCT image of the eye; detecting, based on the first OCT image, a retinal pigment epithelium (RPE) and a fovea in the eye; based on the detecting, causing a first enhanced OCT image to be displayed to a user, the first enhanced OCT image displaying: a first virtual marker segmenting at least a portion of the detected RPE, and a second virtual marker, where the second virtual marker visually identifies a location of the detected fovea, and where the second virtual marker is a radial line through the location of the detected fovea.

    Corneal epithelium segmentation in optical coherence tomography images

    公开(公告)号:US12211211B2

    公开(公告)日:2025-01-28

    申请号:US17453559

    申请日:2021-11-04

    Applicant: Alcon Inc.

    Abstract: The techniques described herein provide improved techniques for segmenting corneal epithelium layer. A method includes receiving an optical coherence tomography (OCT) image of an eye; generating, based on the OCT image, a binarized image of the eye; generating, based on the binarized image of the eye and the OCT image, a binary mask of a cornea of the eye; segmenting, based on the binary mask of the cornea of the eye, an anterior cornea of the eye on the OCT image; generating, based on the OCT image and the segmented anterior cornea, a binary mask for an epithelium layer of the eye; segmenting, based on the binary mask for the epithelium layer of the eye, a Bowman's layer in the cornea of the eye on the OCT image; and causing the segmented anterior cornea and the segmented Bowman's layer data to be used for generation of an epithelium map.

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