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公开(公告)号：US20240272051A1
公开(公告)日：2024-08-15
申请号：US18632030
申请日：2024-04-10
Applicant: Agilent Technologies, Inc.
Inventor： Victor Lim , Carol T. Schembri , Adrienne Mccampbell , Nazumi Alice Yama-Dang
CPC classification number: G01N1/44 , G01N1/30 , G01N1/31 , G01N1/312 , G01N1/36 , G01N1/40 , G01N2001/366 , G01N2001/4038
Abstract: Paraffin-embedded tissue, which may be disposed on a solid substrate, is prepared by a dry technique that removes paraffin from tissue without adding any liquid to the tissue, thereby rendering the tissue substantially free of paraffin. The dry technique may entail applying heat energy to the tissue effective to melt the paraffin and thereby render it flowable, and applying an electric field. The electric field is effective to impart electrical charge to the paraffin and to move the paraffin out from the tissue due to electrical charge repulsion or attraction, which may be assisted by moving an electrode utilized to generate the electric field relative to the paraffin. The electric field, or both the electric field and the heat energy, may be applied until the tissue is substantially free of paraffin.
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公开(公告)号：US11982606B2
公开(公告)日：2024-05-14
申请号：US16803503
申请日：2020-02-27
Applicant: Agilent Technologies, Inc.
Inventor： Victor Lim , Carol T. Schembri , Adrienne Mccampbell , Nazumi Alice Yama-Dang
CPC classification number: G01N1/44 , G01N1/30 , G01N1/31 , G01N1/312 , G01N1/36 , G01N1/40 , G01N2001/366 , G01N2001/4038
Abstract: Paraffin-embedded tissue, which may be disposed on a solid substrate, is prepared by a dry technique that removes paraffin from tissue without adding any liquid to the tissue, thereby rendering the tissue substantially free of paraffin. The dry technique may entail applying heat energy to the tissue effective to melt the paraffin and thereby render it flowable, and applying an electric field. The electric field is effective to impart electrical charge to the paraffin and to move the paraffin out from the tissue due to electrical charge repulsion or attraction, which may be assisted by moving an electrode utilized to generate the electric field relative to the paraffin. The electric field, or both the electric field and the heat energy, may be applied until the tissue is substantially free of paraffin.
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公开(公告)号：US20230236211A1
公开(公告)日：2023-07-27
申请号：US18001581
申请日：2021-06-11
Applicant: Agilent Technologies, Inc.
Inventor： Rolfe Anderson , Adrienne Mccampbell , Victor Lim , Carol T. Schembri , Michal Johannsen , Fleming Lassen Nielsen
CPC classification number: G01N35/00029 , G01N1/312 , G01N1/30 , G01N2035/00079 , G01N2035/00138 , G01N2035/00089 , G01N2035/00346 , G01N2001/305 , G01N2001/302
Abstract: Systems and methods for coverslipping a sample on a slide employ a coverslip tape. The systems and methods can reduce or eliminate the use of xylene and other toxic solvents for coverslipping.
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公开(公告)号：US20180120207A1
公开(公告)日：2018-05-03
申请号：US15797232
申请日：2017-10-30
Applicant: Agilent Technologies, Inc.
Inventor： Victor Lim , Carol T. Schembri , Adrienne Mccampbell , Nazumi Alice Yama-Dang
CPC classification number: G01N1/44 , G01N1/30 , G01N1/312 , G01N1/36 , G01N1/40 , G01N2001/366 , G01N2001/4038
Abstract: Paraffin-embedded tissue, which may be disposed on a solid substrate, is prepared by a dry technique that removes paraffin from tissue without adding any liquid to the tissue, thereby rendering the tissue substantially free of paraffin. The dry technique may entail applying heat energy to the tissue effective to melt the paraffin and thereby render it flowable, and applying an electric field. The electric field is effective to impart electrical charge to the paraffin and to move the paraffin out from the tissue due to electrical charge repulsion or attraction, which may be assisted by moving an electrode utilized to generate the electric field relative to the paraffin. The electric field, or both the electric field and the heat energy, may be applied until the tissue is substantially free of paraffin.
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