公开(公告)号：US20220064589A1

公开(公告)日：2022-03-03

申请号：US17527002

申请日：2021-11-15

申请人： ATOGEN CO., LTD.

发明人： Bo Ram BECK ,  Ji Hii KANG ,  Gun Seok PARK ,  Sung Hoon IM ,  Do Yeun JEONG ,  Yong Hyun LEE

IPC分类号： C12N1/20 ,  A61P15/02 ,  A61K35/74 ,  A61K35/747

摘要： A novel Lactobacillus plantarum strain ATG-K2, ATG-K6 or ATG-K8 and a composition for the prevention or treatment of vaginitis containing the same are proposed. The Lactobacillus plantarum strain ATG-K2, ATG-K6 or ATG-K8 has excellent antimicrobial effects against various pathogenic strains as well as Candida albicans and Gardnerella vaginalis, which are vaginitis pathogens, and thus can be easily used as a composition for the treatment of bacterial vaginosis, vaginal candidiasis, etc., or as a functional health food for the prevention or amelioration of these diseases.

公开(公告)号：US20240207333A1

公开(公告)日：2024-06-27

申请号：US18288640

申请日：2022-04-14

申请人： Ji Hee KANG ,  ATOGEN CO., LTD ,  M. S. BIOTECH CO., LTD

发明人： Ji Hee KANG ,  Yeon Hwa PARK ,  Dong Kwan JU ,  Yo Han JU ,  Ye Won KANG ,  Gun Seok PARK ,  Seung Hyun KO

IPC分类号： A61K35/747 ,  A61P1/14 ,  A61P37/04 ,  C12N1/20 ,  C12R1/225

CPC分类号： A61K35/747 ,  A61P1/14 ,  A61P37/04 ,  C12N1/205 ,  C12R2001/225

摘要： The present invention relates to a novel lactobacillus fermentum ATG-V5 strain or a composition for enhancing immunity, comprising same. The Lactobacillus fermentum ATG-V5 strain of the present invention has no cytotoxicity, and has the effect of enhancing immunity, such as increasing the amounts of nitric oxide (NO), interleukin 6 (IL-6) and tumor necrosis factor (TNF) secretion and phagocytosis of macrophages, reducing the amount of interleukin 1β (IL-1β) secretion of macrophages, increasing the cell viability of splenocytes, and increasing the amount of antibodies and cytokines secretion in the blood, and thus the strain can be effectively used as a material for a composition and a health functional food for enhancing immunity, and the composition and health functional food can be effectively used in enhancing individual immune activity. In addition, a health functional food comprising the food composition is also effective in enhancing individual immune activity.

公开(公告)号：US20220211779A1

公开(公告)日：2022-07-07

申请号：US17605391

申请日：2019-12-13

申请人： ATOGEN CO., LTD.

发明人： Do Yeun JEONG ,  Bo Ram BECK ,  Ji Hee KANG ,  Yong Hyun LEE ,  Gun Seok PARK ,  Sung Hoon IM ,  Won Ho SONG

IPC分类号： A61K35/747 ,  A61P21/00

摘要： The present invention relates to a composition for the prevention or treatment of sarcopenia, the composition including a Lactobacillus reuteri ATG-F4 strain. More specifically, the strain exhibits an effect of improving muscle rehabilitation and motor ability by increasing the muscle mass in skeletal muscles, thereby being suitably used as an ingredient for compositions for the prevention or treatment of sarcopenia or muscular atrophy.

公开(公告)号：US20220143112A1

公开(公告)日：2022-05-12

申请号：US17600650

申请日：2019-06-10

申请人： ATOGEN CO., LTD

发明人： Yong Hyun LEE ,  Bo Ram BECK ,  Ji Hee KANG ,  Do Yeun JEONG ,  Gun Seok PARK ,  Sung Hoon IM ,  Won Ho SONG

IPC分类号： A61K35/745 ,  A23L33/135 ,  A61P17/10 ,  A61P17/18 ,  A61P29/00 ,  C12N1/20

摘要： The present invention relates to a novel Bifidobacterium longum ATG-F5 strain. The F5 strain is a functional beneficial bacterium which is safe from antibiotic resistance, improves skin health through antibacterial activity against the skin pathogen Cutibacterium acnes, an antioxidant effect on radicals, skin barrier improvement, and anti-inflammatory effects, and enhances skin beauty through a skin whitening function, a wrinkle improvement function, and a dry skin alleviation function. The strain may be used in a cosmetic composition or health functional food.

公开(公告)号：US20210324326A1

公开(公告)日：2021-10-21

申请号：US17051007

申请日：2019-06-10

申请人： ATOGEN CO., LTD

发明人： Bo Ram BECK ,  Ji Hee KANG ,  Gun Seok PARK ,  Sung Hoon IM ,  Do Yeun JEONG ,  Yong Hyun LEE

IPC分类号： C12N1/20 ,  A61K35/74 ,  A61P15/02

摘要： A novel Lactobacillus plantarum strain ATG-K2, ATG-K6 or ATG-K8 and a composition for the prevention or treatment of vaginitis containing the same are proposed. The Lactobacillus plantarum strain ATG-K2, ATG-K6 or ATG-K8 has excellent antimicrobial effects against various pathogenic strains as well as Candida albicans and Gardnerella vaginalis, which are vaginitis pathogens, and thus can be easily used as a composition for the treatment of bacterial vaginosis, vaginal candidiasis, etc., or as a functional health food for the prevention or amelioration of these diseases.

公开(公告)号：US20210228658A1

公开(公告)日：2021-07-29

申请号：US17050971

申请日：2019-06-10

申请人： ATOGEN CO., LTD

发明人： Bo Ram BECK ,  Ji Hee KANG ,  Gun Seok PARK ,  Sung Hoon IM ,  Do Yeun JEONG ,  Yong Hyun LEE

IPC分类号： A61K35/747 ,  A23L33/135

摘要： A Lactobacillus reuteri ATG-F4 strain (Accession number KCTC13717BP) is proposed. The strain has the function of enhancing dopamine secretion, and thus can be used as a pharmaceutical composition or a functional health food for the prevention or amelioration of mental illnesses, such as memory disorder, depressive disorder, generalized anxiety disorder, bipolar disorder, and the like, as well as Parkinson's disease, or can be used as a very effective composition for the improvement of memory or cognitive function. Moreover, the strain exhibits anti-inflammatory efficacy of upregulating the expression of IL-10 (interleukin-10) and inhibiting the generation of nitric oxide (NO) and is not resistant to antibiotics, and can thus be readily applied to a variety of foods having health improvement effects.