-
公开(公告)号：US11702640B2
公开(公告)日：2023-07-18
申请号：US16966548
申请日：2018-02-08
发明人： Hao Hong , James Gage , Jiangping Lu , Xuecheng Jiao , Na Zhang , Rui Li , Kejian Zhang , Yu Zhang
CPC分类号： C12N9/0073 , C12Y114/13022
摘要： The present application relates to the technical field of genetic engineering, and provides a monooxygenase mutant, a preparation method and application thereof. The monooxygenase mutant has any one of the amino acid sequences shown in (I) and (II): (I) an amino acid sequence having at least 80% identity with the amino acid sequence shown in SEQ ID NO. 1; and (II) an amino acid sequence obtained by modifying, substituting, deleting, or adding one or several amino acids to the amino acids at 23 to 508 positions of the amino acid sequence shown in SEQ ID NO. 1, the substituting referring to a substitution of 1 to 34 amino acids, wherein the mutant has the activity of monooxygenase.
-
公开(公告)号：US12098394B2
公开(公告)日：2024-09-24
申请号：US17290749
申请日：2018-11-05
发明人： Hao Hong , Gage James , Jiangping Lu , Xuecheng Jiao , Na Zhang , Kejian Zhang , Rui Li , Yu Zhang , Yiming Yang
CPC分类号： C12N9/0006 , C12P11/00
摘要： An amino acid sequence of the monooxygenase mutant is obtained by mutation of an amino acid sequence shown in SEQ ID NO: 1, and the mutation at least includes one of the following mutation sites: 45-th site, 95-th site, 106-th site, 108-th site, 114-th site, 186-th site, 190-th site, 191-th site, 249-th site, 257-th site, 393-th site, 436-th site, 499-th site, 500-th site, 501-th site, 503-th site, 504-th site, 559-th site, and 560-th site.
-
搜索结果
2 条记录 (耗时 0.013 秒)
