公开(公告)号：US20170209836A1

公开(公告)日：2017-07-27

申请号：US15514863

申请日：2015-09-29

申请人： ASAHI KASEI MEDICAL CO., LTD.

发明人： Yosuke HATA ,  Chiharu KAWANO ,  Ryoko HORI

IPC分类号： B01D69/08 ,  B01D71/58 ,  B01D71/12 ,  B01D71/68

CPC分类号： B01D69/08 ,  A61M1/16 ,  B01D63/02 ,  B01D65/022 ,  B01D67/0088 ,  B01D69/02 ,  B01D71/12 ,  B01D71/16 ,  B01D71/58 ,  B01D71/68 ,  B01D2313/20 ,  B01D2323/46 ,  B01D2325/44

摘要： The present invention provides a hollow-fiber membrane blood purification device obtained by filling a container with a hollow-fiber membrane, in which the hollow-fiber membrane contains a hydrophobic polymer, a hydrophilic polymer and a lipid-soluble substance; the amount of the lipid-soluble substance on the inner surface of the hollow-fiber membrane is 10 mg/m2 or more and 300 mg/m2 or less; and the oxygen transmission rate of the container is 1.8×10−10 cm3·cm/(cm2·s·cmHg) or less.

公开(公告)号：US20160354728A1

公开(公告)日：2016-12-08

申请号：US15104072

申请日：2014-12-16

申请人： ASAHI KASEI MEDICAL CO., LTD.

发明人： Ryoko HORI ,  Yosuke HATA ,  Junya KAWAKAMI

IPC分类号： B01D69/14 ,  C08L33/12 ,  A61M1/16 ,  C08L81/06 ,  B01D63/02 ,  B01D69/08

CPC分类号： B01D69/144 ,  A61M1/16 ,  A61M1/1621 ,  B01D63/02 ,  B01D63/021 ,  B01D63/023 ,  B01D65/10 ,  B01D67/0088 ,  B01D69/08 ,  B01D71/68 ,  B01D2323/08 ,  B01D2323/12 ,  B01D2323/22 ,  B01D2325/06 ,  C08L33/12 ,  C08L81/06 ,  C08L2201/08 ,  C08L2203/02 ,  C08L2203/12 ,  C08L2205/025

摘要： Disclosed is a hollow-fiber membrane blood purification device having an improved antioxidant performance, good water permeation performance and blood compatibility performance, and economic rationality. The present invention provides a hollow-fiber membrane blood purification device including hollow-fiber membranes filled in a vessel, in which the hollow-fiber membranes contain a hydrophobic polymer, a hydrophilic polymer and a fat-soluble vitamin, when a hollow-fiber membrane bundle is divided into five sections in a lengthwise direction and divided sections positioned in endmost portions are defined as body end portions, an amount of the fat-soluble vitamin present in at least one of the body end portions is the largest among amounts of the fat-soluble vitamin present respectively in all the divided sections, and an amount of the fat-soluble vitamin per m2 of a hollow-fiber membrane inner surface of the at least one body end portion is 20 mg/m2 or more and 300 mg/m2 or less.

摘要翻译： 公开了具有改进的抗氧化性能，良好的水渗透性能和血液相容性能以及经济合理性的中空纤维膜血液净化装置。 本发明提供了一种中空纤维膜血液净化装置，其包括填充在容器中的中空纤维膜，其中中空纤维膜含有疏水性聚合物，亲水性聚合物和脂溶性维生素，当中空纤维膜 束在长度方向上分为五个部分，并且位于最末端的分割部分被定义为主体端部，存在于至少一个身体端部中的脂溶性维生素的量在脂肪的量中最大 所有分割部分分别存在可溶性维生素，至少一个身体端部的中空纤维膜内表面的每1m2的脂溶性维生素的量为20mg / m 2以上且300mg / m 2 或更少。