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公开(公告)号：US20240352428A1
公开(公告)日：2024-10-24
申请号：US18294138
申请日：2022-08-02
CPC分类号： C12N7/00 , C12N9/22 , C12N9/88 , C12N15/11 , C12N15/90 , C12Y402/02003 , C12Y402/02011 , C12N2310/20 , C12N2795/00022 , C12N2795/00033
摘要： Provided herein are bacteriophages engineered to express an exopolysaccharide (EPS) depolymerase for treating bacterial infections. In some embodiments, the EPS depolymerase comprises alginate lyase. Also envisioned within the scope of the invention are compositions comprising one or more of the bacteriophages, methods for treating bacterial infections, and kits comprising the compositions described herein.
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公开(公告)号：US20230174954A1
公开(公告)日：2023-06-08
申请号：US17917543
申请日：2021-04-27
CPC分类号： C12N7/00 , A61K35/76 , A61P31/04 , A61K45/06 , C12N2795/10121 , C12N2795/10132 , C12N2795/10171 , C12N2795/10221 , C12N2795/10232 , C12N2795/10271
摘要： The present disclosure relates to bacteriophage and compositions capable of infecting and killing Pseudomonas, and use of the same for treating Pseudomonas, e.g. Pseudomonas aeruginosa, bacterial infections.
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公开(公告)号：US20240226205A1
公开(公告)日：2024-07-11
申请号：US18592379
申请日：2024-02-29
CPC分类号： A61K35/76 , A61K45/06 , A61P31/04 , C12N7/00 , C12N2795/10121 , C12N2795/10132 , C12N2795/10171 , C12N2795/10221 , C12N2795/10232 , C12N2795/10271
摘要： The present disclosure relates to bacteriophages and compositions capable of infecting and killing Pseudomonas, and use of the same for treating Pseudomonas, e.g. Pseudomonas aeruginosa, bacterial infections.
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