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公开(公告)号：US20230028487A1
公开(公告)日：2023-01-26
申请号：US17949866
申请日：2022-09-21
Inventor： Russell Witte , Hao Xin , Diego Martin
Abstract: A method and system capable of applying microwave therapy guided by thermoacoustic imaging and/or thermoacoustic thermometry is disclosed. The system includes a thermoacoustic imaging system and/or a thermoacoustic thermometry system that generate(s) a map of a region of interest; and a microwave therapy system that targets the region of interest using the map, and that applies the microwave therapy to the targeted region of interest. Treatment of the targeted region of interest may be employed by the microwave therapy system using real-time feedback from the thermoacoustic imaging system and/or the thermoacoustic thermometry system. Imaging and therapy may be automatically co-registered.
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公开(公告)号：US20190142513A1
公开(公告)日：2019-05-16
申请号：US16098624
申请日：2017-05-02
Inventor： Russell Witte , Hao Xin , Diego Martin
Abstract: A method and system capable of applying microwave therapy guided by thermoacoustic imaging and/or thermoacoustic thermometry is disclosed. The system includes a thermoacoustic imaging system and/or a thermoacoustic thermometry system that generate(s) a map of a region of interest; and a microwave therapy system that targets the region of interest using the 5 map, and that applies the microwave therapy to the targeted region of interest. Treatment of the targeted region of interest may be employed by the microwave therapy system using real-time feedback from the thermoacoustic imaging system and/or the thermoacoustic thermometry system. Imaging and therapy may be automatically co-registered.
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公开(公告)号：US10856938B2
公开(公告)日：2020-12-08
申请号：US16028020
申请日：2018-07-05
Inventor： Ikeotunye Royal Chinyere , Jen Watson Koevary , Jordan Lancaster , Steven Goldman , Russell Witte , Kyle Weigand
IPC: A61B18/14 , A61B5/0464 , A61B5/042 , A61B5/00 , A61B18/00
Abstract: Systems are provided for assessing the likelihood that a sample of cardiac tissue will spontaneously exhibit disordered electrical activity. These systems induce ventricular tachycardia or other disordered electrical activity in a sample of human and/or animal cardiac tissue either in vivo or in vitro. This system can be used to assess the ability of various pharmaceuticals, genetic modifications, electrical pacing, surgical ablation, or other therapeutic interventions to prevent or halt such disordered electrical activity. This system detects electrical activity from a plurality of points on the surface of the sample of cardiac tissue and generates one or more maps of monophasic action potential amplitude, monophasic action potential duration, local field amplitude, or other electrophysiological parameters of the cardiac tissue. These maps are then used to assess the likelihood that the sample will spontaneously exhibit disordered electrical activity and/or to assess the effect of a therapeutic intervention on that likelihood.
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