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公开(公告)号：US20240426793A1
公开(公告)日：2024-12-26
申请号：US18744883
申请日：2024-06-17
Applicant: AMGEN INC.
Inventor： Nicholas Anthony VECCHIARELLO , Venkatesh NATARAJAN , Andrew John MALONEY , Benjamin SMITH , Joseph Edward BASCONI
Abstract: Disclosed herein are methods for chromatography, including cleaning methods for chromatography medium that make use of a linear salt gradient. The disclosed methods may be used for frontal chromatography operations and for cleaning frontal chromatography media for reuse in biologics manufacturing.
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