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公开(公告)号：US20160304603A1
公开(公告)日：2016-10-20
申请号：US15150627
申请日：2016-05-10
Applicant: AMGEN INC.
Inventor： Jian WU , Nicole Sabo , Michael DE LA Cruz , Gregory Flynn
Abstract: The present invention relates to methods of modulating (e.g., reducing) the mannose content, particularly high-mannose content of recombinant glycoproteins.
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