公开(公告)号：US20160046625A1

公开(公告)日：2016-02-18

申请号：US14828928

申请日：2015-08-18

Applicant: AMGEN INC.

Inventor： Christiane M. Boezio ,  Alan C. Cheng ,  Deborah Choquette ,  Richard T. Lewis ,  Michele H. Potashman ,  Karina Romero ,  John C. Stellwagen ,  Douglas A. Whittington

IPC: C07D471/04 ,  C07D519/00 ,  C07D417/12 ,  C07D403/06 ,  C07D235/32 ,  C07D401/06

CPC classification number: C07D471/04 ,  C07D235/30 ,  C07D235/32 ,  C07D401/06 ,  C07D401/10 ,  C07D401/12 ,  C07D401/14 ,  C07D403/04 ,  C07D403/06 ,  C07D403/08 ,  C07D413/10 ,  C07D413/14 ,  C07D417/06 ,  C07D417/12 ,  C07D417/14 ,  C07D487/04 ,  C07D519/00

Abstract: Compounds of Formula (I) are useful inhibitors of anaplastic lymphoma kinase. Compounds of Formula (I) have the following structure: where the definitions of the variables are provided herein.