公开(公告)号：US20250009909A1

公开(公告)日：2025-01-09

申请号：US18780117

申请日：2024-07-22

Applicant: ALUME BIOSCIENCES, INC.

Inventor： Quyen NGUYEN ,  Michael WHITNEY

IPC: A61K49/00 ,  C07K7/06 ,  C07K7/08

Abstract: Methods for visualizing a ureter, including fluorescent visualization of a ureter, as well as other target tissues, during a surgical procedure, comprising administering to a subject a fluorescent conjugate comprising a peptide and a fluorescent moiety.

公开(公告)号：US20240207421A1

公开(公告)日：2024-06-27

申请号：US18254565

申请日：2021-12-03

Applicant: ALUME BIOSCIENCES, INC.

Inventor： Michael WHITNEY ,  Quyen NGUYEN

IPC: A61K47/64 ,  A61K41/00 ,  A61K49/00 ,  C12N15/10

CPC classification number: A61K47/64 ,  A61K41/0061 ,  A61K41/0071 ,  A61K41/0076 ,  A61K41/008 ,  A61K49/0056 ,  C12N15/1037

Abstract: The present disclosure provides nerve targeting peptides, including those comprising the amino acid sequence of any one of SEQ ID NOS: 1-710; conjugates comprising such nerve targeting peptides and a cargo molecule; compositions comprising said peptides and conjugates; and methods of said peptides and conjugates in surgical procedures and other applications.

公开(公告)号：US20230338585A1

公开(公告)日：2023-10-26

申请号：US18349833

申请日：2023-07-10

Applicant: ALUME BIOSCIENCES, INC.

Inventor： Quyen NGUYEN ,  Michael WHITNEY

IPC: A61K49/00

CPC classification number: A61K49/0056 ,  A61K49/0043

Abstract: Methods for visualizing a ureter, including fluorescent visualization of a ureter, as well as other target tissues, during a surgical procedure, comprising administering to a subject a fluorescent conjugate comprising a peptide and a fluorescent moiety.