公开(公告)号：US20150329832A1

公开(公告)日：2015-11-19

申请号：US14813374

申请日：2015-07-30

申请人： AJINOMOTO CO., INC.,

发明人： Sho SENDA ,  Tomomi YOSHIDA ,  Satoru OKAMOTO ,  Yoko KURIYAMA ,  Manabu KITAZAWA ,  lkue HARADA ,  Nao SUGIMOTO

IPC分类号： C12N5/074

摘要： Cultivating a pluripotent stem cell in a medium comprising at least one member selected from the group consisting of ethanolamine, an ethanolamine analog, and a pharmaceutically acceptable salt thereof, and which is substantially free of β-mercaptoethanol or contains β-mercaptoethanol at a concentration of not more than 9 μM, and the like, is effective for the proliferation of a pluripotent stem cell while maintaining an undifferentiated state.

摘要翻译： 在包含至少一种选自乙醇胺，乙醇胺类似物和其药学上可接受的盐的培养基中培养多能干细胞，其基本上不含β-巯基乙醇或含有β-巯基乙醇 不超过9μM的浓度等对多能干细胞的增殖有效，同时保持未分化状态。