公开(公告)号：US20230357300A1

公开(公告)日：2023-11-09

申请号：US18188101

申请日：2023-03-22

申请人： ADJUVANCE TECHNOLOGIES, INC.

发明人： Amanda CHAN ,  Jeffrey GARDNER ,  Lars NORDSTROEM ,  William WALKOWICZ ,  J Tyler MARTIN ,  Weidong ZHANG

IPC分类号： A61P31/20 ,  A61P31/04 ,  A61K39/02 ,  A61K39/09 ,  A61K39/29 ,  A61K39/08 ,  A61K39/39 ,  C07H13/08 ,  C07H1/08 ,  A61K39/00 ,  A61K39/05 ,  C07H15/18

CPC分类号： C07H1/08 ,  A61K39/0018 ,  A61K39/05 ,  A61K39/08 ,  A61K39/092 ,  A61K39/099 ,  A61K39/292 ,  A61K39/39 ,  A61P31/04 ,  A61P31/20 ,  C07H13/08 ,  C07H15/18 ,  A61K2039/55511 ,  A61K2039/55577 ,  A61K2039/6037

摘要： The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases.

公开(公告)号：US20210299237A1

公开(公告)日：2021-09-30

申请号：US16604867

申请日：2018-04-13

申请人： ADJUVANCE TECHNOLOGIES, INC.

发明人： Amanda CHAN ,  Jeffrey GARDNER ,  Lars NORDSTROEM ,  William WALKOWICZ ,  J Tyler MARTIN ,  Weidong Zhang

IPC分类号： A61K39/00 ,  C07H1/08 ,  C07H15/18 ,  A61K39/05 ,  A61K39/08 ,  A61K39/09 ,  A61K39/02 ,  A61K39/29 ,  A61K39/39 ,  A61P31/20 ,  A61P31/04

摘要： The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases.