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公开(公告)号：US11357870B2
公开(公告)日：2022-06-14
申请号：US17463262
申请日：2021-08-31
Applicant: 4D MOLECULAR THERAPEUTICS INC.
Inventor： David H. Kirn , Melissa A. Kotterman , Peter Francis
Abstract: The present disclosure provides codon optimized nucleotide sequences encoding human REP1, vectors, and host cells comprising codon optimized REP1 sequences, and methods of treating retinal disorders such as choroideremia comprising administering to the subject a codon optimized sequence encoding human REP1.
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Patent Agency Ranking
公开(公告)号：US20230158172A1
公开(公告)日：2023-05-25
申请号：US18052735
申请日：2022-11-04
Applicant: 4D MOLECULAR THERAPEUTICS INC.
Inventor： David H. Kirn , Melissa A. Kotterman , Peter Francis
CPC classification number: A61K48/0058 , C12N9/1085 , C12N15/86 , A61P27/02 , C12Y205/01059 , C12N2750/14143
Abstract: The present disclosure provides codon optimized nucleotide sequences encoding human REP1, vectors, and host cells comprising codon optimized REP1 sequences, and methods of treating retinal disorders such as choroideremia comprising administering to the subject a codon optimized sequence encoding human REP1.
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公开(公告)号：US20220290181A1
公开(公告)日：2022-09-15
申请号：US17825665
申请日：2022-05-26
Applicant: 4D MOLECULAR THERAPEUTICS INC.
Inventor： David H. Kirn , Melissa A. Kotterman , David Schaffer , Peter Francis
Abstract: The present disclosure provides codon optimized RPGRorf15 sequences, vectors, and host cells comprising codon optimized RPGRorf15 sequences, and methods of treating retinal disorders such as XLRP comprising administering to the subject a codon optimized RPGRorf15 sequence.
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公开(公告)号：US20240358859A1
公开(公告)日：2024-10-31
申请号：US18766963
申请日：2024-07-09
Applicant: 4D MOLECULAR THERAPEUTICS INC.
Inventor： David H. Kirn , Melissa A. Kotterman , Peter Francis
CPC classification number: A61K48/0058 , A61P27/02 , C12N9/1085 , C12N15/86 , C12Y205/01059 , C12N2750/14143
Abstract: The present disclosure provides codon optimized nucleotide sequences encoding human REP1, vectors, and host cells comprising codon optimized REP1 sequences, and methods of treating retinal disorders such as choroideremia comprising administering to the subject a codon optimized sequence encoding human REP1.
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公开(公告)号：US11345930B2
公开(公告)日：2022-05-31
申请号：US17461716
申请日：2021-08-30
Applicant: 4D MOLECULAR THERAPEUTICS INC.
Inventor： David H. Kirn , Melissa A. Kotterman , David Schaffer , Peter Francis
Abstract: The present disclosure provides codon optimized RPGRorf15 sequences, vectors, and host cells comprising codon optimized RPGRorf15 sequences, and methods of treating retinal disorders such as XLRP comprising administering to the subject a codon optimized RPGRorf15 sequence.
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公开(公告)号：US11524081B2
公开(公告)日：2022-12-13
申请号：US17740045
申请日：2022-05-09
Applicant: 4D MOLECULAR THERAPEUTICS INC.
Inventor： David H. Kirn , Melissa A. Kotterman , Peter Francis
Abstract: The present disclosure provides codon optimized nucleotide sequences encoding human REP1, vectors, and host cells comprising codon optimized REP1 sequences, and methods of treating retinal disorders such as choroideremia comprising administering to the subject a codon optimized sequence encoding human REP1.
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