Invention Grant
- Patent Title: Codon optimized REP1 genes and uses thereof
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Application No.: US17463262Application Date: 2021-08-31
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Publication No.: US11357870B2Publication Date: 2022-06-14
- Inventor: David H. Kirn , Melissa A. Kotterman , Peter Francis
- Applicant: 4D MOLECULAR THERAPEUTICS INC.
- Applicant Address: US CA Emeryville
- Assignee: 4D MOLECULAR THERAPEUTICS INC.
- Current Assignee: 4D MOLECULAR THERAPEUTICS INC.
- Current Assignee Address: US CA Emeryville
- Agency: Much Shelist, PC
- Agent Christopher M. Cabral
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C12N9/10 ; C12N15/86 ; A61P27/02

Abstract:
The present disclosure provides codon optimized nucleotide sequences encoding human REP1, vectors, and host cells comprising codon optimized REP1 sequences, and methods of treating retinal disorders such as choroideremia comprising administering to the subject a codon optimized sequence encoding human REP1.
Public/Granted literature
- US20220062438A1 CODON OPTIMIZED REP1 GENES AND USES THEREOF Public/Granted day:2022-03-03
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