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公开(公告)号：US20200268625A1
公开(公告)日：2020-08-27
申请号：US16871422
申请日：2020-05-11
发明人： Yizhong Wang , Tiffany T. Ton , Melinda B. Gustafson , Jennifer Post , Paul R. Klaiber , Carola A. Carrera Vidal , Joel D. Oxman
IPC分类号： A61K8/21 , A61K45/06 , A61K33/16 , A61K8/73 , A61K8/27 , A61C19/06 , A61K8/19 , A61K8/24 , A61K8/26 , A61K8/81 , A61Q11/00
摘要： An aqueous oral care fluoride treatment composition, a method of providing fluoride to a patient's tooth surface, and a method of reducing the incidence of dental caries, wherein the composition includes: 0.1 wt-% to 3.0 wt-% of a crosslinked poly acid having carboxylic acid side groups; a pharmaceutically acceptable buffer; 1.0 wt-% to 2.5 wt-% of sodium fluoride; 0.025 wt-% to 1.75 wt-% of a multivalent cation salt; and at least 60 wt-% water; wherein the weight percentages are based on the total weight of the aqueous composition.
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公开(公告)号：US20190099338A1
公开(公告)日：2019-04-04
申请号：US16148415
申请日：2018-10-01
发明人： Yizhong Wang , Tiffany T. Ton , Melinda B. Gustafson , Jennifer Post , Paul R. Klaiber , Carola A. Carrera Vidal , Joel D. Oxman
摘要： An aqueous oral care fluoride treatment composition, a method of providing fluoride to a patient's tooth surface, and a method of reducing the incidence of dental caries, wherein the composition includes: 0.1 wt-% to 3.0 wt-% of a crosslinked poly acid having carboxylic acid side groups; a pharmaceutically acceptable buffer; 1.0 wt-% to 2.5 wt-% of sodium fluoride; 0.025 wt-% to 1.75 wt-% of a multivalent cation salt; and at least 60 wt-% water; wherein the weight percentages are based on the total weight of the aqueous composition.
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公开(公告)号：US11337902B2
公开(公告)日：2022-05-24
申请号：US16871422
申请日：2020-05-11
发明人： Yizhong Wang , Tiffany T. Ton , Melinda B. Gustafson , Jennifer Post , Paul R. Klaiber , Carola A. Carrera Vidal , Joel D. Oxman
IPC分类号： A61K8/21 , A61K45/06 , A61K33/16 , A61K8/73 , A61K8/27 , A61C19/06 , A61K8/19 , A61K8/24 , A61K8/26 , A61K8/81 , A61Q11/00
摘要： An aqueous oral care fluoride treatment composition, a method of providing fluoride to a patient's tooth surface, and a method of reducing the incidence of dental caries, wherein the composition includes: 0.1 wt-% to 3.0 wt-% of a crosslinked poly acid having carboxylic acid side groups; a pharmaceutically acceptable buffer; 1.0 wt-% to 2.5 wt-% of sodium fluoride; 0.025 wt-% to 1.75 wt-% of a multivalent cation salt; and at least 60 wt-% water; wherein the weight percentages are based on the total weight of the aqueous composition.
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公开(公告)号：US10682300B2
公开(公告)日：2020-06-16
申请号：US16148415
申请日：2018-10-01
发明人： Yizhong Wang , Tiffany T. Ton , Melinda B. Gustafson , Jennifer Post , Paul R. Klaiber , Carola A. Carrera Vidal , Joel D. Oxman
IPC分类号： A61K8/21 , A61K45/06 , A61K33/16 , A61K8/73 , A61K8/27 , A61C19/06 , A61K8/19 , A61K8/24 , A61K8/26 , A61K8/81 , A61Q11/00
摘要： An aqueous oral care fluoride treatment composition, a method of providing fluoride to a patient's tooth surface, and a method of reducing the incidence of dental caries, wherein the composition includes: 0.1 wt-% to 3.0 wt-% of a crosslinked poly acid having carboxylic acid side groups; a pharmaceutically acceptable buffer; 1.0 wt-% to 2.5 wt-% of sodium fluoride; 0.025 wt-% to 1.75 wt-% of a multivalent cation salt; and at least 60 wt-% water; wherein the weight percentages are based on the total weight of the aqueous composition.
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公开(公告)号：US20190183621A1
公开(公告)日：2019-06-20
申请号：US16202340
申请日：2018-11-28
发明人： Bruce R. Broyles , Paul R. Klaiber , Jennifer Post
CPC分类号： A61C19/063 , A61K8/21 , A61K8/8147 , A61K2800/87 , A61Q11/00
摘要： A method of applying a dental treatment composition to a patient's teeth, including selecting a dental treatment composition, applying the dental treatment composition to a surface of at least one tooth of the patient; and applying pressurized gas on the dental treatment composition to spread the dental treatment composition smoothly across the surface of the tooth.
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