公开(公告)号：US06656328B2

公开(公告)日：2003-12-02

申请号：US10070877

申请日：2002-03-05

申请人： Syunsaku Kato ,  Daisuke Suzuki ,  Yoshiko Seo

发明人： Syunsaku Kato ,  Daisuke Suzuki ,  Yoshiko Seo

IPC分类号： C07C3700

CPC分类号： C07J1/0077 ,  C07B41/02 ,  C07C37/055 ,  C07C2603/42 ,  C07D213/69 ,  C07D309/30 ,  C07J1/00 ,  C07J1/0055 ,  C07J1/007 ,  Y02P20/55 ,  C07C39/14 ,  C07C39/12 ,  C07C39/10

摘要： A process for preparing a polyhydric alcohol according to the invention comprises subjecting a polyhydric alcohol compound having protected hydroxy group(s) to microwave irradiation in the presence of basic compound(s) or acid(s) having an acid dissociation exponent (pKa) of −8 to 3 at 25° C. to remove the protecting groups of the hydroxy group of the polyhydric alcohol compound. The invention can provide an industrially advantageous process for preparing polyhydric alcohols by readily removing protecting group(s) from protected hydroxy group(s) of polyhydric alcohol compounds.

公开(公告)号：US06887992B2

公开(公告)日：2005-05-03

申请号：US10679451

申请日：2003-10-07

申请人： Takashi Moriyoshi ,  Yasuhiro Uosaki ,  Yutaka Kameyama ,  Daisuke Suzuki ,  Yoshiko Seo

发明人： Takashi Moriyoshi ,  Yasuhiro Uosaki ,  Yutaka Kameyama ,  Daisuke Suzuki ,  Yoshiko Seo

IPC分类号： C07D501/00 ,  C07D501/12 ,  C07D501/24 ,  C07D501/30

CPC分类号： C07D501/00 ,  Y02P20/544

摘要： A 3-cephem derivative crystal which is a clathrate compound comprising p-methoxybenzyl ester of 7-phenylacetamide-3-formyl-3-cephem-4-carboxylic acid and dimethylformamide and a process for preparing the 3-cephem derivative crystal.

摘要翻译： 作为包含7-苯基乙酰胺-3-甲酰基-3-头孢烯-4-羧酸和二甲基甲酰胺的对甲氧基苄基酯的包合物化合物的3-头孢烯衍生物结晶和制备3-头孢烯衍生物结晶的方法。