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1.发明授权公开(公告)号：US06869414B2
公开(公告)日：2005-03-22
申请号：US10105087
申请日：2002-03-22
CPC分类号： A61M25/0147 , A61M25/0041 , A61M25/0138 , A61M25/0152 , A61M2025/0161 , A61M2025/0163
摘要： A catheter employs a pre-formed distal end and a proximal deflection mechanism for steering the catheter. A shaped member extends from a shaped region of the catheter sheath to at least a portion of an anchor region. A steering ribbon extends from a proximal region of the sheath and passes within at least a portion of the anchor region. A distal end of the steering ribbon is joined with a proximal portion of the shaped member. At least one steering tendon is disposed within the sheath and has a first end attached at the anchor region and a second end located at the proximal region of the sheath. Movement of the steering tendon in a proximal direction causes the deflection region to deflect relative to the longitudinal axis of the catheter while the shape of shaped region of the sheath is substantially maintained.
摘要翻译： 导管采用预先形成的远端和用于转导导管的近端偏转机构。 成形构件从导管护套的成形区域延伸到锚定区域的至少一部分。 转向带从护套的近侧区域延伸并且在锚定区域的至少一部分内通过。 转向带的远端与成形构件的近端部分连接。 至少一个转向筋设置在护套内并且具有附接在锚定区域处的第一端和位于护套的近侧区域处的第二端。 转向腱在近端方向的移动导致偏转区域相对于导管的纵向轴线偏转，同时护套的成形区域的形状基本上保持。
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公开(公告)号：US06652517B1
公开(公告)日：2003-11-25
申请号：US09558478
申请日：2000-04-25
IPC分类号： A61B1818
CPC分类号： A61B18/1492 , A61B2017/00243 , A61B2017/22038 , A61B2017/22068 , A61B2018/00214 , A61B2018/0022 , A61B2018/00261 , A61B2018/00285 , A61B2018/00375 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/124 , A61B2018/1407 , A61B2018/1435
摘要： A cardiac ablation apparatus for producing a circumferential ablation that electrically isolates a heart chamber wall portion from vessel such as a pulmonary vein extending into a wall portion comprises (a) an elongate centering catheter having a distal end portion; (b) an expandable centering element connected to the centering catheter distal end portion and configured for positioning within the vessel when in a retracted configuration, and for securing the elongate centering catheter in a substantially axially aligned position with respect to the vessel when the centering element is in an expanded configuration; (c) an ablation catheter slidably connected to the centering catheter the ablation element having a distal end portion, and (d) an expandable ablation element connected to the ablation catheter distal end portion.
摘要翻译： 一种心脏消融装置，用于产生将心室壁部分与血管延伸到壁部分中的肺静脉电隔离的周缘消融，包括：（a）具有远端部分的细长定心导管; （b）连接到定心导管远端部分并且构造成当处于缩回构型时定位在容器内的可扩张定心元件，并且当中心元件 处于扩展配置; （c）消融导管，其可滑动地连接到所述定心导管，所述消融元件具有远端部分，以及（d）可扩展的消融元件，其连接到所述消融导管远端部分。
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3.发明授权公开(公告)号：US06592581B2
公开(公告)日：2003-07-15
申请号：US09746721
申请日：2000-12-22
申请人： Wade A. Bowe
发明人： Wade A. Bowe
IPC分类号： A61B1818
CPC分类号： A61M25/0041 , A61B2017/00053 , A61B2017/00057 , A61B2017/00243 , A61B2017/00867 , A61M25/0133 , A61N1/056
摘要： A wire housed within a sheath is formed of a shape-retentive and resilient material having a curved shape at its distal-end region resulting in the catheter sheath having the curved shape. The catheter sheath also has an axially oriented tendon for causing deflection of the distal-end region. A movable outer sleeve surrounds the sheath and conforms the portion of the wire positioned within the outer sleeve to the shape of the outer sleeve. Upon relative displacement of the sheath and the outer sleeve a portion of the sheath extends beyond the outer sleeve and resumes its preformed curved distal shape thereby forcing the catheter distal-end region into the same curved shape. The operator may adjust the relative positions of the sheath and outer sleeve to changes the shape of the distal-end region. The operator may also axially move the tendon to adjust the radius or curvature of the distal-end region.
摘要翻译： 容纳在护套内的线由在其远端区域具有弯曲形状的形状保持性和弹性材料形成，导致导管护套具有弯曲形状。 导管鞘还具有轴向定向的腱，用于引起远端区域的偏转。 可移动外套筒围绕护套并使位于外套筒内的线的部分符合外套筒的形状。 在护套和外套筒的相对位移时，护套的一部分延伸超过外套筒并恢复其预先形成的弯曲远端形状，从而迫使导管远端区域变成相同的弯曲形状。 操作者可以调节护套和外套筒的相对位置以改变远端区域的形状。 操作者还可以轴向移动肌腱以调节远端区域的半径或曲率。
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公开(公告)号：US5681280A
公开(公告)日：1997-10-28
申请号：US434003
申请日：1995-05-02
IPC分类号： A61B18/14 , A61M25/01 , A61M25/092
CPC分类号： A61M25/0147 , A61B18/1492 , A61M25/0136 , A61B2018/00214 , A61B2018/00916 , A61M2025/015
摘要： A steerable catheter comprising a resilient deflectable body member having an expandable electrode array at the distal end thereof, and a manipulation handle attached to the proximal end of the body member, the handle including an array deployment device. A mandrel is movable through the shaft of the catheter by control movements at the handle to deploy the array or collapse the array as selected. A displacement compensation system is operatively connected to the mandrel such that when the array is expanded, the compensation system biases the mandrel so keep the array expanded, even during instances of deflection of the distal end. Similarly, the displacement compensation system biases the mandrel to keep the array collapsed when that configuration is selected, even during instances of straightening of the catheter. The displacement compensation system also compensates for overturning the control device in the handle to protect the array and deployment systems.
摘要翻译： 一种可导向的导管，其包括在其远端处具有可扩张电极阵列的弹性可偏转主体构件和附接到主体构件的近端的操纵手柄，所述手柄包括阵列展开装置。 心轴可以通过导管的轴移动，通过手柄处的控制运动来部署阵列或者按选择折叠阵列。 位移补偿系统可操作地连接到心轴，使得当阵列膨胀时，补偿系统偏压心轴，使得即使在远端的偏转的实例期间也使阵列扩张。 类似地，即使在导尿管矫正的情况下，位移补偿系统也会偏心心轴以保持阵列在选择该构型时收缩。 位移补偿系统还补偿了手柄中的控制装置的翻转，以保护阵列和展开系统。
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公开(公告)号：US20120095479A1
公开(公告)日：2012-04-19
申请号：US13333783
申请日：2011-12-21
IPC分类号： A61B19/00
摘要： The invention provides an apparatus having a tubular member for receiving an endocardial lead implanted within a patient's body. Disposed generally at a distal end of the tubular member is at least one blade or cutting surface. An adjustment mechanism moves the blade between retracted and extended positions to engage the cutting surface with the endocardial lead to cut the lead. Once severed, the cut portion of the lead remains within an inner channel of the tubular member and the apparatus and cut portion of the lead are removed from within the patient. Various embodiments include the blade pivotally connected to the distal end of the tubular member and activated by a wire adjustment mechanism. Others include a metallic wire for slicing through the lead. Still others include a pneumatically actuated adjustment mechanism that inflates to move the blade and engage the cutting surface with the lead.
摘要翻译： 本发明提供了一种具有用于接收植入患者体内的心内膜的管状构件的装置。 通常在管状构件的远端处设置有至少一个刀片或切割表面。 调节机构使叶片在缩回位置和伸展位置之间移动，以使切割表面与心内膜导线接合以切割引线。 一旦切断，引线的切割部分保留在管状部件的内部通道内，并且引线的设备和切割部分从患者体内移除。 各种实施例包括枢转地连接到管状构件的远端并由线调节机构启动的刀片。 其他的包括用于通过引线切片的金属线。 还有一些还包括气动调节机构，其膨胀以移动叶片并且与导线接合切割表面。
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公开(公告)号：US07209783B2
公开(公告)日：2007-04-24
申请号：US10123897
申请日：2002-04-16
申请人： Chris Fellows , Wade A. Bowe , David S. Wood
发明人： Chris Fellows , Wade A. Bowe , David S. Wood
CPC分类号： A61F2/82 , A61B18/1492 , A61B2018/00214 , A61B2018/00375
摘要： An apparatus and method for treating atrial fibrillation with ablation therapy in which a stent is deployed within a pulmonary vein and tissue surrounding the stent is ablated with radiofrequency energy to stop discharges from ectopic foci in the vein from reaching the left atrium. The deployed stent can then be left in place to prevent stenosis of the vein as well as allowing repeat ablation procedures as needed.
摘要翻译： 一种用消融治疗来治疗房颤的装置和方法，其中支架被部署在肺静脉内并且支架周围的组织被射频能量消融以阻止静脉中异位灶的排出物到达左心房。 然后将部署的支架置于适当位置以防止静脉狭窄以及根据需要允许重复消融手术。
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7.发明授权Ablation and high-resolution mapping catheter system for pulmonary vein foci elimination 有权消融和高分辨率导管系统用于肺静脉消融公开(公告)号：US06771996B2
公开(公告)日：2004-08-03
申请号：US09866049
申请日：2001-05-24
申请人： Wade A. Bowe , Jeffrey A. Hall
发明人： Wade A. Bowe , Jeffrey A. Hall
IPC分类号： A61B504
CPC分类号： A61B18/1492 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00375 , A61B2018/0091 , A61B2018/126 , A61B2018/1407 , A61B2018/1467
摘要： A catheter system includes an outer catheter having a lumen and an inner catheter sized to fit within and slide through the lumen of the outer catheter. Both catheters may be introduced into an anatomical site through a single introduction path. At the distal-end region of each catheter is an electrode system. One electrode system is for mapping the site; the other is for ablating the site. The distal-end regions of one or both of the catheters may be linear shaped, circular shaped, or radially expandable. When the catheter system is deployed the electrode systems carried by the distal-end regions of the mapping catheter and the ablation catheter are movable relative to each other and tend to lie in planes substantially parallel to each other. Another catheter system includes two separate electrode systems on a single expandable member shaped so that both electrode systems come in contact with separate sites.
摘要翻译： 导管系统包括具有内腔和内导管的外导管，其尺寸适于安装在外导管的内腔内并通过外导管滑动。 两个导管可以通过单个引入路径被引入解剖部位。 在每个导管的远端区域是电极系统。 一个电极系统用于映射现场; 另一个是为了烧毁网站。 一个或两个导管的远端区域可以是直线形，圆形或径向可扩张的。 当部署导管系统时，由映射导管和消融导管的远端区域承载的电极系统可相对于彼此移动并且倾向于位于彼此基本平行的平面中。 另一种导管系统包括在单个可扩张构件上的两个单独的电极系统，其形状使得两个电极系统与分开的位置接触。
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公开(公告)号：US06312425B1
公开(公告)日：2001-11-06
申请号：US09515382
申请日：2000-02-29
IPC分类号： A61B1804
CPC分类号： A61N1/06 , A61B18/1492 , A61B2017/00097 , A61B2017/00101 , A61B2018/00797 , A61B2018/00821
摘要： A tip electrode for an ablation catheter mounted at the distal tip of an elongated catheter body member has a distal-end region and a proximal-end region. A tip thermal sensor is located at or near the apex of the distal-end region and one or more side thermal sensors are located near the surface of the proximal-end region. The electrode is preferably an assembly formed from a hollow dome-shaped shell with a core disposed within the shell. The side thermal sensor wires are electrically connected inside the shell and the core has a longitudinal channel for the side thermal sensor wires welded to the shell. The shell also preferably has a pocket in the apex of the shell, and the end thermal sensor wires pass through the core to the apex of the shell. Spaces between the shell and the core can be filled with epoxy resin. Alternatively, the electrode is formed of a solid metal having a plurality of bores for positioning thermal sensors at the tip and near the surface of the electrode.
摘要翻译： 安装在细长导管本体构件的远端的消融导管的尖端电极具有远端区域和近端区域。 尖端热传感器位于远端区域的顶点处或附近，并且一个或多个侧面热传感器位于近端区域的表面附近。 电极优选是由具有设置在壳体内的芯的中空圆顶形壳体形成的组件。 侧面热传感器线电连接在壳体内部，并且芯部具有用于焊接到壳体的侧部热传感器线的纵向通道。 外壳还优选地在壳的顶点具有凹穴，并且端部热传感器线穿过芯到壳的顶点。 外壳和芯之间的空间可以填充环氧树脂。 或者，电极由具有多个孔的固体金属形成，用于在电极的顶端和附近定位热传感器。
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公开(公告)号：US06270496B1
公开(公告)日：2001-08-07
申请号：US09516280
申请日：2000-03-01
IPC分类号： A61B1818
CPC分类号： B82Y15/00 , A61B2017/00053 , A61B2017/00057 , A61B2017/00243 , A61B2017/00867 , A61M25/0041 , A61M25/0147 , A61M25/0152 , A61M2025/0161 , A61N1/056
摘要： A catheter has a stylet formed of a shape-retentive and resilient material having a preformed curved shape at its distal end resulting in the catheter sheath having the preformed curved shape. The catheter sheath has a plurality of electrodes at its distal end for contacting selected biological tissue for imparting ablation energy thereto. The catheter sheath also has an axially mounted tendon for causing deflection of the distal end. The stylet material permits straightening the catheter sheath during insertion into the patient and advancing the electrodes to the target tissue. Upon removal of the straightening forces, such as by entry into a chamber of the heart, the stylet material resumes its preformed curved distal shape thereby forcing the catheter distal end with the electrodes into the same preformed curved shape. The operator may place the curved distal end into contact with the target tissue and axially move the tendon as desired to gain greater control over the bend in the distal end of the catheter sheath to adjust the radius of curvature of the distal end to obtain greater contact of the electrodes with the heart tissue. Preferably, the stylet is formed of nitinol.
摘要翻译： 导管具有由形状保持性和弹性材料形成的探针，其在其远端处具有预成型的弯曲形状，导致导管护套具有预成型的弯曲形状。 导管鞘在其远端具有多个电极，用于接触选定的生物组织以向其施加消融能量。 导管护套还具有轴向安装的腱，用于引起远端的偏转。 探针材料允许在插入患者期间矫正导管鞘，并将电极推进到靶组织。 在去除矫直力时，例如通过进入心脏室，探针材料恢复其预先形成的弯曲远端形状，从而迫使导管远端与电极形成相同的预成形弯曲形状。 操作者可以将弯曲的远端放置成与目标组织接触，并根据需要轴向移动肌腱以获得对导管套管远端的弯曲部的更大控制，以调节远端的曲率半径以获得更大的接触 的电极与心脏组织。 探针最好由镍钛诺形成。
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公开(公告)号：US6146381A
公开(公告)日：2000-11-14
申请号：US73395
申请日：1998-05-05
CPC分类号： A61M25/0041 , A61B2017/00053 , A61B2017/00243 , A61B2017/00867 , A61M25/0147 , A61M25/0152 , A61N1/056
摘要： A catheter having a preformed distal shape for positioning a plurality of electrodes at a selected biological site includes a sheath having a preformed bend in the distal end region to distribute axial forces applied, in the distal direction, to the distal end region over a surface area of the distal end region proximal the distal tip. Also included in the catheter sheath is a stylet formed of a material capable of retaining a shape with the distal end of the stylet shaped in the preformed bend. Preferably, the preformed bend is approximately 45 degrees. Axial forces applied to the catheter are deflected to cause bowing of the catheter so that a larger surface area of the catheter contacts the tissue, rather than the smaller surface area of the distal tip. In other aspects, the portion of the sheath coincident with the preformed bend has a lower durometer, the stylet is more flexible by having a reduced diameter and the electrodes are located proximal to the preformed bend.
摘要翻译： 具有用于在选定的生物部位定位多个电极的预形成的远端形状的导管包括在远端区域中具有预成型弯曲的护套，用于将远端方向上施加的轴向力分布在表面区域上的远端区域 的远端区域。 还包括在导管鞘中的探针是由能够保持形状的材料形成的探针，所述探针的形状与预成形弯曲部中形状的探针的远端相连。 优选地，预成形弯曲部约为45度。 施加到导管的轴向力被偏转以引起导管弯曲，使得导管的较大表面积接触组织，而不是远端尖端的较小表面积。 在其他方面，护套与预成形弯曲部重合的部分具有较低的硬度，通过具有减小的直径并且电极位于预先形成的弯曲部的近侧，探针更灵活。
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