公开(公告)号：US4606912A

公开(公告)日：1986-08-19

申请号：US415970

申请日：1982-09-08

Applicant: Michael A. Rudy ,  Vincent F. Lisanti

Inventor： Michael A. Rudy ,  Vincent F. Lisanti

IPC: A61K8/19 ,  A61K8/24 ,  A61K8/44 ,  A61Q11/00 ,  A61K7/16 ,  A61K7/18 ,  A61K7/22 ,  A61K33/16

CPC classification number: A61Q11/00 ,  A61K8/19 ,  A61K8/24 ,  A61K8/44 ,  A61K2800/51

Abstract: A solutions for optimizing the environmental conditions within the human oral cavity is disclosed which enhances the functioning of cells of the oral cavity and promotes remineralization of teeth. These solutions are effective in treating and preventing caries and periodontal disease and reducing mouth odor and are easily and safely used by the lay population. A method of making the solutions which totally prevents the formation of calcium phosphate crystals, for example hydroxyapatite, is disclosed.

Abstract translation: 公开了一种用于优化人体口腔内环境条件的解决方案，其增强口腔细胞的功能并促进牙齿的再矿化。 这些解决方案有效治疗和预防龋齿和牙周病，并减少口臭，并且易于安全使用。 公开了制备完全防止磷酸钙晶体形成的溶液的方法，例如羟基磷灰石。

公开(公告)号：US4610873A

公开(公告)日：1986-09-09

申请号：US624812

申请日：1984-06-26

Applicant: Michael A. Rudy ,  Vincent F. Lisanti

Inventor： Michael A. Rudy ,  Vincent F. Lisanti

IPC: A61K8/19 ,  A61K8/24 ,  A61K8/44 ,  A61Q11/00 ,  A61K7/16 ,  A61K7/18

CPC classification number: A61Q11/00 ,  A61K8/19 ,  A61K8/24 ,  A61K8/44 ,  A61K2800/51

Abstract: A composition and method of making aqueous compositions which totally prevents the formation of calcium phosphate crystals, for example hydroxyapatite.

Abstract translation: 制备完全防止磷酸钙晶体形成的含水组合物的组合物和方法，例如羟基磷灰石。

公开(公告)号：US4024237A

公开(公告)日：1977-05-17

申请号：US601849

申请日：1975-08-04

Applicant: Bertram Eichel ,  Vincent F. Lisanti

Inventor： Bertram Eichel ,  Vincent F. Lisanti

IPC: A61K8/19 ,  A61K8/24 ,  A61K8/365 ,  A61K8/60 ,  A61K8/73 ,  A61Q11/00 ,  A61K7/16 ,  A61K7/20 ,  A61K7/24

CPC classification number: A61K8/19 ,  A61K8/24 ,  A61K8/365 ,  A61K8/60 ,  A61K8/73 ,  A61K8/735 ,  A61Q11/00 ,  Y10S514/801

Abstract: Novel compositions for establishing environmental conditions in the human oral cavity for maintaining healthy, functional oral leucocytes, said compositions comprising a non-toxic mixture of effective amounts of: (1) at least one compound for maintaining a colloidal and viscous environment within the oral cavity which favors and promotes oral leucocyte locomotion, phagocytosis and bacterial kill; (2) at least one compound providing and maintaining a balanced ionic environment which favors and promotes locomotion, phagocytosis and bacterial kill; (3) at least one compound providing a source of energy for said oral leucocytes; and (4) at least one compound for maintaining substantially a physiological pH to promote leucocyte functions while avoiding other tissue and cell injury; and novel products and processes employing the same.

Abstract translation: 用于在人口腔内建立用于维持健康的功能性口服白细胞的环境条件的新型组合物，所述组合物包含有效量的无毒混合物：（1）至少一种用于在口腔内维持胶体和粘稠环境的化合物 有利于促进口白血球运动，吞噬和细菌杀伤; （2）提供和保持平衡离子环境的至少一种化合物有利于和促进运动，吞噬作用和细菌杀伤; （3）至少一种为所述口服白细胞提供能量源的化合物; 和（4）至少一种用于维持基本上生理pH以促进白细胞功能同时避免其他组织和细胞损伤的化合物; 以及采用该产品和方法的新产品和方法。