公开(公告)号：US06215029B1

公开(公告)日：2001-04-10

申请号：US09328744

申请日：1999-06-09

Applicant: Urs Burckhardt ,  Armando Di Teodoro ,  Werner Hölzl ,  Dieter Reinehr ,  Rudolf Zink ,  Hanspeter Sauter ,  Uwe Gronde

Inventor： Urs Burckhardt ,  Armando Di Teodoro ,  Werner Hölzl ,  Dieter Reinehr ,  Rudolf Zink ,  Hanspeter Sauter ,  Uwe Gronde

IPC: C07C4101

CPC classification number: C07C43/295 ,  C07C49/84 ,  C07C67/42 ,  C07C69/017 ,  C07C69/65 ,  C07C69/63

Abstract: A process for the preparation of halohydroxydiphenyl compounds useful for protecting organic materials and articles from microorganisms, of the formula by acylation of a halogenated benzene compound (first stage), etherification of the acylated compound with a halogenated phenol compound (second stage), oxidation of the etherified compound (third stage) and hydrolysis of the oxidized compound in a fourth stage, according to the following reaction scheme: in which R1 and R2 independently of one another are F, Cl or Br; R3 and R4 independently of one another are hydrogen; or C1-C4alkyl; m is 1 to 3; and n is 1 or 2.

Abstract translation: 用于制备用于保护有机材料和制品免受微生物的卤代羟基联苯化合物的制备方法，卤化苯化合物的制备酰化（第一阶段），酰化化合物与卤化酚化合物的醚化（第二阶段） 根据以下反应方案，第四阶段的醚化化合物（第三阶段）和氧化化合物的水解：其中R1和R2彼此独立地为F，Cl或Br; R 3和R 4彼此独立地是氢; 或C 1 -C 4烷基; m为1〜3; n为1或2。