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    DEVICE AND METHOD FOR INTERFACING TWO SEPARATION TECHNIQUES
    2.
    发明申请
    DEVICE AND METHOD FOR INTERFACING TWO SEPARATION TECHNIQUES 审中-公开

    公开(公告)号：US20200209124A1

    公开(公告)日：2020-07-02

    申请号：US16614961

    申请日：2018-05-21

    Applicant: UNIVERSITY OF TASMANIA

    Inventor： Elisenda Fornells Vernet ,  Michael Charles Breadmore

    IPC: G01N1/40 ,  G01N30/46 ,  G01N30/12 ,  B01D61/36

    Abstract: The present invention relates to an evaporative membrane concentration device adapted to interface two liquid flow processes, such as two low or high resolution separation techniques or a low or high resolution separation technique and a liquid flow detection technique. For example, the two liquid flow processes may be a liquid chromatography technique and a liquid flow detection technique or a multi-dimensional separation technique, for example, two dimensional liquid chromatography (LC×LC) or solvent extraction, such as liquid-liquid extraction or solid phase extraction, with a liquid chromatography technique (LLE or SPE-LC). Methods of using the device and separation and/or chromatographic methods using the device are also described.

    Method, apparatus and system for automatically controlling inspired oxygen delivery
    4.
    发明授权
    Method, apparatus and system for automatically controlling inspired oxygen delivery 有权

    公开(公告)号：US11135384B2

    公开(公告)日：2021-10-05

    申请号：US15774946

    申请日：2016-11-10

    Applicant: University of Tasmania

    Inventor： Timothy John Gale ,  Peter Anderson Dargaville

    IPC: A61M16/00 ,  A61M16/12 ,  A61B5/00 ,  A61B5/083 ,  A61B5/1455 ,  A61B5/08 ,  G16H40/63 ,  G16H20/40

    Abstract: Provided herein is a method for automatically controlling inspired oxygen delivery, including: receiving signals representing a plurality of input oxygen saturation (SpO2) values for a patient; generating control values based on the input SpO2 values and a target SpO2 value; and generating output inspired oxygen concentration (FiO2) values based on the control values and reference inspired oxygen concentration (rFiO2) values; wherein the control values include: immediate control values, generated based on the input SpO2 values, the target SpO2 value, and an immediate gain coefficient; accumulation control values, generated based on the input SpO2 values, the target SpO2 value, and an accumulation gain coefficient; and predictive control values, generated based on the input SpO2 values, the target SpO2 value, and a predictive gain coefficient; wherein the immediate gain coefficient is determined based on the rFiO2 value; and wherein a non-linear compensation weighting is applied to the accumulation control value based on a predetermined non-linear relationship between partial pressure of arterial oxygen (PaO2) and SpO2.

    Metallothionein-Derived Peptide Fragments
    6.
    发明申请
    Metallothionein-Derived Peptide Fragments 有权
    金属硫蛋白衍生肽片段

    公开(公告)号：US20140179614A1

    公开(公告)日：2014-06-26

    申请号：US14086233

    申请日：2013-11-21

    Applicant: University of Tasmania

    Inventor： Vladimir Berezin ,  Elisabeth Bock ,  Milena Penkowa

    IPC: C07K7/08

    CPC classification number: C07K14/825 ,  A61K38/00 ,  C07K7/08

    Abstract: The present invention relates to neural cell survival, differentiation and proliferation promoting peptide fragments derived from metallothioneins (MT), pharmaceutical compositions comprising said peptide fragments and uses thereof for treatment of diseases and conditions where the effects of stimulating neural cell proliferation, differentiation and/or survival, and/or stimulating neural plasticity associated with learning and memory are beneficial for treatment.

    Abstract translation: 本发明涉及来自金属硫蛋白（MT）的神经细胞存活，分化和增殖促进肽片段，包含所述肽片段的药物组合物及其用于治疗刺激神经细胞增殖，分化和/或 生存和/或刺激与学习和记忆相关的神经可塑性有益于治疗。

    Liquid-liquid mixing device suitable for sample preparation by liquid-liquid extraction
    7.
    发明授权
    Liquid-liquid mixing device suitable for sample preparation by liquid-liquid extraction 有权

    公开(公告)号：US11590463B2

    公开(公告)日：2023-02-28

    申请号：US16626212

    申请日：2018-06-28

    Applicant: University of Tasmania

    Inventor： Robert Shellie ,  Masoomeh Tehrani Rokh ,  Marcel Van Den Bronk

    IPC: B01F31/441 ,  B01F23/40 ,  G01N1/38 ,  B01F23/43 ,  B01F23/451 ,  B01F35/75

    Abstract: A liquid-liquid mixing device (10, 210) includes a barrel (20, 220) with a liquid port (23) at or adjacent one end. A plunger assembly (30) is reciprocably moveable along an axis in the barrel (20, 220) and includes a seal member (31, 231) and an agitator (50, 250). The seal member (31, 231) is in sealingly slidable engagement with the internal wall of the barrel (20, 220) to define a variable volume chamber (24, 224) therein in communication with the liquid port. The agitator (50, 250) is reciprocably moveable in the variable volume chamber (24, 224), which agitator (50, 250) includes one or more end to end passages (54) through which liquid in the chamber (24, 224) is forced as the agitator (250) reciprocates in the chamber (24, 224). The device (10) also includes a mode selector mechanism (60, 28, 46, 64, 65, 90, 92, 94, 96) for selection between at least two modes of operation for the plunger assembly, wherein the mode selector mechanism (60, 28, 46, 64, 65, 90, 92, 94, 96) is adjustable between two or more modes whereby movement of the plunger assembly (30) effects either movement of the agitator (50, 250) with the seal member (31, 231) or movement of the agitator (50, 250) relative to the seal member (31, 231), depending on the selected mode.

    Liquid collection device
    8.
    发明授权
    Liquid collection device 有权

    公开(公告)号：US11278225B2

    公开(公告)日：2022-03-22

    申请号：US15751664

    申请日：2016-08-12

    Applicant: University of Tasmania

    Inventor： David Charles Bailey ,  Andrew Gooley ,  Florian Germain Lapierre ,  David John Melville ,  Rod Anthony Wiebenga ,  Chau Hoang Thanh Nguyen ,  Eugen Meyer

    IPC: A61B5/15 ,  A61B5/151 ,  G01N1/02 ,  A61B10/00

    Abstract: A pen format liquid collection device includes an elongate generally tubular housing (12, 112, 212, 312) able to be held by hand and having an opening at one end, and at least one liquid take-up element (30, 130, 230, 330) mounted in the housing so as to be positioned or positionable to project at the opening, the at least one liquid take-up element then further postionable by hand manipulation of the housing to contact a volume of liquid to thereby take-up a sample of the liquid to be analysed. At least one retention element (230a, 330a) is supported in the housing. The at least one liquid take-up element and the at least one retention element are arranged whereby they are relatively movable into contact, and the at least one retention element is adapted on contact to in turn take-up the sample and retain the sample or a component thereof for in situ analysis or later recovery while protected within the housing. The liquid take-up element is preferably a capillary.

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