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    Method and system for determining treatment plans
    1.
    发明授权
    Method and system for determining treatment plans 有权
    治疗方案的确定方法和系统

    公开(公告)号：US08688618B2

    公开(公告)日：2014-04-01

    申请号：US12820852

    申请日：2010-06-22

    Applicant: Todd R. McNutt ,  Russell H. Taylor ,  Michael Kazhdan ,  Binbin Wu ,  Patricio Simari

    Inventor： Todd R. McNutt ,  Russell H. Taylor ,  Michael Kazhdan ,  Binbin Wu ,  Patricio Simari

    IPC: G06F17/00 ,  G06N7/04

    CPC classification number: G06N5/02 ,  A61N2005/1041 ,  G06F19/00 ,  G06F19/3481 ,  G16H50/70

    Abstract: A system and method for determining at least one new treatment plan for at least one new patient, comprising: providing at least one representation of the at least one new patient's at least one organ at risk relative to at least one target; searching for at least one prior treatment plan for at least one prior patient with at least one similar representation; and reviewing the at least one prior treatment plan for the at least one prior patient in order to determine whether the at least one new treatment plan can be improved based on information in the at least one prior treatment plan.

    Abstract translation: 一种用于确定至少一个新患者的至少一个新的治疗计划的系统和方法，包括：提供所述至少一个新患者至少一个相对于至少一个靶标的风险的器官的至少一个表示; 为至少一个具有至少一个类似表示的先前患者寻找至少一个先前的治疗计划; 以及审查所述至少一个先前患者的至少一个先前治疗计划，以便基于所述至少一个以前的治疗计划中的信息确定是否可以改善所述至少一个新的治疗计划。

    Manual tools for model based image segmentation
    2.
    发明授权
    Manual tools for model based image segmentation 有权
    用于基于模型的图像分割的手动工具

    公开(公告)号：US07796790B2

    公开(公告)日：2010-09-14

    申请号：US10595357

    申请日：2004-10-06

    Applicant: Todd R. McNutt ,  Michael Kaus ,  Vladimir Pekar

    Inventor： Todd R. McNutt ,  Michael Kaus ,  Vladimir Pekar

    IPC: G06K9/00 ,  G06K9/34 ,  G06K9/46

    CPC classification number: G06T19/00 ,  G06K9/209 ,  G06K9/34 ,  G06K2009/366 ,  G06K2209/05 ,  G06T7/11 ,  G06T7/12 ,  G06T7/149 ,  G06T2200/24 ,  G06T2207/10081 ,  G06T2207/30004 ,  G06T2219/2021

    Abstract: A scanner (18) acquires images of a subject. A 3D model (52) of an organ is selected from an organ model database (50) and dropped over an image of an actual organ. A best fitting means (62) globally scales, translates and/or rotates the model (52) to best fit the actual organ represented by the image. A user uses a mouse (38) to use a set of manual tools (68) to segment and manipulate the model (52)1:o match the image data. The set of tools (68) includes: a Gaussian tool (72) for deforming a surface portion of the model along a Gaussian curve, a spherical push tool (80) for deforming the surface portion along a spherical surface segment, and a pencil tool (90) for manually drawing a line to which the surface portion is redefined.

    Abstract translation: 扫描器（18）获取被摄体的图像。 从器官模型数据库（50）中选择器官的3D模型（52）并且落在实际器官的图像上。 最佳拟合装置（62）在全局范围内缩放，平移和/或旋转模型（52）以最佳地适合由图像表示的实际器官。 用户使用鼠标（38）使用一组手动工具（68）来分割和操纵模型（52）1：o匹配图像数据。 所述工具集（68）包括：用于使模型的表面部分沿着高斯曲线变形的高斯工具（72），用于使表面部分沿着球形表面段变形的球形推动工具（80）和铅笔工具 （90），用于手动绘制重新定义表面部分的线。

    DATA REPRESENTATION FOR RTP
    4.
    发明申请
    DATA REPRESENTATION FOR RTP 有权
    RTP的数据表示

    公开(公告)号：US20090074264A1

    公开(公告)日：2009-03-19

    申请号：US11719781

    申请日：2005-11-04

    Applicant: Vladimir Pekar ,  Michael Kaus ,  Ingwer C. Carlsen ,  Todd R. McNutt ,  R. Keith Tipton

    Inventor： Vladimir Pekar ,  Michael Kaus ,  Ingwer C. Carlsen ,  Todd R. McNutt ,  R. Keith Tipton

    IPC: G06K9/00

    CPC classification number: A61B6/032 ,  A61B6/4417 ,  A61B6/5235 ,  A61B8/13 ,  A61B8/4416 ,  A61N5/103 ,  A61N5/1039 ,  G01T1/1611 ,  G06T7/33 ,  G06T2207/30004

    Abstract: An imaging system (10) includes imaging modalities such as a PET imaging system (12) and a CT scanner (14). The CT scanner (14) is used to produce a first image (62) which is used for primary contouring. The PET system (12) is used to provide a second image (56), which provides complementary information about the same or overlapping anatomical region. After first and second images (62, 56) are registered with one another the first and second images (62, 56) are concurrently segmented to outline a keyhole (76). The keyhole portion of the second image (56) is inserted into the keyhole (76) of the first image (62). The user can observe the composite image and deform a boundary (78) of the keyhole (76) by a mouse (52) to better focus on the region of interest within previously defined keyhole.

    Abstract translation: 成像系统（10）包括诸如PET成像系统（12）和CT扫描仪（14）之类的成像模式。 CT扫描器（14）用于产生用于初级轮廓的第一图像（62）。 PET系统（12）用于提供第二图像（56），其提供关于相同或重叠解剖区域的补充信息。 在第一和第二图像（62,56）之间彼此对准之后，第一和第二图像（62,56）被同时分割以勾勒一个键孔（76）。 第二图像（56）的锁孔部分插入第一图像（62）的键孔（76）中。 用户可以观察合成图像并且通过鼠标（52）使键孔（76）的边界（78）变形以更好地聚焦在先前定义的键孔内的感兴趣区域上。

    Radiotherapeutic treatment plan adaptation
    6.
    发明授权
    Radiotherapeutic treatment plan adaptation 有权
    放射治疗计划适应

    公开(公告)号：US08306185B2

    公开(公告)日：2012-11-06

    申请号：US11573564

    申请日：2005-07-28

    Applicant: Matthieu Bal ,  Lothar Spies ,  Todd R. McNutt

    Inventor： Matthieu Bal ,  Lothar Spies ,  Todd R. McNutt

    IPC: A61N5/10

    CPC classification number: A61N5/103 ,  A61N5/1031 ,  A61N2005/1061 ,  G06F19/00 ,  G06F19/3481

    Abstract: In a radiation therapy method, one or more planning images are acquired (102) of a subject. Features of at least malignant tissue are contoured in the one or more planning images to produce one or more initial feature contours. One or more treatment images of the subject are acquired (114). The one or more initial feature contours are updated (122) based on the one or more treatment images. Radiation treatment parameters are optimized (126) based upon the updated one or more feature contours. Radiation treatment of the subject is performed (130) using the optimized parameters.

    Abstract translation: 在放射治疗方法中，获取对象的一个​​或多个规划图像（102）。 至少恶性组织的特征在一个或多个规划图像中具有轮廓，以产生一个或多个初始特征轮廓。 获取对象的一个​​或多个处理图像（114）。 一个或多个初始特征轮廓基于一个或多个治疗图像被更新（122）。 基于更新的一个或多个特征轮廓对辐射处理参数进行优化（126）。 使用优化的参数进行受试者的放射治疗（130）。

    Data representation for rtp
    7.
    发明授权
    Data representation for rtp 有权
    rtp的数据表示

    公开(公告)号：US08260013B2

    公开(公告)日：2012-09-04

    申请号：US11719781

    申请日：2005-11-04

    Applicant: Vladimir Pekar ,  Michael Kaus ,  Ingwer C. Carlsen ,  Todd R. McNutt ,  R. Keith Tipton

    Inventor： Vladimir Pekar ,  Michael Kaus ,  Ingwer C. Carlsen ,  Todd R. McNutt ,  R. Keith Tipton

    IPC: G06K9/00

    CPC classification number: A61B6/032 ,  A61B6/4417 ,  A61B6/5235 ,  A61B8/13 ,  A61B8/4416 ,  A61N5/103 ,  A61N5/1039 ,  G01T1/1611 ,  G06T7/33 ,  G06T2207/30004

    Abstract: An imaging system (10) includes imaging modalities such as a PET imaging system (12) and a CT scanner (14). The CT scanner (14) is used to produce a first image (62) which is used for primary contouring. The PET system (12) is used to provide a second image (56), which provides complementary information about the same or overlapping anatomical region. After first and second images (62, 56) are registered with one another the first and second images (62, 56) are concurrently segmented to outline a keyhole (76). The keyhole portion of the second image (56) is inserted into the keyhole (76) of the first image (62). The user can observe the composite image and deform a boundary (78) of the keyhole (76) by a mouse (52) to better focus on the region of interest within previously defined keyhole.

    Abstract translation: 成像系统（10）包括诸如PET成像系统（12）和CT扫描仪（14）之类的成像模式。 CT扫描器（14）用于产生用于初级轮廓的第一图像（62）。 PET系统（12）用于提供第二图像（56），其提供关于相同或重叠解剖区域的补充信息。 在第一和第二图像（62,56）之间彼此对准之后，第一和第二图像（62,56）被同时分割以勾勒一个键孔（76）。 第二图像（56）的锁孔部分插入第一图像（62）的键孔（76）中。 用户可以观察合成图像并且通过鼠标（52）使键孔（76）的边界（78）变形以更好地聚焦在先前定义的键孔内的感兴趣区域上。

    Inverse planning for intensity-modulated radiotherapy
    8.
    发明授权
    Inverse planning for intensity-modulated radiotherapy 有权
    强度调制放疗的反向规划

    公开(公告)号：US06735277B2

    公开(公告)日：2004-05-11

    申请号：US10154135

    申请日：2002-05-23

    Applicant: Todd R. McNutt ,  R. Keith Tipton ,  R. Terry Ward ,  Scott L. Johnson

    Inventor： Todd R. McNutt ,  R. Keith Tipton ,  R. Terry Ward ,  Scott L. Johnson

    IPC: A61N510

    CPC classification number: A61N5/1031

    Abstract: A radiation treatment apparatus (10) includes a diagnostic imaging scanner (12) that acquires a diagnostic image of a subject. A contouring processor (54) computes a radiation treatment objective based thereon. A radiation delivery apparatus (60) delivers radiation to the subject. An inverse planning processor (80) computes radiation beamlet parameters conforming with the radiation treatment objective by: grouping the beamlet parameters; assigning a weight to each group (82, 84, 86); optimizing a first group (82) to produce an intermediate dosage objective corresponding to the treatment objective weighted by a weight of the first group (82); and optimizing successive groups (84) to produce with the previously optimized groups (82) an increasing intermediate dosage objective corresponding to the treatment objective weighted by the combined weights of the previous and current groups (82, 84). A conversion processor (90) converts the optimized beamlet parameters into configuration parameters of the radiation delivery apparatus (60).

    Abstract translation: 一种放射治疗装置（10）包括获取对象的诊断图像的诊断成像扫描仪（12）。 轮廓处理器（54）基于此计算辐射处理目标。 辐射输送装置（60）将辐射传送到对象。 逆规划处理器（80）通过以下方式计算符合辐射处理目标的辐射小波参数：分组子束参数; 为每个组分配权重（82,84,86）; 优化第一组（82）以产生对应于由第一组（82）的权重加权的治疗目标的中间剂量目标; 以及优化连续组（84）以与先前优化的组（82）一起生成对应于由先前组和当前组（82,84）的组合权重加权的治疗目标的增加的中间剂量目标。 转换处理器（90）将优化的子束参数转换成辐射递送装置（60）的配置参数。

    REAL-TIME DOSE COMPUTATION FOR RADIATION THERAPY USING GRAPHICS PROCESSING UNIT ACCELERATION OF THE CONVOLUTION/SUPERPOSITION DOSE COMPUTATION METHOD
    10.
    发明申请
    REAL-TIME DOSE COMPUTATION FOR RADIATION THERAPY USING GRAPHICS PROCESSING UNIT ACCELERATION OF THE CONVOLUTION/SUPERPOSITION DOSE COMPUTATION METHOD 有权
    使用图形处理单元进行放射治疗的实时剂量计算加速转染/超级剂量计算方法

    公开(公告)号：US20110051893A1

    公开(公告)日：2011-03-03

    申请号：US12934513

    申请日：2009-05-08

    Applicant: Todd R. McNutt ,  Robert Allan Jacques

    Inventor： Todd R. McNutt ,  Robert Allan Jacques

    IPC: A61N5/10 ,  A61B5/05

    CPC classification number: A61N5/1031 ,  A61N2005/1034

    Abstract: A system for radiation therapy including a radiation planning system, wherein the radiation planning system comprises a parallel processor adapted to receive input information concerning a body having an intended radiation treatment region and to output information for providing radiation treatment to the intended radiation treatment region of the body, wherein the parallel processor is adapted to perform a plurality of reverse ray tracing calculations based on the input information concerning the body in determining the output information for providing radiation treatment, each of the plurality of reverse ray tracing calculations comprising: calculating a first physical property corresponding to a first sub-region of the intended radiation treatment region of the body that is intersected by a ray traced between a source position and the intended radiation treatment region; and calculating, subsequent to the first-mentioned calculating, a second physical property corresponding to a second sub-region of the intended radiation treatment region that is intersected by the ray at a location closer to the source position than is the first sub-region.

    Abstract translation: 一种用于包括辐射计划系统的放射治疗系统，其中所述辐射计划系统包括并行处理器，其适于接收关于具有预期辐射治疗区域的身体的输入信息，并输出用于向所述辐射治疗区域的预期辐射治疗区域提供辐射治疗的信息 其中所述并行处理器适于在确定用于提供放射治疗的输出信息时，基于关于身体的输入信息执行多个反射光线跟踪计算，所述多个反射光线跟踪计算中的每一个包括：计算第一物理 对应于由源位置和预期辐射处理区域之间的轨迹相交的身体的预期辐射治疗区域的第一子区域; 以及在所述第一次计算之后，计算与所述预期辐射处理区域的第二子区域相对应的第二物理特性，所述第二子区域在与所述第一子区域相比更靠近所述源位置的位置与所述射线相交。

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