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1.Methods of making FGF-21 mutants comprising non-naturally encoded phenylalanine derivatives 有权
Title translation: 制备包含非天然编码的苯丙氨酸衍生物的FGF-21突变体的方法公开(公告)号:US08383365B2
公开(公告)日:2013-02-26
申请号:US13051953
申请日:2011-03-18
Applicant: Thomas P. Cujec , Roberto Mariani , Anna-Maria A. Hays Putnam , William M. Keefe , Nick Knudsen , Lillian Skidmore (Nee Ho) , Jason Pinkstaff , Vadim Kraynov
Inventor: Thomas P. Cujec , Roberto Mariani , Anna-Maria A. Hays Putnam , William M. Keefe , Nick Knudsen , Lillian Skidmore (Nee Ho) , Jason Pinkstaff , Vadim Kraynov
CPC classification number: C07K14/50 , A61K38/00 , A61K38/1825 , A61K45/06 , A61K47/60 , C12N15/70 , Y02A50/473
Abstract: Modified FGF-21 polypeptides and uses thereof are provided.
Abstract translation: 提供了修饰的FGF-21多肽及其用途。
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2.HIV trans-activator Tat binding to CDK7 and activation of CTD phosphorylation 失效
Title translation: HIV反式激活剂Tat与CDK7结合并激活CTD磷酸化公开(公告)号:US5994055A
公开(公告)日:1999-11-30
申请号:US943495
申请日:1997-10-03
Applicant: Thomas P. Cujec , B. Matija Peterlin
Inventor: Thomas P. Cujec , B. Matija Peterlin
CPC classification number: C07K14/005 , A61K38/00 , C12N2740/16322
Abstract: The present invention relates to methods of inhibiting Tat trans-activation in a cell and methods of assaying for inhibitors of Tat trans-activation.
Abstract translation: 本发明涉及抑制细胞中Tat反式激活的方法以及测定Tat反式激活抑制剂的方法。
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公开(公告)号:US09175083B2
公开(公告)日:2015-11-03
申请号:US11873372
申请日:2007-10-16
Applicant: Ho Sung Cho , Thomas O. Daniel , Troy E. Wilson , Thomas P. Cujec , Feng Tian , Anna-Maria A. Hays , Bruce E. Kimmel , Lillian Ho
Inventor: Ho Sung Cho , Thomas O. Daniel , Troy E. Wilson , Thomas P. Cujec , Feng Tian , Anna-Maria A. Hays , Bruce E. Kimmel , Lillian Ho
IPC: C07K16/28 , C07K14/195 , C07K14/47 , C07K16/32
CPC classification number: C07K16/2863 , C07K14/195 , C07K14/47 , C07K16/32 , C07K2317/34 , C07K2317/41 , C07K2317/55 , C07K2317/622
Abstract: Novel antigen-binding polypeptides (ABP) and uses thereof are provided.
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公开(公告)号:US08012931B2
公开(公告)日:2011-09-06
申请号:US12051830
申请日:2008-03-19
Applicant: Thomas P. Cujec , Roberto Mariani , Anna-Maria A. Hays Putnam , William M. Keefe , Nick Knudsen , Lillian Ho , Jason Pinkstaff , Vadim Kraynov
Inventor: Thomas P. Cujec , Roberto Mariani , Anna-Maria A. Hays Putnam , William M. Keefe , Nick Knudsen , Lillian Ho , Jason Pinkstaff , Vadim Kraynov
CPC classification number: C07K14/50 , A61K38/00 , A61K38/1825 , A61K45/06 , A61K47/60 , C12N15/70 , Y02A50/473
Abstract: Modified FGF-21 polypeptides and uses thereof are provided.
Abstract translation: 提供了修饰的FGF-21多肽及其用途。
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公开(公告)号:US20110172401A1
公开(公告)日:2011-07-14
申请号:US13051953
申请日:2011-03-18
Applicant: Thomas P. CUJEC , Roberto MARIANI , Anna-Maria A. HAYS PUTNAM , William M. KEEFE , Nick KNUDSEN , Lillian Ho , Jason PINKSTAFF , Vadim KRAYNOV
Inventor: Thomas P. CUJEC , Roberto MARIANI , Anna-Maria A. HAYS PUTNAM , William M. KEEFE , Nick KNUDSEN , Lillian Ho , Jason PINKSTAFF , Vadim KRAYNOV
IPC: C07K1/107
CPC classification number: C07K14/50 , A61K38/00 , A61K38/1825 , A61K45/06 , A61K47/60 , C12N15/70 , Y02A50/473
Abstract: Modified FGF-21 polypeptides and uses thereof are provided.
Abstract translation: 提供了修饰的FGF-21多肽及其用途。
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公开(公告)号:US07632924B2
公开(公告)日:2009-12-15
申请号:US11155909
申请日:2005-06-17
Applicant: Ho Sung Cho , Thomas O. Daniel , Troy E. Wilson , Thomas P. Cujec , Feng Tian , Anna-Maria Hays , Bruce E. Kimmel , Lillian Ho
Inventor: Ho Sung Cho , Thomas O. Daniel , Troy E. Wilson , Thomas P. Cujec , Feng Tian , Anna-Maria Hays , Bruce E. Kimmel , Lillian Ho
IPC: C12P21/08
CPC classification number: C07K16/2863 , C07K14/195 , C07K14/47 , C07K16/32 , C07K2317/34 , C07K2317/41 , C07K2317/55 , C07K2317/622
Abstract: Novel antigen-binding polypeptides (ABP) and uses thereof are provided.
Abstract translation: 提供了新的抗原结合多肽(ABP)及其用途。
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公开(公告)号:US20080255045A1
公开(公告)日:2008-10-16
申请号:US12051830
申请日:2008-03-19
Applicant: Thomas P. CUJEC , Roberto MARIANI , Anna-Maria A. HAYS PUTNAM , William M. KEEFE , Nick KNUDSEN , Lillian HO , Jason PINKSTAFF , Vadim KRAYNOV
Inventor: Thomas P. CUJEC , Roberto MARIANI , Anna-Maria A. HAYS PUTNAM , William M. KEEFE , Nick KNUDSEN , Lillian HO , Jason PINKSTAFF , Vadim KRAYNOV
CPC classification number: C07K14/50 , A61K38/00 , A61K38/1825 , A61K45/06 , A61K47/60 , C12N15/70 , Y02A50/473
Abstract: Modified FGF-21 polypeptides and uses thereof are provided.
Abstract translation: 提供了修饰的FGF-21多肽及其用途。
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8.HIV trans-activator TAT binding to CDK7 and activation of CTD phosphorylation 失效
Title translation: HIV反式激活剂TAT与CDK7结合并激活CTD磷酸化公开(公告)号:US6159684A
公开(公告)日:2000-12-12
申请号:US420081
申请日:1999-10-18
Applicant: Thomas P. Cujec , B. Matija Peterlin
Inventor: Thomas P. Cujec , B. Matija Peterlin
CPC classification number: C07K14/005 , A61K38/00 , C12N2740/16322
Abstract: The present invention relates to methods of inhibiting Tat trans-activation in a cell and methods of assaying for inhibitors of Tat trans-activation.
Abstract translation: 本发明涉及抑制细胞中Tat反式激活的方法以及测定Tat反式激活抑制剂的方法。
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