公开(公告)号：US20030148509A1

公开(公告)日：2003-08-07

申请号：US10272394

申请日：2002-10-15

Applicant: The Govt. of the USA, as represented by the secretary, Dept. of Health and Human Services

Inventor： Margaret E. Callahan ,  Thomas M. Folks ,  Paul Sandstrom ,  Shambavi Subbarao ,  Jennifer Brown ,  Walid Heneine ,  William M. Switzer

IPC: C12Q001/68 ,  C12P021/06 ,  C12N007/00 ,  C12N007/01 ,  C12N015/00 ,  C12N015/09 ,  C12N015/63 ,  C12N015/70 ,  C12N015/74

CPC classification number: C07K14/005 ,  A61K48/00 ,  C12N7/00 ,  C12N15/86 ,  C12N2740/17021 ,  C12N2740/17022 ,  C12N2740/17043

Abstract: The present invention comprises spumavirus isolated from humans. More specifically, the spumavirus of the present invention was isolated from humans who had exposure to nonhuman primates. Importantly, the spumavirus of the present invention or antibodies to the spumavirus can be used to detect the presence of spumavirus or antibodies in body fluids, for pathogenicity studies of related viruses, and as a vector for gene therapies. The spumavirus of the invention can also be used for treatment of conditions in humans due to the presence of rapidly dividing cells and for recombinant live virus vaccination.