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公开(公告)号：US08445581B2
公开(公告)日：2013-05-21
申请号：US12309794
申请日：2007-08-02
申请人： Pathiraja Arachchillage Gunatillake , Roshan Tyrrel Anton Mayadunne , Raju Adhikari , Heng Chy Taing , Tam Phuong Thi Le , Jerome Anthony Werkmeister , John Alan Maurice Ramshaw , Jacinta Frances White , Tracy Ann Tebb
发明人： Pathiraja Arachchillage Gunatillake , Roshan Tyrrel Anton Mayadunne , Raju Adhikari , Heng Chy Taing , Tam Phuong Thi Le , Jerome Anthony Werkmeister , John Alan Maurice Ramshaw , Jacinta Frances White , Tracy Ann Tebb
IPC分类号： C08F290/02 , C08F299/00 , C08G63/08 , C08L33/04
CPC分类号： C08G18/4277 , A61L27/16 , C08F290/00 , C08F290/02 , C08F299/00 , C08G18/10 , C08G18/4833 , C08G18/771 , C08G18/8116 , C08G63/08 , C08G63/664 , C08G2230/00 , C08L53/00 , C08L53/005 , C08L53/02 , C08L2666/02
摘要： The present invention provides a biocompatible prepolymer comprising hydrophilic and hydrophobic segments, wherein the hydrophobic segments have at least one ethylenically unsaturated functional group and at least 5% of the segments have two or more ethylenically unsaturated functional groups and water. The invention further provides a biocompatible prepolymer composition comprising hydrophilic and hydrophobic prepolymers, wherein at least one of the hydrophobic prepolymers has at least one ethylenically unsaturated functional group and at least 5% of the prepolymers have two or more ethylenically unsaturated functional groups and water. The invention further provides use of the prepolymer or prepolymer compositions of the invention in biomedical applications such as tissue engineering, as bone substitutes or scaffolds, and in wound treatment.
摘要翻译： 本发明提供了包含亲水和疏水链段的生物相容性预聚物，其中疏水链段具有至少一个烯键式不饱和官能团，并且至少5％的链段具有两个或多个烯键式不饱和官能团和水。 本发明还提供了包含亲水和疏水预聚物的生物相容性预聚物组合物，其中至少一种疏水性预聚物具有至少一个烯键式不饱和官能团，并且至少5％的预聚物具有两个或更多个烯属不饱和官能团和水。 本发明进一步提供本发明的预聚物或预聚物组合物在生物医学应用如组织工程，骨替代物或支架中的用途，以及在伤口治疗中的用途。
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公开(公告)号：US20090324675A1
公开(公告)日：2009-12-31
申请号：US12309794
申请日：2007-08-02
申请人： Pathiraja Arachchillage Gunatillake , Roshan Tyrrel Anton Mayadunne , Raju Adhikari , Heng Chy Taing , Tam Phuong Thi Le , Jerome Anthony Werkmeister , John Alan Maurice Ramshaw , Jacinta Frances White , Tracy Ann Tebb
发明人： Pathiraja Arachchillage Gunatillake , Roshan Tyrrel Anton Mayadunne , Raju Adhikari , Heng Chy Taing , Tam Phuong Thi Le , Jerome Anthony Werkmeister , John Alan Maurice Ramshaw , Jacinta Frances White , Tracy Ann Tebb
CPC分类号： C08G18/4277 , A61L27/16 , C08F290/00 , C08F290/02 , C08F299/00 , C08G18/10 , C08G18/4833 , C08G18/771 , C08G18/8116 , C08G63/08 , C08G63/664 , C08G2230/00 , C08L53/00 , C08L53/005 , C08L53/02 , C08L2666/02
摘要： The present invention provides a biocompatible prepolymer comprising hydrophilic and hydrophobic segments, wherein the hydrophobic segments have at least one ethylenically unsaturated functional group and at least 5% of the segments have two or more ethylenically unsaturated functional groups and water. The invention further provides a biocompatible prepolymer composition comprising hydrophilic and hydrophobic prepolymers, wherein at least one of the hydrophobic prepolymers has at least one ethylenically unsaturated functional group and at least 5% of the prepolymers have two or more ethylenically unsaturated functional groups and water. The invention further provides use of the prepolymer or prepolymer compositions of the invention in biomedical applications such as tissue engineering, as bone substitutes or scaffolds, and in wound treatment.
摘要翻译： 本发明提供了包含亲水和疏水链段的生物相容性预聚物，其中疏水链段具有至少一个烯键式不饱和官能团，并且至少5％的链段具有两个或多个烯键式不饱和官能团和水。 本发明还提供了包含亲水和疏水预聚物的生物相容性预聚物组合物，其中至少一种疏水性预聚物具有至少一个烯键式不饱和官能团，并且至少5％的预聚物具有两个或更多个烯属不饱和官能团和水。 本发明进一步提供本发明的预聚物或预聚物组合物在生物医学应用如组织工程，骨替代物或支架中的用途，以及在伤口治疗中的用途。
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