摘要:
A submerged-type hollow fiber membrane module and a method for manufacturing the same are disclosed, which is capable of realizing a great sealing strength between a module case and a bundle of hollow fiber membranes without an additional centrifugal molding apparatus. The method includes forming a bundle of hollow fiber membranes held together and fixed by a first potting material, wherein one end of each of the hollow fiber membranes is open; putting the bundle of hollow fiber membranes in a module case and fixing the bundle of hollow fiber membranes in the module case by forming a second potting material on the first potting material.
摘要:
The present invention relates to novel derivatives of oxazolidinone, a method thereof and pharmaceutical compositions comprising the derivatives for use in an antibiotic. The oxazolidinone derivatives of the present invention show inhibitory activity against a broad spectrum of bacteria and lower toxicity. The prodrugs, prepared by reacting the compound having hydroxyl group with amino acid or phosphate, have an excellent efficiency on solubility thereof against water. Further, the derivatives of the present invention may exert potent antibacterial activity versus various human and animal pathogens, including Gram-positive bacteria such as Staphylococi, Enterococci and Streptococi, anaerobic microorganisms such as Bacteroides and Clostridia, and acid-resistant microorganisms such as Mycobacterium tuberculosis and Mycobacterium avium. Accordingly, the compositions comprising the oxazolidinone are used in an antibiotic.
摘要:
The present invention provides a novel benzamide derivative or a pharmaceutically acceptable salt thereof, a method for preparing the same, and a 5-HT4 receptor agonist containing the same as an active ingredient. Benzamide derivatives of the present invention have a superior affinity for 5-HT4 receptors, a capability to reduce a gastric emptying time and a low toxicity, and consequently are therapeutically effective for the treatment of a variety of diseases associated with 5-HT4 receptors.
摘要:
The present invention relates to novel derivatives of oxazolidinone, a method thereof and pharmaceutical compositions comprising the derivatives for use in an antibiotic. The oxazolidinone derivatives of the present invention show inhibitory activity against a broad spectrum of bacteria and lower toxicity. The prodrugs, prepared by reacting the compound having hydroxyl group with amino acid or phosphate, have an excellent efficiency on solubility thereof against water. Further, the derivatives of the present invention may exert potent antibacterial activity versus various human and animal pathogens, including Gram-positive bacteria such as, Staphylococci, Enterococci and Streptococci anaerobic microorganisms such as Bacteroides and Clostridia, and acid-resistant microorganisms such as Mycobacterium tuberculosis and Mycobacterium avium. Accordingly, the compositions comprising the oxazolidinone are used in an antibiotic.
摘要:
The present invention provides a novel benzamide derivative or a pharmaceutically acceptable salt thereof, a method for preparing the same, and a 5-HT4 receptor agonist containing the same as an active ingredient. Benzamide derivatives of the present invention have a superior affinity for 5-HT4 receptors, a capability to reduce a gastric emptying time and a low toxicity, and consequently are therapeutically effective for the treatment of a variety of diseases associated with 5-HT4 receptors.
摘要:
A tubular braid and a composite hollow fiber membrane using the same are disclosed. The tubular braid is made by braiding yarns, the yarn made by combining thin filament and thick filament, wherein the thin filament is comprised of a plurality of monofilament having a fineness of 0.01 to 0.4 denier, and the thick filament is comprised of at least one monofilament having a fineness of 3 to 50 denier. Also, the composite hollow fiber membrane using the tubular braid of the present invention can realize excellent water permeability, high mechanical strength, good filtration reliability, great peeling strength, low dope permeation, and high stiffness.
摘要:
A braid-reinforced hollow fiber membrane which includes a reinforcing material of a tubular braid and a polymer resinous thin film coated on the surface of the reinforcing material. The polymer resinous thin film has a skin layer with micro pores having a diameter in the range from 0.01 to 1 μm and an inner layer of a sponge structure with micro pores having a diameter less than 10 μm.The hollow fiber membrane exhibits excellent mechanical strength, reliable filtration and simultaneously, good water permeability.
摘要:
The present invention provides a novel benzamide derivative represented by formula 1 and an isomer, a pharmaceutically acceptable salt or hydrate thereof, and a composition for activating a 5-HT 4 receptor comprising the same, as an active ingredient. Benzamide derivatives of the present invention has superior affinity for 5-HT 4 receptors, capability to reduce the gastric evacuation time, capability to alleviate ventricular tachycardia, ventricular fibrillation, torsades de pointes and QT prolongation, and low toxicity. Therefore, benzamide derivatives of the present invention are therapeutically effective for digestive system diseases.
摘要:
A submerged-type hollow fiber membrane module and a method for manufacturing the same are disclosed, which is capable of realizing a great sealing strength between a module case and a bundle of hollow fiber membranes without an additional centrifugal molding apparatus. The method includes forming a bundle of hollow fiber membranes held together and fixed by a first potting material, wherein one end of each of the hollow fiber membranes is open; putting the bundle of hollow fiber membranes in a module case and fixing the bundle of hollow fiber membranes in the module case by forming a second potting material on the first potting material.
摘要:
The present invention relates to novel derivatives of oxazolidinone, a method thereof and pharmaceutical compositions comprising the derivatives for use in an antibiotic. The oxazolidinone derivatives of the present invention show inhibitory activity against a broad spectrum of bacteria and lower toxicity. The prodrugs, prepared by reacting the compound having hydroxyl group with amino acid or phosphate, have an excellent efficiency on solubility thereof against water. Further, the derivatives of the present invention may exert potent antibacterial activity versus various human and animal pathogens, including Gram-positive bacteria such as Staphylococi, Enterococci and Streptococi, anaerobic microorganisms such as Bacteroides and Clostridia, and acid-resistant microorganisms such as Mycobacterium tuberculosis and Mycobacterium avium. Accordingly, the compositions comprising the oxazolidinone are used in an antibiotic.