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    Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase
    1.
    发明申请
    Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase 审中-公开
    核苷衍生物作为rna依赖性rna病毒聚合酶的抑制剂

    公开(公告)号：US20070004669A1

    公开(公告)日：2007-01-04

    申请号：US10517295

    申请日：2003-06-17

    申请人： Steven Carroll ,  David Olsen ,  Philippe Durette ,  Balkrishen Bhat ,  Prasad Dande ,  Anne Eldrup

    发明人： Steven Carroll ,  David Olsen ,  Philippe Durette ,  Balkrishen Bhat ,  Prasad Dande ,  Anne Eldrup

    IPC分类号： A61K31/7076 ,  A61K31/7072 ,  C07H19/04 ,  C07H19/167 ,  C07H19/12

    CPC分类号： C07H19/04 ,  C07H19/06 ,  C07H19/10 ,  C07H19/12 ,  C07H19/16 ,  C07H19/167 ,  C07H19/20

    摘要： The present invention provides nucleoside compounds and certain derivatives thereof which are inhibitors of RNA-dependent RNA viral polymerase. These compounds are inhibitors of RNA-dependent RNA viral replication and are useful for the treatment of RNA-dependent RNA viral infection. They are particularly useful as inhibitors of hepatitis C virus (HCV) NS5B polymerase, as inhibitors of HCV replication, and/or for the treatment of hepatitis C infection. The invention also describes pharmaceutical compositions containing such nucleoside compounds alone or in combination with other agents active against RNA-dependent RNA viral infection, in particular HCV infection. Also disclosed are methods of inhibiting RNA-dependent RNA polymerase, inhibiting RNA-dependent RNA viral replication, and/or treating RNA-dependent RNA viral infection with the nucleoside compounds of the present invention.

    摘要翻译： 本发明提供作为RNA依赖性RNA病毒聚合酶抑制剂的核苷化合物及其某些衍生物。 这些化合物是RNA依赖性RNA病毒复制的抑制剂，可用于治疗RNA依赖性RNA病毒感染。 它们特别可用作丙型肝炎病毒（HCV）NS5B聚合酶的抑制剂，作为HCV复制的抑制剂和/或用于治疗丙型肝炎感染。 本发明还描述了单独或与其它对RNA依赖性RNA病毒感染（特别是HCV感染）有活性的试剂组合的药物组合物。 还公开了本发明的核苷化合物抑制RNA依赖性RNA聚合酶，抑制RNA依赖性RNA病毒复制和/或治疗RNA依赖性RNA病毒感染的方法。

    Method and apparatus for performance analysis on a software program
    5.
    发明申请
    Method and apparatus for performance analysis on a software program 有权
    用于软件程序性能分析的方法和装置

    公开(公告)号：US20060248401A1

    公开(公告)日：2006-11-02

    申请号：US11107464

    申请日：2005-04-15

    申请人： Steven Carroll ,  Eric Lee ,  Simon Meacham

    发明人： Steven Carroll ,  Eric Lee ,  Simon Meacham

    IPC分类号： G06F11/00

    CPC分类号： G06F11/3664 ,  G06F11/323 ,  G06F11/3423 ,  G06F11/3466 ,  G06F2201/86 ,  G06F2201/865

    摘要： A system for displaying performance test information for software. The system includes a graphical user interface that displays information in a format to allow ready identification of performance problems and their causes. The interface includes a timeline view depicting activity levels during the execution of a program under test. Events during a sub-range of times during the program execution may be displayed with information revealing interactions of threads making up the program. Additional information may be displayed in a further display fields, including textual information. Much of the displayed information is represented graphically, allowing a performance engineer to quickly identify areas of the program to investigate further.

    摘要翻译： 用于显示软件性能测试信息的系统。 该系统包括以格式显示信息以允许准确识别性能问题及其原因的图形用户界面。 该界面包括描述在执行被测程序期间的活动级别的时间线视图。 在程序执行期间的子范围内的事件可以显示出显示构成程序的线程的交互的信息。 附加信息可以显示在另外的显示字段中，包括文本信息。 所显示的大部分信息都以图形方式表示，从而让演奏工程师能够快速识别程序的进一步调查区域。

    Methods and apparatus for handling code coverage data
    6.
    发明申请
    Methods and apparatus for handling code coverage data 审中-公开
    处理代码覆盖率数据的方法和装置

    公开(公告)号：US20060236156A1

    公开(公告)日：2006-10-19

    申请号：US11106869

    申请日：2005-04-15

    申请人： John Cunningham ,  Steven Carroll

    发明人： John Cunningham ,  Steven Carroll

    IPC分类号： G06F11/00

    CPC分类号： G06F11/3676

    摘要： In one aspect, a method and apparatus for formatting code coverage data generated by performing one or more code coverage tests on a program module derived from computer code is provided, including organizing the code coverage data in a hierarchy having a plurality of tables, each of the plurality of tables configured to store information at one of successive levels of refinement, and storing, in each of the plurality of tables, code coverage information indicative of code coverage at a respective one of the successive levels of refinement. In another aspect, a data structure for storing code coverage data is provided, the data structure comprising a plurality of tables organized in a hierarchy having a plurality of levels, each of the plurality of levels corresponding to a respective construct in the programming paradigm used to structure the code, wherein each of the plurality of tables comprises a first location configured to store code coverage information at the level in the hierarchy at which the table is located.

    摘要翻译： 一方面，提供了一种通过对从计算机代码导出的程序模块执行一个或多个代码覆盖测试而产生的代码覆盖率数据格式化的方法和装置，包括在具有多个表的层次中组织代码覆盖数据， 所述多个表被配置为在渐进级中的一个级别存储信息，并且在所述多个表中的每一个中存储指示所述连续级别的细化中的相应级别的代码覆盖率的代码覆盖率信息。 在另一方面，提供了一种用于存储代码覆盖数据的数据结构，所述数据结构包括组织在具有多个级别的层级中的多个表格，所述多个级别中的每一个级别对应于所述编程范例中的相应结构， 结构化代码，其中所述多个表中的每一个包括被配置为存储所述表所在的层级中的级别的代码覆盖率信息的第一位置。

    Determining an actual amount of time a processor consumes in executing a portion of code
    7.
    发明申请
    Determining an actual amount of time a processor consumes in executing a portion of code 有权
    确定处理器在执行代码部分时消耗的实际时间

    公开(公告)号：US20060212867A1

    公开(公告)日：2006-09-21

    申请号：US11082398

    申请日：2005-03-17

    申请人： Mahlon Fields ,  Richard Wurdack ,  Steven Carroll ,  Barry Nolte

    发明人： Mahlon Fields ,  Richard Wurdack ,  Steven Carroll ,  Barry Nolte

    IPC分类号： G06F9/46

    CPC分类号： G06F11/3423

    摘要： Systems and methods are provided that determine the actual amount of time a processor consumes in executing a code portion. The actual execution time of a code portion may be accurately determined by taking into consideration context switches and/or overhead time corresponding to the code portion. Determining the actual execution time of a code portion may include recording context switches and time values that occur during the execution of the code portion. This information along with overhead measurements may be used to generate the actual execution time of a code portion, as will be described in more detail below. For example, the switched-out intervals resulting from the context switches and the overhead time associated with the time measurements may be subtracted from the elapsed time to produce the actual execution time of a code portion.

    摘要翻译： 提供了确定处理器在执行代码部分时消耗的实际时间量的系统和方法。 可以通过考虑与代码部分相对应的上下文切换和/或开销时间来精确地确定代码部分的实际执行时间。 确定代码部分的实际执行时间可以包括在执行代码部分期间记录上下文切换和时间值。 该信息以及开销测量可以用于生成代码部分的实际执行时间，如将在下面更详细描述的。 例如，从上下文切换产生的切换间隔和与时间测量相关联的开销时间可以从经过的时间中减去以产生代码部分的实际执行时间。

    MOBILE PLATFORM FOR EVENT REGISTRATION
    8.
    发明申请
    MOBILE PLATFORM FOR EVENT REGISTRATION 有权
    活动注册的移动平台

    公开(公告)号：US20130124398A1

    公开(公告)日：2013-05-16

    申请号：US13297123

    申请日：2011-11-15

    申请人： STEVEN CARROLL ,  PETER DE TAGYOS ,  JOSH SCHLESSER

    发明人： STEVEN CARROLL ,  PETER DE TAGYOS ,  JOSH SCHLESSER

    IPC分类号： G06K5/00 ,  G06Q40/00

    CPC分类号： G06Q99/00 ,  G06Q10/00 ,  G06Q10/10 ,  G06Q20/00 ,  G06Q20/40 ,  G06Q40/00 ,  G06Q90/00

    摘要： Method and systems of registering participants for an event at an event site are disclosed. Identification data specific to a participant encoded on a first token object is read with a mobile computing device. A query is generated from the mobile computing device to a remote event registration system for prior registration data based upon at least a subset of the received identification data. The prior registration data is received on the mobile computing device. A first subset of the prior registration data is transmitted to a local event registration system, and a payment success indicator is received upon successful payment processing. Registrant identification data is generated by the local event registration system in response to recording the first subset of the prior registration data and the payment success indicator.

    摘要翻译： 公开了在事件现场注册事件的参与者的方法和系统。 使用移动计算设备读取特定于在第一令牌对象上编码的参与者的识别数据。 基于所接收的标识数据的至少一个子集，从移动计算设备向远程事件注册系统生成用于先前注册数据的查询。 在移动计算设备上接收先前的注册数据。 先前注册数据的第一个子集被发送到本地事件注册系统，并且在成功的支付处理之后接收到支付成功指示符。 响应于记录先前注册数据的第一子集和支付成功指示符，由本地事件注册系统生成注册人标识数据。

    Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase
    9.
    发明申请
    Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase 审中-公开
    核苷衍生物作为rna依赖性rna病毒聚合酶的抑制剂

    公开(公告)号：US20060264389A1

    公开(公告)日：2006-11-23

    申请号：US10521006

    申请日：2003-07-11

    申请人： Balkrishen Bhat ,  Steven Carroll ,  Anne Eldrup ,  Malcolm MacCoss ,  David Olsen ,  Thazha Prakash

    发明人： Balkrishen Bhat ,  Steven Carroll ,  Anne Eldrup ,  Malcolm MacCoss ,  David Olsen ,  Thazha Prakash

    IPC分类号： A61K31/7076 ,  C07H19/22

    CPC分类号： C07H19/14 ,  C07H19/22

    摘要： Thee present invention provides nucleoside compounds and certain derivatives thereof which are inhibitors of RNA-dependent RNA viral polymerase. These compounds are inhibitors of RNA-dependent RNA via replication and are useful for the treatment of RNA-dependent RNA viral infection. They are particularly useful as inhibitors of hepatitis C virus (HCV) NS5B polymerase, as inhibitors of HCV replication, and/or for the treatment of hepatitis C infection. The invention also describes pharmaceutical compositions containing such nucleoside compounds alone or in combination with other agents active against RNA-dependent RNA viral infection, in particular HCV infection. Also disclosed are methods of inhibiting RNA-dependent RNA polymerase, inhibiting RNA-dependent RNA viral replication, and/or creating RNA-dependent RNA viral infection with the nucleoside compounds of the present invention.

    摘要翻译： 本发明提供作为RNA依赖性RNA病毒聚合酶抑制剂的核苷化合物及其某些衍生物。 这些化合物是通过复制的RNA依赖性RNA的抑制剂，并且可用于治疗RNA依赖性RNA病毒感染。 它们特别可用作丙型肝炎病毒（HCV）NS5B聚合酶的抑制剂，作为HCV复制的抑制剂和/或用于治疗丙型肝炎感染。 本发明还描述了单独或与其它对RNA依赖性RNA病毒感染（特别是HCV感染）有活性的试剂组合的药物组合物。 还公开了抑制RNA依赖性RNA聚合酶，抑制RNA依赖性RNA病毒复制和/或用本发明的核苷化合物产生RNA依赖性RNA病毒感染的方法。