公开(公告)号：US20060079489A1

公开(公告)日：2006-04-13

申请号：US11292695

申请日：2005-12-02

申请人： Martin Redmon ,  Hal Butler ,  Stephen Wald ,  Paul Rubin

发明人： Martin Redmon ,  Hal Butler ,  Stephen Wald ,  Paul Rubin

IPC分类号： A61K31/473 ,  A61K31/60 ,  A61K31/16 ,  A61K31/192

CPC分类号： A61K31/621 ,  A61K9/2009 ,  A61K9/2013 ,  A61K9/2018 ,  A61K9/2054 ,  A61K9/2059 ,  A61K31/16 ,  A61K31/445 ,  A61K31/4545 ,  A61K31/473 ,  A61K31/60 ,  A61K2300/00

摘要： Stable pharmaceutical compositions of descarboethoxyloratadine (DCL), a metabolic derivative of loratadine, for the treatment of allergic rhinitis and other histamine-induced disorders are disclosed. The compositions are formulated to avoid the incompatibility between DCL and reactive excipients such as lactose and other mono- and di-saccharides. Disclosed compositions include lactose-free, non-hygroscopic and anhydrous stable pharmaceutical compositions of DCL.