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公开(公告)号：US07968856B2
公开(公告)日：2011-06-28
申请号：US12387759
申请日：2009-05-06
申请人： Jerald D. Lee , Stanley D. Dabell
发明人： Jerald D. Lee , Stanley D. Dabell
IPC分类号： G01N21/64
CPC分类号： G01N21/6452 , B01L7/52 , B01L2300/0654 , B01L2300/1805 , G01N21/6428 , G01N21/6456 , G01N2201/062 , Y10T436/143333
摘要： This invention concerns a fluorometer preferably combined with a thermal cycler useful in biochemical protocols such as polymerase chain reaction (PCR) and DNA melting curve analysis. The present fluorometer features a low heat-generating light source such as a light emitting diode (LED), having a one-to-one correspondence to each of a plurality of sample containers, such as capped PCR tubes in a standard titer tray. The fluorometer of the present invention further comprises an optical path between each LED and its correspondingly positioned container, and another optical path between each fluorescing sample within the positioned container and an optical signal sensing means. The instrument can be computer controlled.
摘要翻译： 本发明涉及一种荧光计，优选与可用于生物化学方案如PCR聚合酶链反应（PCR）和DNA熔解曲线分析的热循环仪组合。 本发明的荧光计具有诸如发光二极管（LED）的低发热光源，其与多个样品容器中的每一个具有一一对应关系，例如标准滴定盘中的封盖PCR管。 本发明的荧光计还包括在每个LED和其相应定位的容器之间的光路，以及在定位的容器内的每个荧光样品和光信号感测装置之间的另一光路。 仪器可以由电脑控制。
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公开(公告)号：US20090230323A1
公开(公告)日：2009-09-17
申请号：US12387759
申请日：2009-05-06
申请人： Jerald D. Lee , Stanley D. Dabell
发明人： Jerald D. Lee , Stanley D. Dabell
IPC分类号： G01J1/58
CPC分类号： G01N21/6452 , B01L7/52 , B01L2300/0654 , B01L2300/1805 , G01N21/6428 , G01N21/6456 , G01N2201/062 , Y10T436/143333
摘要： This invention concerns a fluorometer preferably combined with a thermal cycler useful in biochemical protocols such as polymerase chain reaction (PCR) and DNA melting curve analysis. The present fluorometer features a low heat-generating light source such as a light emitting diode (LED), having a one-to-one correspondence to each of a plurality of sample containers, such as capped PCR tubes in a standard titer tray. The fluorometer of the present invention further comprises an optical path between each LED and its correspondingly positioned container, and another optical path between each fluorescing sample within the positioned container and an optical signal sensing means. The instrument can be computer controlled.
摘要翻译： 本发明涉及一种荧光计，优选与可用于生物化学方案如PCR聚合酶链反应（PCR）和DNA熔解曲线分析的热循环仪组合。 本发明的荧光计具有诸如发光二极管（LED）的低发热光源，其与多个样品容器中的每一个具有一一对应关系，例如标准滴定盘中的封盖PCR管。 本发明的荧光计还包括在每个LED和其相应定位的容器之间的光路，以及在定位的容器内的每个荧光样品和光信号感测装置之间的另一光路。 仪器可以由电脑控制。
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公开(公告)号：US20110207142A1
公开(公告)日：2011-08-25
申请号：US13102634
申请日：2011-05-06
申请人： Jerald D. Lee , Stanley D. Dabell
发明人： Jerald D. Lee , Stanley D. Dabell
CPC分类号： G01N21/6452 , B01L7/52 , B01L2300/0654 , B01L2300/1805 , G01N21/6428 , G01N21/6456 , G01N2201/062 , Y10T436/143333
摘要： This invention concerns a fluorometer preferably combined with a thermal cycler useful in biochemical protocols such as polymerase chain reaction (PCR) and DNA melting curve analysis. The present fluorometer features a low heat-generating light source such as a light emitting diode (LED), having a one-to-one correspondence to each of a plurality of sample containers, such as capped PCR tubes in a standard titer tray. The fluorometer of the present invention further comprises an optical path between each LED and its correspondingly positioned container, and another optical path between each fluorescing sample within the positioned container and an optical signal sensing means. The instrument can be computer controlled.
摘要翻译： 本发明涉及一种荧光计，优选与可用于生物化学方案如PCR聚合酶链反应（PCR）和DNA熔解曲线分析的热循环仪组合。 本发明的荧光计具有诸如发光二极管（LED）的低发热光源，其与多个样品容器中的每一个具有一一对应关系，例如标准滴定盘中的封盖PCR管。 本发明的荧光计还包括在每个LED和其相应定位的容器之间的光路，以及在定位的容器内的每个荧光样品和光信号感测装置之间的另一光路。 仪器可以由电脑控制。
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公开(公告)号：US07109495B2
公开(公告)日：2006-09-19
申请号：US10863535
申请日：2004-06-08
申请人： Jerald D. Lee , Stanley D. Dabell
发明人： Jerald D. Lee , Stanley D. Dabell
IPC分类号： G21K5/00
CPC分类号： G01N21/6452 , B01L7/52 , B01L2300/0654 , B01L2300/1805 , G01N21/6428 , G01N21/6456 , G01N2201/062 , Y10T436/143333
摘要： This invention concerns a fluorometer preferably combined with a thermal cycler useful in biochemical protocols such as polymerase chain reaction (PCR) and DNA melting curve analysis. The present fluorometer features a low heat-generating light source such as a light emitting diode (LED), having a one-to-one correspondence to each of a plurality of sample containers, such as capped PCR tubes in a standard titer tray. The fluorometer of the present invention further comprises an optical path between each LED and its correspondingly positioned container, and another optical path between each fluorescing sample within the positioned container and an optical signal sensing means. The instrument can be computer controlled.
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公开(公告)号：US06852986B1
公开(公告)日：2005-02-08
申请号：US10111114
申请日：2000-11-09
申请人： Jerald D. Lee , Stanley D. Dabell
发明人： Jerald D. Lee , Stanley D. Dabell
CPC分类号： G01N21/6452 , B01L7/52 , B01L2300/0654 , B01L2300/1805 , G01N21/6428 , G01N21/6456 , G01N2201/062 , Y10T436/143333
摘要： This invention concerns a fluorometer preferably combined with a thermal cycler useful in biochemical protocols such as polymerase chain reaction (PCR) and DNA melting curve analysis. The present flourometer features a low heat-generating light source such as a light emitting diode (LED), having a one-to-one correspondence to each of a plurality of sample containers, such as capped PCR tubes in a standard titer tray. The flourometer of the present invention further comprises an optical path between each LED and its correspondingly positioned container, and another optical path between each flourescing sample within the positioned container and an optical signal sensing means. The instrument can be computer controlled.
摘要翻译： 本发明涉及一种荧光计，优选与可用于生物化学方案如PCR聚合酶链反应（PCR）和DNA熔解曲线分析的热循环仪组合。 本发明的光学计具有低发热光源，例如发光二极管（LED），其与多个样品容器中的每一个具有一一对应关系，例如在标准滴定盘中的封盖PCR管。 本发明的荧光计还包括在每个LED和其相应定位的容器之间的光路，以及在定位的容器内的每个荧光样品和光信号感测装置之间的另一光路。 仪器可以由电脑控制。
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公开(公告)号：US20120183968A1
公开(公告)日：2012-07-19
申请号：US13351885
申请日：2012-01-17
申请人： Jerald D. Lee , Stanley D. Dabell
发明人： Jerald D. Lee , Stanley D. Dabell
CPC分类号： G01N21/6452 , B01L7/52 , B01L2300/0654 , B01L2300/1805 , G01N21/6428 , G01N21/6456 , G01N2201/062 , Y10T436/143333
摘要： This invention concerns a fluorometer preferably combined with a thermal cycler useful in biochemical protocols such as polymerase chain reaction (PCR) and DNA melting curve analysis. The present fluorometer features a low heat-generating light source such as a light emitting diode (LED), having a one-to-one correspondence to each of a plurality of sample containers, such as capped PCR tubes in a standard titer tray. The fluorometer of the present invention further comprises an optical path between each LED and its to correspondingly positioned container, and another optical path between each fluorescing sample within the positioned container and an optical signal sensing means. The instrument can be computer controlled.
摘要翻译： 本发明涉及一种荧光计，优选与可用于生物化学方案如PCR聚合酶链反应（PCR）和DNA熔解曲线分析的热循环仪组合。 本发明的荧光计具有诸如发光二极管（LED）的低发热光源，其与多个样品容器中的每一个具有一一对应关系，例如标准滴定盘中的封盖PCR管。 本发明的荧光计还包括在每个LED与其对应定位的容器之间的光路，以及在定位的容器内的每个荧光样品与光信号感测装置之间的另一光路。 仪器可以由电脑控制。
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公开(公告)号：US20080212090A1
公开(公告)日：2008-09-04
申请号：US12052212
申请日：2008-03-20
申请人： Jerald D. Lee , Stanley D. Dabell
发明人： Jerald D. Lee , Stanley D. Dabell
IPC分类号： G01J3/30
CPC分类号： G01N21/6452 , B01L7/52 , B01L2300/0654 , B01L2300/1805 , G01N21/6428 , G01N21/6456 , G01N2201/062 , Y10T436/143333
摘要： This invention concerns a fluorometer preferably combined with a thermal cycler useful in biochemical protocols such as polymerase chain reaction (PCR) and DNA melting curve analysis. The present fluorometer features a low heat-generating light source such as a light emitting diode (LED), having a one-to-one correspondence to each of a plurality of sample containers, such as capped PCR tubes in a standard titer tray. The fluorometer of the present invention further comprises an optical path between each LED and its correspondingly positioned container, and another optical path between each fluorescing sample within the positioned container and an optical signal sensing means. The instrument can be computer controlled.
摘要翻译： 本发明涉及一种荧光计，优选与可用于生物化学方案如PCR聚合酶链反应（PCR）和DNA熔解曲线分析的热循环仪组合。 本发明的荧光计具有诸如发光二极管（LED）的低发热光源，其与多个样品容器中的每一个具有一一对应关系，例如标准滴定盘中的封盖PCR管。 本发明的荧光计还包括在每个LED和其相应定位的容器之间的光路，以及在定位的容器内的每个荧光样品和光信号感测装置之间的另一光路。 仪器可以由电脑控制。
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