公开(公告)号：US10647669B2

公开(公告)日：2020-05-12

申请号：US16320712

申请日：2017-06-14

Applicant: SinoNutraceutical Co., Ltd.

Inventor： Maojian Gu ,  Jianmei Su

IPC: A61K9/20 ,  C07C403/24 ,  A61P27/02 ,  A23L33/105 ,  A61K47/12 ,  A61K31/23 ,  A61K47/02 ,  A61K31/047 ,  A61K31/015 ,  A61K47/40 ,  A61K47/26 ,  A61P27/12 ,  A61P27/10 ,  A61K9/00

Abstract: Disclosed in the present invention are a composition containing lutein/lutein ester and applications thereof. Components of the composition containing lutein/lutein ester comprise lutein/lutein ester, β-carotene and a pharmaceutically acceptable carrier. The weight ratio of lutein/lutein ester to β-carotene is 1:0.1-100. In the present invention, by cooperatively using lutein/lutein ester and β-carotene and using auxiliary natural healthy ingredients, the dosage form of an orally disintegrating tablet is prepared. The orally disintegrating tablet is absorbed through the oral cavity, has fast effectiveness and small first-pass effect, reduces damage of gastric acid to lutein/lutein ester, has high bioavailability, and has the characteristics of nutritional and health-care effects, good mouthfeel and fast absorption. By eating the product, visual power can be obviously enhanced, the ocular blood flow is increased, and eye muscle fatigue is alleviated, and accordingly the morbidities of cataract, senile niacula lutea retinae lesion and adolescent myopia are reduced.

公开(公告)号：US20190161441A1

公开(公告)日：2019-05-30

申请号：US16320712

申请日：2017-06-14

Applicant: SinoNutraceutical Co., Ltd.

Inventor： Maojian GU ,  Jianmei SU

IPC: C07C403/24 ,  A23L33/105 ,  A61P27/02 ,  A61K9/20

Abstract: Disclosed in the present invention are a composition containing lutein/lutein ester and applications thereof. Components of the composition containing lutein/lutein ester comprise lutein/lutein ester, β-carotene and a pharmaceutically acceptable carrier. The weight ratio of lutein/lutein ester to β-carotene is 1:0.1-100. In the present invention, by cooperatively using lutein/lutein ester and β-carotene and using auxiliary natural healthy ingredients, the dosage form of an orally disintegrating tablet is prepared. The orally disintegrating tablet is absorbed through the oral cavity, has fast effectiveness and small first-pass effect, reduces damage of gastric acid to lutein/lutein ester, has high bioavailability, and has the characteristics of nutritional and health-care effects, good mouthfeel and fast absorption. By eating the product, visual power can be obviously enhanced, the ocular blood flow is increased, and eye muscle fatigue is alleviated, and accordingly the morbidities of cataract, senile niacula lutea retinae lesion and adolescent myopia are reduced.