Abstract:
A dry powder inhaler has a main airflow path including a cyclone chamber (16) having an air inlet and being so shaped that at least a part of the chamber decreases in cross-sectional area in a direction away from the air inlet, so as thereby in use to set up a reverse flow cyclone in the chamber. A bypass airflow path (8) bypasses the cyclone chamber and the main and bypass airflow paths communicate with a mouthpiece (6). The cyclone chamber may be provided by a part (22) which is removable from the rest of the inhaler for regular replacement thereof.
Abstract:
A method of filling a drug capsule (2) for a dry powder inhaler comprising introducing a dose of powdered active substance (4) into the capsule and introducing a separate quantity of filler particles (6) into the capsule (2), said filler particles being of different composition and having a larger average particle size than the active substance.
Abstract:
A dry powder inhaler comprises two parts (2, 4) connected by an integrally moulded, e.g. living hinge (6), so as to be moveable from an open position to a closed position. At least one of the parts (2, 4) defines at least part of a circulating airflow chamber (12), wherein when said parts (2, 4) are in said closed position, the inhaler comprises an airflow path including the circulating airflow chamber (12).
Abstract:
A dry powder inhaler comprises two parts (2, 4) connected by an integrally molded, e.g. living hinge (6), so as to be moveable from an open position to a closed position. At least one of the parts (2, 4) defines at least part of a circulating airflow chamber (12), wherein when said parts (2, 4) are in said closed position, the inhaler comprises an airflow path including the circulating airflow chamber (12).
Abstract:
The present invention relates to an inhalation-activatable device for administration of medicament in powder form to the respiratory system of a patient.
Abstract:
A dry powder inhaler comprises a main airflow path including a cyclone chamber (16) having an air inlet and being so shaped that at least a part of the chamber decreases in cross-sectional area in a direction away from the air inlet, so as thereby in use to set up a reverse flow cyclone in the chamber. A bypass airflow path (8) bypasses the cyclone chamber and the main and bypass airflow paths communicate with a mouthpiece (6). The cyclone chamber may be provided by a part (22) which is removable from the rest of the inhaler for regular replacement thereof.
Abstract:
The present invention relates to an inhalation-activatable device for administration of medicament in powder form to the respiratory system of a patient.
Abstract:
A dry powder inhaler comprises: a cyclone chamber having a cyclone chamber outlet (20) extending substantially axially therefrom; a mouthpiece channel (26) having a central axis; and a plenum portion (58) connecting said cyclone chamber outlet (20) and said mouthpiece channel, the mouthpiece channel axis Am being offset from, and making a non-parallel angle with, the axis of the cyclone outlet Ac such that in use air exits the cyclone outlet (20) at least partly tangentially into the mouthpiece (28). Also disclosed is a blister pack (200) for use with a dry powder inhaler and including a dose of powder for inhalation, the blister comprising: a base part (202) comprising at least one chamber (204,206); a grommet cover (208) extending partly over said chamber and defining an aperture (212, 214) above the chamber; and a protective layer (210) covering at least said aperture, wherein the edge of the grommet cover (208) defining the aperture (212, 214) is compliant so as in use to form a seal around a tube passing through the aperture.
Abstract:
An inhaler for dispensing medicament in the form of a dry powder is powder is provided with an airway (50) through which a dose travels from an ejection zone to an outlet of the airway. The airway (50) has an inlet means which is so arranged as to create a jacket of air, flowing through a part of the airway extending from the ejection zone to the outlet. The jacket of air surrounds said dose and thereby prevents it form impinging on the airway walls. This reduces accumulation of material on the airway walls, and thus improves the consistency of performance of the inhaler. Preferably, the inlet means includes a throat for producing a stream of fast flowing air which creates a zone of low pressure in front of the ejection zone, thereby to facilitate ejection of a dose.