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1.发明申请2' and 3'-Substituted Cyclobutyl Nucleoside Analogs for the Treatment Viral Infections and Abnormal Cellular Proliferation 有权2'和3'-取代的环丁基核苷类似物用于治疗病毒感染和异常细胞增殖公开(公告)号：US20090149416A1
公开(公告)日：2009-06-11
申请号：US12368876
申请日：2009-02-10
申请人： Dennis C. Liotta , Shuli Mao , Michael Hager
发明人： Dennis C. Liotta , Shuli Mao , Michael Hager
IPC分类号： A61K31/708 , C07H19/02 , A61K31/7076 , A61P31/18 , A61K31/706
摘要： Provided are cyclobutyl nucleosides and methods for their use in treatment of infections including Retroviridae (including HIV), Hepadnaviridae (including HBV), or Flaviviridae (including BVDV and HCV) infection, or conditions related to abnormal cellular proliferation, in a host, including animals, and especially humans.
摘要翻译： 提供的环丁基核苷及其用于治疗感染的方法，包括逆转录病毒科（包括HIV），肝炎病毒科（包括HBV）或黄病毒科（包括BVDV和HCV）感染或与异常细胞增殖有关的病症，包括动物 ，特别是人类。
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2.发明授权2′ and 3′-substituted cyclobutyl nucleoside analogs for the treatment of viral infections and abnormal cellular proliferation 有权2'和3'-取代的环丁基核苷类似物用于治疗病毒感染和异常细胞增殖公开(公告)号：US07495006B2
公开(公告)日：2009-02-24
申请号：US11301326
申请日：2005-12-08
申请人： Dennis C. Liotta , Shuli Mao , Michael Hager
发明人： Dennis C. Liotta , Shuli Mao , Michael Hager
IPC分类号： A61K31/505 , A61K31/506 , A61K31/513 , A61K31/52 , A61K31/522 , C07F9/113 , C07F9/117 , C07D239/47 , C07D239/48 , C07D473/02 , C07D473/04 , C07D473/18 , C07D473/26 , C07D473/32 , C07D473/34
摘要： Provided are cyclobutyl nucleosides and methods for their use in treatment of infections including Retroviridae (including HIV), Hepadnaviridae (including HBV), or Flaviviridae (including BVDV and HCV) infection, or conditions related to abnormal cellular proliferation, in a host, including animals, and especially humans.
摘要翻译： 提供的环丁基核苷及其用于治疗感染的方法，包括逆转录病毒科（包括HIV），肝炎病毒科（包括HBV）或黄病毒科（包括BVDV和HCV）感染或与异常细胞增殖有关的病症，包括动物 ，特别是人类。
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3.发明申请2' and 3'- substituted cyclobutyl nucleoside analogs for the treatment of viral infections and abnormal cellular proliferation 有权2'和3'-取代的环丁基核苷类似物用于治疗病毒感染和异常细胞增殖公开(公告)号：US20060223835A1
公开(公告)日：2006-10-05
申请号：US11301326
申请日：2005-12-08
申请人： Dennis Liotta , Shuli Mao , Michael Hager
发明人： Dennis Liotta , Shuli Mao , Michael Hager
IPC分类号： A61K31/522 , A61K31/52 , A61K31/517 , C07D473/02 , C07D409/02
摘要： Provided are cyclobutyl nucleosides and methods for their use in treatment of infections including Retroviridae (including HIV), Hepadnaviridae (including HBV), or Flaviviridae (including BVDV and HCV) infection, or conditions related to abnormal cellular proliferation, in a host, including animals, and especially humans.
摘要翻译： 提供的环丁基核苷及其用于治疗感染的方法，包括逆转录病毒科（包括HIV），肝炎病毒科（包括HBV）或黄病毒科（包括BVDV和HCV）感染或与异常细胞增殖有关的病症，包括动物 ，特别是人类。
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4.发明授权2′ and 3′-substituted cyclobutyl nucleoside analogs for the treatment viral infections and abnormal cellular proliferation 有权2'和3'-取代的环丁基核苷类似物用于治疗病毒感染和异常细胞增殖公开(公告)号：US08114994B2
公开(公告)日：2012-02-14
申请号：US12368876
申请日：2009-02-10
申请人： Dennis C. Liotta , Shuli Mao , Michael Hager , Raymond F Schinazi
发明人： Dennis C. Liotta , Shuli Mao , Michael Hager , Raymond F Schinazi
IPC分类号： A61K31/505 , A61K31/513 , A61K31/52 , C07D473/18 , C07D473/34 , C07D239/47 , C07D239/54
摘要： Provided are cyclobutyl nucleosides and methods for their use in treatment of infections including Retroviridae (including HIV), Hepadnaviridae (including HBV), or Flaviviridae (including BVDV and HCV) infection, or conditions related to abnormal cellular proliferation, in a host, including animals, and especially humans.
摘要翻译： 提供的环丁基核苷及其用于治疗感染的方法，包括逆转录病毒科（包括HIV），肝炎病毒科（包括HBV）或黄病毒科（包括BVDV和HCV）感染或与异常细胞增殖有关的病症，包括动物 ，特别是人类。
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