Fluorinated quinolones as antimitotic and antitumor agents
    1.
    发明授权
    Fluorinated quinolones as antimitotic and antitumor agents 失效
    氟化喹诺酮作为抗生素和抗肿瘤剂

    公开(公告)号:US06569870B1

    公开(公告)日:2003-05-27

    申请号:US09669155

    申请日:2000-09-25

    IPC分类号: A61K3147

    CPC分类号: C07D491/04 C07D215/38

    摘要: The present invention provides fluorinated quinolones which are fluorinated on the phenyl group thereof, along with pharmaceutical formulations containing the same, methods of treating tumors or cancer by the administration of such compounds, and methods of inhibiting cellular mitosis by the administration of such compounds.

    摘要翻译: 本发明提供了在其苯基上氟化的氟化喹诺酮以及含有其的药物制剂,通过施用这些化合物治疗肿瘤或癌症的方法,以及通过施用这些化合物抑制细胞有丝分裂的方法。