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公开(公告)号：US20110212531A1
公开(公告)日：2011-09-01
申请号：US13093576
申请日：2011-04-25
Applicant: Mario Cindric , Sandra Kraljevic Pavelic , Anita Horvatic , Ivana Dodig
Inventor： Mario Cindric , Sandra Kraljevic Pavelic , Anita Horvatic , Ivana Dodig
IPC: G01N27/00
CPC classification number: G01N33/6848 , C07K1/107 , G01N33/6824 , G01N33/6851 , G01N2458/15 , Y10T436/24 , Y10T436/25
Abstract: A method of detection of amino acid sequences and/or identification of proteins and peptides is based on derivatization of peptides or proteins using compounds comprising two or more sulfonyl groups, and subsequent analysis of the derivatized analytes using a mass spectrometer in its negative mode of operation.
Abstract translation: 检测氨基酸序列和/或鉴定蛋白质和肽的方法是基于使用包含两个或更多个磺酰基的化合物对肽或蛋白质的衍生化，并且使用在其负操作模式中的质谱仪随后分析衍生的分析物 。
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2.发明授权Mass spectrometry-based protein identification method with selective N-terminus derivatization 有权基于质谱法的蛋白质鉴定方法，具有选择性的N末端衍生化公开(公告)号：US08647880B2
公开(公告)日：2014-02-11
申请号：US13093576
申请日：2011-04-25
Applicant: Mario Cindric , Sandra Kraljevic Pavelic , Anita Horvatic , Ivana Dodig
Inventor： Mario Cindric , Sandra Kraljevic Pavelic , Anita Horvatic , Ivana Dodig
CPC classification number: G01N33/6848 , C07K1/107 , G01N33/6824 , G01N33/6851 , G01N2458/15 , Y10T436/24 , Y10T436/25
Abstract: A method of detection of amino acid sequences and/or identification of proteins and peptides is based on derivatization of peptides or proteins using compounds comprising two or more sulfonyl groups, and subsequent analysis of the derivatized analytes using a mass spectrometer in its negative mode of operation.
Abstract translation: 检测氨基酸序列和/或鉴定蛋白质和肽的方法是基于使用包含两个或更多个磺酰基的化合物对肽或蛋白质的衍生化，并且使用在其负操作模式中的质谱仪随后分析衍生的分析物 。
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