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    Systems and methods for the treatment of pain through neural fiber stimulation
    1.
    发明授权
    Systems and methods for the treatment of pain through neural fiber stimulation 有权

    公开(公告)号：US10857361B2

    公开(公告)日：2020-12-08

    申请号：US15651395

    申请日：2017-07-17

    申请人： SPR Therapeutics, LLC

    发明人： Maria E. Bennett ,  Joseph W. Boggs, II ,  Warren M. Grill ,  John Chae

    IPC分类号： A61N1/36

    摘要： Embodiments of the present invention provide systems and methods for the treatment of pain through activation of select neural fibers. The neural fibers may comprise one or more afferent neural fibers and/or one or more efferent neural fibers. If afferent fibers are stimulated, alone or in combination with efferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate afferent pathways in a manner approximating natural afferent activity. The afferent fibers may be associated with primary receptors of muscle spindles, golgi tendon organs, secondary receptors of muscle spindles, joint receptors, touch receptors, and other types of mechanoreceptors and/or proprioceptors. If efferent fibers are stimulated, alone or in combination with afferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate intrafusal and/or extrafusal muscle fibers, which results in an indirect activation of afferent fibers associated therewith.

    SYSTEM AND METHOD FOR TREATMENT OF PAIN RELATED TO LIMB JOINT REPLACEMENT SURGERY
    4.
    发明申请
    SYSTEM AND METHOD FOR TREATMENT OF PAIN RELATED TO LIMB JOINT REPLACEMENT SURGERY 有权
    用于治疗与LIMB关节置换手术相关的疼痛的系统和方法

    公开(公告)号：US20150073496A1

    公开(公告)日：2015-03-12

    申请号：US14547493

    申请日：2014-11-19

    申请人： SPR Therapeutics, LLC

    发明人： Joseph W. Boggs, II ,  Maria E. Bennett ,  Amorn Wongsarnpigoon ,  John Chae ,  Warren M. Grill ,  Kathryn Stager ,  Rosemary Zang

    IPC分类号： A61N1/36 ,  A61N1/05 ,  A61B17/34

    CPC分类号： A61N1/36021 ,  A61B17/3468 ,  A61N1/0502 ,  A61N1/0558 ,  A61N1/36017 ,  A61N1/36071

    摘要： It has been discovered that pain felt in a given region of the body can be treated by stimulating a peripheral nerve at a therapeutically effective distance from the region where pain is felt to generate a comfortable sensation (i.e., paresthesia) overlapping the regions of pain. A method has been developed to reduce pain in a painful region following limb joint replacement by stimulating a peripheral nerve innervating the painful region with an electrode inserted into tissue and spaced from the peripheral nerve. This method may be used to help alleviate postoperative pain in patients following total knee arthroplasty surgery or other limb joint replacement surgeries.

    摘要翻译： 已经发现，可以通过在与感觉到疼痛的区域的治疗有效距离处刺激周围神经以产生与疼痛区域重叠的舒适感觉（即感觉异常）来治疗身体的给定区域中的疼痛。 已经开发了一种方法，通过用插入组织中的电极刺激周围神经支配疼痛区域并与周围神经间隔开来，减轻肢体关节置换后疼痛区域的疼痛。 该方法可用于帮助减轻全膝关节置换手术或其他肢体关节置换手术后患者的术后疼痛。

    System and method for treatment of pain related to limb joint replacement surgery
    5.
    发明授权
    System and method for treatment of pain related to limb joint replacement surgery 有权
    肢体关节置换手术治疗疼痛的系统和方法

    公开(公告)号：US08965516B2

    公开(公告)日：2015-02-24

    申请号：US13791710

    申请日：2013-03-08

    申请人： SPR Therapeutics, LLC

    发明人： Maria E. Bennett ,  Joseph W. Boggs ,  Amorn Wongsarnpigoon ,  John Chae ,  Warren P. Grill ,  Kathryn Stager ,  Rosemary Zang

    IPC分类号： A61N1/05 ,  A61N1/36

    CPC分类号： A61N1/36021 ,  A61B17/3468 ,  A61N1/0502 ,  A61N1/0558 ,  A61N1/36017 ,  A61N1/36071

    摘要： It has been discovered that pain felt in a given region of the body can be treated by stimulating a peripheral nerve at a therapeutically effective distance from the region where pain is felt to generate a comfortable sensation (i.e., paresthesia) overlapping the regions of pain. A method has been developed to reduce pain in a painful region following limb joint replacement by stimulating a peripheral nerve innervating the painful region with an electrode inserted into tissue and spaced from the peripheral nerve. This method may be used to help alleviate postoperative pain in patients following total knee arthroplasty surgery or other limb joint replacement surgeries.

    摘要翻译： 已经发现，可以通过在与感觉到疼痛的区域的治疗有效距离处刺激周围神经以产生与疼痛区域重叠的舒适感觉（即感觉异常）来治疗身体的给定区域中的疼痛。 已经开发了一种方法，通过用插入组织中的电极刺激周围神经支配疼痛区域并与周围神经间隔开来，减轻肢体关节置换后疼痛区域的疼痛。 该方法可用于帮助减轻全膝关节置换手术或其他肢体关节置换手术后患者的术后疼痛。

    Apparatus and method for treating headaches
    7.
    发明授权
    Apparatus and method for treating headaches 有权

    公开(公告)号：US11235146B2

    公开(公告)日：2022-02-01

    申请号：US15533170

    申请日：2015-12-10

    申请人： SPR Therapeutics, LLC

    发明人： Joseph W. Boggs, II ,  Amorn Wongsarnpigoon

    IPC分类号： A61N1/05 ,  A61N1/36

    摘要： The present disclosure generally relates to a system for treating headaches and other pain associated with the occipital nerves. More particularly, the disclosure relates to a system of treating pain by selectively activating specific nerve fibers with a single, fault-resistant contact situated proximate to, but not in direct contact with, portions of one or more the occipital nerves. Additional measures ensure the lead does not migrate or fracture, resulting in long-lasting pain relief.

    Systems and methods for the treatment of pain through neural fiber stimulation of efferent nerve fiber
    9.
    发明授权
    Systems and methods for the treatment of pain through neural fiber stimulation of efferent nerve fiber 有权

    公开(公告)号：US09616229B2

    公开(公告)日：2017-04-11

    申请号：US14336633

    申请日：2014-07-21

    申请人： SPR Therapeutics, LLC

    发明人： Maria E. Bennett ,  Joseph W. Boggs, II ,  Warren M. Grill ,  John Chae

    IPC分类号： A61N1/05 ,  A61N1/36

    CPC分类号： A61N1/36071 ,  A61N1/36003 ,  A61N1/36017 ,  A61N1/36021 ,  A61N1/36057

    摘要： Embodiments of the present invention provide systems and methods for the treatment of pain through activation of select neural fibers. The neural fibers may comprise one or more afferent neural fibers and/or one or more efferent neural fibers. If afferent fibers are stimulated, alone or in combination with efferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate afferent pathways in a manner approximating natural afferent activity. The afferent fibers may be associated with primary receptors of muscle spindles, golgi tendon organs, secondary receptors of muscle spindles, joint receptors, touch receptors, and other types of mechanoreceptors and/or proprioceptors. If efferent fibers are stimulated, alone or in combination with afferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate intrafusal and/or extrafusal muscle fibers, which results in an indirect activation of afferent fibers associated therewith.

    Systems and methods for treating shoulder pain related to subacromial impingement syndrome
    10.
    发明授权
    Systems and methods for treating shoulder pain related to subacromial impingement syndrome 有权
    与肩峰下冲击综合征有关的肩部疼痛的系统和方法

    公开(公告)号：US09381343B2

    公开(公告)日：2016-07-05

    申请号：US14536951

    申请日：2014-11-10

    申请人： SPR Therapeutics, LLC

    发明人： Maria E. Bennett ,  Joseph W. Boggs, II ,  John Chae

    IPC分类号： A61N1/00 ,  A61B18/04 ,  A61B18/18 ,  A61N1/05 ,  A61N1/36 ,  A61N1/04

    CPC分类号： A61N1/0504 ,  A61N1/025 ,  A61N1/0456 ,  A61N1/0502 ,  A61N1/0551 ,  A61N1/08 ,  A61N1/36071

    摘要： Systems and methods are provided for treating chronic pain occurring secondarily to subacromial impingement syndrome in a human body. A system is provided to deliver percutaneous electrical stimulation through at least one electrode to neurological motor points of the posterior and middle deltoid muscles to mediate such pain. One-time, continued and/or periodic dosing of treatment methods according to the present invention may result in a change to central nervous system maladaptive neuroplasticity.

    摘要翻译： 提供的系统和方法用于治疗二次发生在人体内的肩峰下冲击综合征的慢性疼痛。 提供一种系统，用于通过至少一个电极将经皮电刺激递送到后三和三分之一肌肉的神经运动点，以调解这种疼痛。 根据本发明的治疗方法的一次性，持续和/或定期给药可能导致中枢神经系统适应不良的神经可塑性的变化。