摘要:
The invention is directed to 6-(4-pyrimidinyl)-1H-indazole derivatives. Specifically, the invention is directed to compounds according to Formula (I) wherein R1-R4 are defined herein. The compounds of the invention axe inhibitors of PDK1 and can be useful in the treatment of immune and metabolic diseases and disorders characterized by constitutively activated ACG kinases such as cancer and more specifically cancers of the breast, colon, and lung. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting PDK1 activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.
摘要:
A pluggable transceiver module having a housing with a first side and a face perpendicular to the first side, and a tab extending above the surface of the first side sized to mate with a slot in a receptacle for the housing, a wedge slidably mounted on the first side proximate the tab, and a lever attached to the wedge extending beyond the face of the housing, wherein pressing the lever causes the wedge to slide between the tab and the slot on the receptacle and remove the tab from within the slot, thereby releasing the transceiver module from the receptacle, and the lever further including a recess enabling a person to at least partially insert a fingernail to easily grip and remove the pluggable transceiver module from the receptacle.
摘要:
A device including two modules is provided for transferring data signals from a first transmission medium to a second transmission medium. One module includes a conductive housing having a first end and a second end. An electrical connector is mounted at the first end of the housing and is configured to mate to a corresponding connector associated with the first transmission medium. The housing includes a flexible metallic shielded cable extending from the second end. The remote end of the shielded cable is connected to the second module which is configured to mate to a corresponding connector associated with the second transmission medium. The device is pluggable into two system hosts, simultaneously. The modules are each hot pluggable. The device acts as a serial patch cord between the two system hosts, with a standard form factor module plugged into the system hosts at either end.
摘要:
The transceiver includes a housing, a transmitting optical sub-assembly mounted in the housing, a receiving optical sub-assembly mounted in the housing, a first electrical connector associated with the transmitting optical sub-assembly, a second electrical connector associated with the receiving optical sub-assembly, and an electro-magnetic shield mounted on the housing. The housing includes a first fiber optic connector receptacle, a second fiber optic connector receptacle, and a first side, and the housing is made of an electrically conductive material.
摘要:
The invention relates to an interface module, such as a Giga-Bit Interface Converter module, provided to mate within a host device chassis where, at the rear of the mounting slot, a first connector engages a host socket of the host device. According to the invention, the first connector include sequential mating contact traces on a contact beam of a substrate such that when the module is inserted into the corresponding host socket, certain contacts are connected in a pre-defined sequence such that a first set of contacts electrically engages prior to a second set of contacts which electrically engages prior to a third set of contacts. In further accord with the present invention, the first set of contacts includes grounding contacts, the second set includes contacts for powering the substrate and the third set includes signal contacts. An advantage of this sequence is that the GBIC is grounded before it is powered and powered before it begins passing signals thus eliminating the damage to the GBIC encountered under the GBIC-to-host contact sequence given in the prior art GBIC specification.
摘要:
An interface converter module is provided for converting data signals from a first transmission medium to a second transmission medium. The module includes a metallized housing having a first end and a second end. A shielded electrical connector is mounted at the first end of the housing and configured to mate to a corresponding host connector associated with a first transmission medium. The housing includes a flexible metallic shielded cable extending from the second end. The remote end of the shielded cable comprises the media interface which includes an interface connector configured to the connect flexible shielded cable to the second transmission medium. A printed circuit board is mounted within the housing and has mounted thereon electronic circuitry configured to convert data signals from a host device transmission medium to the second transmission medium.
摘要:
The present invention is a method and apparatus which is used to enable application developers to generate workflow enabled applications which request services from the workflow server component of the workflow system, remotely and indirectly using messaging, shared databases or inter-process communications. The present invention provides a standard transaction format (STF) for accessing such a workflow system through STF processors via messaging, updates to the shared databases or inter-process communications. Workflow enabled applications are used by users to act and participate in business processes and enable users and managers to observe and query the status of workflows and business processes.
摘要:
An interface converter module includes a metallized housing having a first end and a second end. A printed circuit board is mounted within the housing and has mounted thereon electronic circuitry configured to convert data signals from a host device transmission medium to the second transmission medium. The printed circuit board has not more than twenty contact fingers adhered at one end in order to form a host connector, a media connector is at the other end of the module. The media end having a dual LC duplex optical receptacle, where each duplex portion of the dual LC duplex optical receptacle houses a ROSA and a TOSA. The module and receiver may include interengaging rails and slots and/or keys and keyways to ensure correct matching of modules and receptacles.
摘要:
A transceiver module having a housing with a first side and a face perpendicular to the first side, and a tab extending above the surface of the first side sized to mate with a slot in a receptacle for the housing, a wedge slidably mounted on the first side proximate the tab, and a release lever attached to the wedge extending beyond the face of the housing, wherein pressing the release lever causes the wedge to slide between the tab and the slot on the receptacle and remove the tab from within the slot, thereby releasing the transceiver module from the receptacle.
摘要:
A device which is surface mountable to a printed circuit board. The device includes a housing, an optical sub-assembly, and an electrical connector. The housing includes a fiber optic connector receptacle and a bottom side. The housing is made of an electrically conductive material. The optical sub-assembly is associated with the fiber optic connector receptacle. The electrical connector has contacts, where some portions of the contacts extend into the housing and some portions of the contacts extend from the housing. A portion of the contacts being in a same plane with the bottom side of the housing.