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公开(公告)号：US20080008743A1
公开(公告)日：2008-01-10
申请号：US11774292
申请日：2007-07-06
申请人： Mahendra Dedhiya , Anil Chhettry , Ranajoy Sarkar
发明人： Mahendra Dedhiya , Anil Chhettry , Ranajoy Sarkar
CPC分类号： A61K31/13 , A61K9/0053 , A61K9/0056 , A61K9/2027 , A61K9/205 , A61K9/2054 , A61K9/7007 , A61K47/10 , A61K47/32 , A61K47/40 , Y02A50/411
摘要： Orally dissolving formulations, e.g., tablets (ODTs) and films (ODFs) comprising memantine and methods of treating conditions, including childhood behavioral disorders and Alzheimer's disease, by administering orally dissolving formulations are provided. The orally dissolving formulations of the present invention may be used to treat various conditions, but is particularly suited to treat childhood behavioral disorders, such as autistic spectrum disorders or combined type Attention-Deficit/Hyperactivity Disorder (ADHD) and also to treat elderly patients suffering from Alzheimer's disease.
摘要翻译： 提供口服溶解制剂，例如包含美金刚的片剂（ODT）和膜（ODF）和治疗病症的方法，包括儿童期行为障碍和阿尔茨海默氏病。 本发明的口服溶解制剂可用于治疗各种病症，但特别适用于治疗儿童行为障碍，例如自闭症谱系障碍或组合型注意力缺陷/多动障碍（ADHD），并且还可治疗患有老年患者 来自阿尔茨海默病。
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公开(公告)号：US20110046232A1
公开(公告)日：2011-02-24
申请号：US12888513
申请日：2010-09-23
IPC分类号： A61K31/13 , C07C211/38 , A61P25/28 , A61P25/00
CPC分类号： A61K31/13 , A61K9/0053 , A61K9/0056 , A61K9/2027 , A61K9/205 , A61K9/2054 , A61K9/7007 , A61K47/10 , A61K47/32 , A61K47/40 , Y02A50/411
摘要： Orally dissolving formulations, e.g., tablets (ODTs) and films (ODFs) comprising memantine and methods of treating conditions, including childhood behavioral disorders and Alzheimer's disease, by administering orally dissolving formulations are provided. The orally dissolving formulations of the present invention may be used to treat various conditions, but is particularly suited to treat childhood behavioral disorders, such as autistic spectrum disorders or combined type Attention-Deficit/Hyperactivity Disorder (ADHD) and also to treat elderly patients suffering from Alzheimer's disease.
摘要翻译： 提供口服溶解制剂，例如包含美金刚的片剂（ODT）和膜（ODF）和治疗病症的方法，包括儿童期行为障碍和阿尔茨海默氏病。 本发明的口服溶解制剂可用于治疗各种病症，但特别适用于治疗儿童行为障碍，例如自闭症谱系障碍或组合型注意力缺陷/多动障碍（ADHD），并且还可治疗患有老年患者 来自阿尔茨海默病。
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公开(公告)号：US20100016334A1
公开(公告)日：2010-01-21
申请号：US12504149
申请日：2009-07-16
IPC分类号： A61K31/495 , C07D295/135
CPC分类号： C07D295/135 , A61K9/2018 , A61K9/4858 , A61K9/4866 , A61K31/495
摘要： The present invention relates to stable and bioavailable immediate release formulations comprising dopamine receptor ligands. Methods of treating various disorders by administering the formulations are also described.
摘要翻译： 本发明涉及包含多巴胺受体配体的稳定和生物可利用的速释制剂。 还描述了通过施用制剂治疗各种疾病的方法。
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公开(公告)号：US09056845B2
公开(公告)日：2015-06-16
申请号：US12504149
申请日：2009-07-16
IPC分类号： A61K31/495 , C07D295/135 , A61K9/20 , A61K9/48
CPC分类号： C07D295/135 , A61K9/2018 , A61K9/4858 , A61K9/4866 , A61K31/495
摘要： The present invention relates to stable and bioavailable immediate release formulations comprising dopamine receptor ligands. Methods of treating various disorders by administering the formulations are also described.
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公开(公告)号：US20090247644A1
公开(公告)日：2009-10-01
申请号：US12412447
申请日：2009-03-27
IPC分类号： A61K31/13
CPC分类号： A61K9/7007 , A61K9/0056 , A61K9/5026 , A61K31/13
摘要： The present invention relates to pharmaceutical compositions prepared from equant-shaped crystals of memantine, such as orally dissolving formulations, e.g., tablets (ODTs) and films (ODFs), and to methods of treating conditions, including childhood behavioral disorders (e.g., autism) and Alzheimer's disease by administering the same.
摘要翻译： 本发明涉及由美金刚的等量形状晶体制备的药物组合物，例如口服溶解制剂，例如片剂（ODT）和膜（ODF），以及治疗包括儿童期行为障碍（例如自闭症）在内的病症的方法， 和阿尔茨海默病。
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公开(公告)号：US20130040966A1
公开(公告)日：2013-02-14
申请号：US13653576
申请日：2012-10-17
IPC分类号： A61K31/495 , A61P25/24 , A61P25/18
CPC分类号： C07D295/135 , A61K9/2018 , A61K9/4858 , A61K9/4866 , A61K31/495
摘要： The present invention relates to stable and bioavailable immediate release formulations comprising dopamine receptor ligands. Methods of treating various disorders by administering the formulations are also described.
摘要翻译： 本发明涉及包含多巴胺受体配体的稳定和生物可利用的速释制剂。 还描述了通过施用制剂治疗各种疾病的方法。
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公开(公告)号：US20110165252A1
公开(公告)日：2011-07-07
申请号：US13050139
申请日：2011-03-17
CPC分类号： A61K9/7007 , A61K9/0056 , A61K9/5026 , A61K31/13
摘要： The present invention relates to pharmaceutical compositions prepared from equant-shaped crystals of memantine, such as orally dissolving formulations, e.g., tablets (ODTs) and films (ODFs), and to methods of treating conditions, including childhood behavioral disorders (e.g., autism) and Alzheimer's disease by administering the same.
摘要翻译： 本发明涉及由美金刚的等量形状晶体制备的药物组合物，例如口服溶解制剂，例如片剂（ODT）和膜（ODF），以及治疗包括儿童期行为障碍（例如自闭症）在内的病症的方法， 和阿尔茨海默病。
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