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公开(公告)号：US20050092684A1
公开(公告)日：2005-05-05
申请号：US10981152
申请日：2004-11-03
IPC分类号： A23J20060101 , C02F1/44 , C12P21/06
摘要： A method (100) and a system (200) for processing mammalian bodily fluids to isolate target peptides and proteins. The method can include the steps of passing a mammalian bodily fluid through at least one ion exchange column (204). The ion exchange column can include an anionic resin and/or a cationic resin. The ion exchange column can be selected to remove large particles at a first pH level selected to remove such large particles at a maximum fluid pressure of 30 pounds per square inch (psi), for example less than 10 psi. The large particles can be released from the ion exchange column with a rinse solution having a pH selected for releasing the large particles. The pH of the fluid then can be adjusted to be a value less than 5.0, and the fluid can be filtered with a microfilter or ultrafilter (210).
摘要翻译： 一种用于处理哺乳动物体液以分离靶肽和蛋白质的方法（100）和系统（200）。 该方法可以包括使哺乳动物体液通过至少一个离子交换柱（204）的步骤。 离子交换柱可以包括阴离子树脂和/或阳离子树脂。 可以选择离子交换柱以在选择的第一pH水平下除去大颗粒，以在30磅/平方英寸（psi），例如小于10psi的最大流体压力下除去这种大颗粒。 可以用离子交换柱释放大颗粒，其中所述漂洗溶液具有选择用于释放大颗粒的pH。 然后可以将流体的pH调节为小于5.0的值，并且可以用微过滤器或超滤器（210）过滤流体。
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公开(公告)号：US07547770B2
公开(公告)日：2009-06-16
申请号：US10981152
申请日：2004-11-03
摘要： A method (100) and a system (200) for processing mammalian bodily fluids to isolate target peptides and proteins. The method can include the steps of passing a mammalian bodily fluid through at least one ion exchange column (204). The ion exchange column can include an anionic resin and/or a cationic resin. The ion exchange column can be selected to remove large particles at a first pH level selected to remove such large particles at a maximum fluid pressure of 30 pounds per square inch (psi), for example less than 10 psi. The large particles can be released from the ion exchange column with a rinse solution having a pH selected for releasing the large particles. The pH of the fluid then can be adjusted to be a value less than 5.0, and the fluid can be filtered with a microfilter or ultrafilter (210).
摘要翻译： 一种用于处理哺乳动物体液以分离靶肽和蛋白质的方法（100）和系统（200）。 该方法可包括使哺乳动物体液通过至少一个离子交换柱（204）的步骤。 离子交换柱可以包括阴离子树脂和/或阳离子树脂。 可以选择离子交换柱以在选择的第一pH水平下除去大颗粒，以在30磅/平方英寸（psi），例如小于10psi的最大流体压力下除去这种大颗粒。 可以用离子交换柱释放大颗粒，其中所述漂洗溶液具有选择用于释放大颗粒的pH。 然后可以将流体的pH调节为小于5.0的值，并且可以用微过滤器或超滤器（210）过滤流体。
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公开(公告)号：US5326579A
公开(公告)日：1994-07-05
申请号：US906108
申请日：1992-07-06
CPC分类号： A23C7/043 , A23C15/145 , C11B3/10
摘要： The present invention relates to a process for the removal of cholesterol from a processed or un processed dairy product, which process comprises: (a) obtaining a processed or unprocessed dairy product containing cholesterol (b) contacting the dairy product at a temperature of between about 35.degree. and 80.degree. C. with an amount of saponin effective to bind up to about 90% of the cholesterol present in the dairy product; (c) contacting a temperature of between about 35.degree. and 80.degree. C. the cholesterol:saponin with an effective amount of diatomaceous earth; (d) separating the insoluble cholesterol: saponin/diatomaceous earth by filtration or centrifugation; and (e) recovering the dairy product having a reduced content of cholesterol. The process particularly useful wherein the dairy product is selected form raw milk, pasteurized milk, raw cream, pasteurized cream, butteroil or anhydrous fat. The dairy product having a lowered cholesterol level is useful as a food to restrict cholesterol intake in a human being.
摘要翻译： 本发明涉及一种从加工或未加工的乳制品中去除胆固醇的方法，该方法包括：（a）获得含有胆固醇的加工或未加工的乳制品（b）在约 35℃和80℃，一定量的皂苷有效地结合乳制品中存在的约90％的胆固醇; （c）将约35℃至80℃的温度与胆固醇：皂苷与有效量的硅藻土接触; （d）通过过滤或离心分离不溶性胆固醇：皂角苷/硅藻土; 和（e）回收胆固醇含量降低的乳制品。 该方法特别有用，其中乳制品选自生奶，巴氏消毒牛奶，生奶油，巴氏杀菌奶油，乳油或无水脂肪。 具有降低的胆固醇水平的乳制品可用作限制人体胆固醇摄入的食物。
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公开(公告)号：US4689245A
公开(公告)日：1987-08-25
申请号：US736315
申请日：1985-05-21
CPC分类号： A23C9/152 , A23C9/1422 , A23C9/158
摘要： A coffee whitener composition made from decreamed milk ultrafiltration retentate having its protein concentrated between about 2:1 to about 4:1 compared to the protein content of the starting milk and a minor whitening power enhancing amount is added in the form of riboflavin (a vitamin) and beta carotene (a vitamin precursor) or a mixture thereof. The composition is usually in powdered form and is high in protein, low in fat and sodium and reduced in lactose and its high protein enhanced as described provided a low-fat dairy coffee whitening function approximately equal to non-dairy coffee creamers.
摘要翻译： 以与初始乳的蛋白质含量相比，其蛋白质浓缩约2:1至约4:1的精制牛奶超滤滞留物制成的咖啡增白剂组合物以次黄酸（维生素 ）和β-胡萝卜素（维生素前体）或其混合物。 组合物通常为粉末形式，并且蛋白质高，脂肪和钠低，乳糖降低，并且其高蛋白质如所提及的低脂乳制咖啡增白功能大致相当于非乳制咖啡奶精所述。
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5.发明授权
公开(公告)号：US4689151A
公开(公告)日：1987-08-25
申请号：US736323
申请日：1985-05-21
CPC分类号： A23C9/1422 , B01D61/145 , B01D61/18 , B01D63/02 , B01D63/06 , B01D63/10
摘要： A method of removing penicillin G and/or pharmaceutical antibiotics which contaminated milk by:(a) Subjecting the contaminated milk to an ultrafiltration process which produces a permeate containing the contamining antibiotic and a retentate comprising milk proteins and fats.(b) Adding a non-antibiotic containing retentate diluting (washing) aqueous fluid including uncontaminated ultrafiltered milk permeate, uncontaminated whole milk, uncontaminated skimmilk, or uncontaminated acid or sweet whey, or a mixture thereof to the retentate to dilute the retentate.(c) Subjecting the diluted (washed) retentate to the ultrafiltration process from additional antibiotic containing permeate thereby forming a milk product comprising retentate having a reduced level of or substantially free of antibiotics.(d) After the last dilution (wash) step and the milk retentate is returned to selected protein concentration the retentate is reconstituted with either uncontaminated ultrafiltrated milk permeate, or uncontaminated whole milk, or uncontaminated skimmilk, or acid whey or sweet whey.
摘要翻译： 一种通过以下方式去除青霉素G和/或药物抗生素的方法：（a）将受污染的乳进行超滤过程，其产生含有污染抗生素的渗透物和包含乳蛋白质和脂肪的渗余物。 （b）将非抗生素的渗余物稀释（洗涤）含水流体，包括未被污染的超滤乳渗透物，未污染的全脂牛奶，未污染的撇渣物或未污染的酸或甜乳清，或其混合物稀释至渗余物以稀释滞留物。 （c）将来自额外的含有抗生素的渗透物的稀释（洗涤）滞留物置于超滤过程中，从而形成包含具有降低的或基本上不含抗生素的保留物的乳制品。 （d）在最后一次稀释（洗涤）步骤之后，将乳剩余物返回到选定的蛋白质浓度，用未受污染的超滤乳的渗透物，未受污染的全脂牛奶或未受污染的麸皮，或酸乳清或甜乳清重构滞留物。
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