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公开(公告)号：US07207996B2
公开(公告)日：2007-04-24
申请号：US10115422
申请日：2002-04-04
CPC分类号： A61B17/0482 , A61B5/026 , A61B8/06 , A61B8/12 , A61B17/122 , A61B17/282 , A61B17/42
摘要： A compression and ligation device includes a pair of jaws including one or more Doppler chips oriented to send and receive Doppler signals across the jaws, to assist a practitioner in determining whether or not a uterine artery is between the jaws. A suture leader with an attached suture can be pushed through a channel on one of the jaws, through tissue behind the uterine artery, into another channel on the other jaw, and proximally out the device so that the practitioner can ligate the artery and effect hemostasis.
摘要翻译： 压缩和结扎装置包括一对钳口，包括一个或多个多普勒芯片，其针对跨越钳口发送和接收多普勒信号，以帮助从业者确定子宫动脉是否在钳口之间。 具有连接缝合线的缝合线头可以通过其中一个钳口上的通道，通过子宫动脉后面的组织推入另一个钳口上的另一个通道，并向近端推出该装置，使得医师可以连接动脉并实现止血 。
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公开(公告)号：US07141057B2
公开(公告)日：2006-11-28
申请号：US10666075
申请日：2003-09-18
申请人： Fred Burbank , Michael L. Jones , Jill Uyeno , Greig E. Altieri , R. J. Serra
发明人： Fred Burbank , Michael L. Jones , Jill Uyeno , Greig E. Altieri , R. J. Serra
CPC分类号： A61B17/32056 , A61B17/0469 , A61B17/0482 , A61B17/12009 , A61B18/1477 , A61B18/1482 , A61B2017/00349 , A61B2017/00867 , A61B2017/0472 , A61B2017/06104 , A61B2017/306 , A61B2018/00601 , A61B2018/0063 , A61B2018/126 , A61B2018/1425 , A61B2090/378
摘要： Exemplary embodiments are directed to providing a method of preparing an anatomical vessel contained within a tissue bundle for ligation, including positioning a cannula adjacent to the tissue bundle, wherein the positioning is non-penetrating, the cannula including a first extendable member, a second extendable member, a Doppler wand, and a distal end, transmitting ultrasound signals toward the vessel through the tissue bundle with the Doppler wand, receiving ultrasound signals reflected by the vessel through the tissue bundle with the Doppler wand, invaginating the tissue bundle with the first extendable member on a first side of the tissue bundle, invaginating the tissue bundle with the second extendable member on a second side of the bundle opposite the first side, and interpenetrating a length of ligation material between the first and second extendable members on a side of the vessel opposite the cannula distal end.
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公开(公告)号：US07479145B2
公开(公告)日：2009-01-20
申请号：US10716329
申请日：2003-11-18
申请人： Fred H. Burbank , Michael L. Jones , Greig E. Altieri , R. J. Serra , Ed Olson , Yu-Tung Wong
发明人： Fred H. Burbank , Michael L. Jones , Greig E. Altieri , R. J. Serra , Ed Olson , Yu-Tung Wong
CPC分类号： A61B17/4241 , A61B17/282 , A61B17/42
摘要： The invention is directed to tenaculum-like devices and systems for the intravaginal delivery of therapeutic or diagnostic devices and particularly for occluding a female patient's uterine arteries in order to treat uterine disorders. Included are methods for grasping, manipulating and retaining tissue. The tenaculum-type device has a distal portion with a sound configured to enter a cervical os without causing undue trauma or discomfort to the patient, and a retention or tissue grasping mechanism with a grasping element such as a spike configured to engage and retain a patient's cervix. The tenaculum-type devices embodying features of the invention may have an expandable distal tip to more securely be engaged within the patient's uterine cervical canal.
摘要翻译： 本发明涉及用于治疗或诊断装置的阴道内输送的特定用途的器械和系统，特别是用于阻塞女性患者的子宫动脉以治疗子宫疾病。 包括用于抓握，操纵和保持组织的方法。 所述牵引式装置具有远端部分，其具有构造成进入颈部口的声音，而不会对患者造成不适当的创伤或不适;以及保持或组织夹持机构，其具有抓握元件，例如尖峰，其构造成接合并保持患者的 宫颈。 体现本发明的特征的憩室型装置可以具有可扩张的远端，以更可靠地接合在患者的子宫颈管内。
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4.发明授权Occlusion device with deployable paddles for detection and occlusion of blood vessels 失效闭塞装置具有用于检测和阻塞血管的可展开的桨公开(公告)号：US07354444B2
公开(公告)日：2008-04-08
申请号：US10300116
申请日：2002-11-19
IPC分类号： A61B17/08
CPC分类号： A61B8/06 , A61B5/026 , A61B8/12 , A61B17/00234 , A61B17/122 , A61B17/1227 , A61B17/128 , A61B17/1285 , A61B17/42 , A61B2017/0046
摘要： Devices, systems and methods for temporarily reducing or abolishing blood flow by occluding blood vessels are provided. A blood vessel-occlusion device embodying features of the invention includes a deployable pressure-applying member with a location sensor, and an applicator. The location sensor is configured to detect a blood vessel, which may be occluded by compression from the pressure-applying member. A pressure-applying member may be released from the applicator, with blood-vessel compression maintained after release. The applicator is configured to engage a guide, such as a tenaculum, to aid in the placement and operation of the applicator. A pressure-applying member may also engage the guide. The invention finds use in, for example, treating uterine disorders and conditions which may be treated by occlusion of the uterine arteries, such as uterine fibroids, dysfunctional uterine bleeding, post-partum hemorrhage, and bleeding associated with caesarian section.
摘要翻译： 提供了通过闭塞血管临时减少或消除血流的装置，系统和方法。 体现本发明特征的血管闭塞装置包括具有位置传感器的可部署的施加压力部件和施加器。 位置传感器被配置为检测血管，其可以通过来自压力施加构件的压缩而被阻塞。 压力施加构件可以从施用器释放，释放后保持血管压缩。 施用器被配置成接合引导件，例如构件，以帮助施用器的放置和操作。 压力施加构件还可以接合引导件。 本发明可用于例如治疗可通过闭塞子宫动脉（例如子宫肌瘤），功能失调性子宫出血，产后出血以及与切片相关的出血治疗的子宫疾病和病症。
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公开(公告)号：US06635065B2
公开(公告)日：2003-10-21
申请号：US09909124
申请日：2001-07-17
申请人： Fred Burbank , Michael L. Jones , Jill Uyeno , Greig E. Altieri , R. J. Serra
发明人： Fred Burbank , Michael L. Jones , Jill Uyeno , Greig E. Altieri , R. J. Serra
IPC分类号： A61B1700
CPC分类号： A61B17/32056 , A61B17/0469 , A61B17/0482 , A61B17/12009 , A61B18/1477 , A61B18/1482 , A61B2017/00349 , A61B2017/00867 , A61B2017/0472 , A61B2017/06104 , A61B2017/306 , A61B2018/00601 , A61B2018/0063 , A61B2018/126 , A61B2018/1425 , A61B2090/378
摘要： Exemplary embodiments are directed to providing a method of preparing an anatomical vessel contained within a tissue bundle for ligation, including positioning a cannula adjacent to the tissue bundle, wherein the positioning is non-penetrating, the cannula including a first extendable member, a second extendable member, a Doppler wand, and a distal end, transmitting ultrasound signals toward the vessel through the tissue bundle with the Doppler wand, receiving ultrasound signals reflected by the vessel through the tissue bundle with the Doppler wand, invaginating the tissue bundle with the first extendable member on a first side of the tissue bundle, invaginating the tissue bundle with the second extendable member on a second side of the bundle opposite the first side, and interpenetrating a length of ligation material between the first and second extendable members on a side of the vessel opposite the cannula distal end.
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公开(公告)号：US06638286B1
公开(公告)日：2003-10-28
申请号：US09713020
申请日：2000-11-16
申请人： Fred Burbank , Michael L. Jones , Jill Uyeno , Greig E. Altieri , R. J. Serra
发明人： Fred Burbank , Michael L. Jones , Jill Uyeno , Greig E. Altieri , R. J. Serra
IPC分类号： A61B1708
CPC分类号： A61B17/32056 , A61B17/0469 , A61B17/0482 , A61B17/12009 , A61B18/1477 , A61B18/1482 , A61B2017/00349 , A61B2017/00867 , A61B2017/0472 , A61B2017/06104 , A61B2018/00601 , A61B2018/0063 , A61B2018/126 , A61B2018/1425 , A61B2090/378
摘要： A ligation device includes a cannula having first and second extendable members and a Doppler wand. The Doppler wand permits an anatomical vessel, such as a blood vessel, to be located in close proximity to the distal end of the cannula. The extendable members are extendable on two opposite sides of the vessel. A length of ligation material, such as suture material, extends through the first extendable member, and is attached to a detachable element mounted to the distalmost end of the extendable member. The second extendable member includes a snare. The first extendable member includes curved portions which, when the member is extended distally, extend the detachable element into position for the snare so that the snare can grab the loop. Once ensnared, the detachable element is released from the first extendable member, which pulls the ligation material around the vessel. The ligation device does not require prior visualization or dissection of the area around the vessel.
摘要翻译： 连接装置包括具有第一和第二可延伸构件的插管和多普勒棒。 多普勒手柄允许诸如血管的解剖血管位于紧邻套管远端的位置。 可延伸构件可在容器的两个相对侧上延伸。 连接材料（例如缝合材料）的长度延伸穿过第一可延伸构件，并且附接到安装到可延伸构件的最远端的可拆卸元件。 第二可延伸构件包括圈套。 第一可伸展构件包括弯曲部分，当构件向远侧延伸时，将可拆卸元件延伸到圈套的位置，使得圈套可以抓住环路。 一旦被捕获，可拆卸元件从第一可延伸构件释放，其将结扎材料拉向容器周围。 结扎装置不需要先前可视化或解剖血管周围的区域。
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公开(公告)号：US5681335A
公开(公告)日：1997-10-28
申请号：US509354
申请日：1995-07-31
申请人： R. J. Serra , Blair D. Walker , Scott M. Evans
发明人： R. J. Serra , Blair D. Walker , Scott M. Evans
CPC分类号： A61B17/3207 , A61B17/320758 , A61B2017/22038 , A61B2017/22084 , A61B2017/320012 , A61B2017/320733 , A61B90/39
摘要： A miniaturized brush and method of making same having a hollow lumen for introducing an agent for dissolving a soft fibrinous obstruction, such as a recently formed thrombus, within a patient's vascular system. The brush has soft, flexible bristles extending outward from the drive shaft distal section, the bristles being sufficiently resilient and dimensioned for enabling compression and passage of the brush out of and back into the distal end of an introducer lumen and to mix into the fibrin of the soft thrombus, yet not damage the vessel wall. The brush assembly is formed of a proximal section comprising an elongated proximal tube and a distal section comprising a distal tube extension, the proximal and distal sections having an aligned lumen and forming a drive shaft or brush body. The brush is formed of brush bristles entrapped between coiled wire turns of a metal having enhanced radiographic imaging characteristics wound about the outer wall of the distal tube extension and distributed in a uniform pattern or in a helical pattern around the circumference of the outer wall to form a helical brush. The distal tube extension may be a continuation of the elongated proximal tube and the coiled wire may be wound about the outer wall of the proximal tube. Alternatively, a separate distal tube extension may be attached to a reinforced proximal tube and the coiled wire may be wound about the distal tube extension and a portion of the distal end of the proximal tube.
摘要翻译： 一种微型电刷及其制造方法，其具有用于将患者血管系统内的诸如最近形成的血栓之类的软性纤维性阻塞物溶解的药剂引入中空管腔。 刷子具有从驱动轴远侧部分向外延伸的柔软且柔韧的刷毛，刷毛具有足够的弹性和尺寸，用于使刷子能够压缩和通过引导器内腔的远端并返回入导管腔的远端，并且混合到纤维蛋白 软血栓，但不会损伤血管壁。 刷组件由包括细长近端管的近端部分和包括远端管延伸部的远侧部分形成，近端部分和远端部分具有对准的内腔并形成驱动轴或刷体。 刷子由夹在卷绕在具有增强的放射线照相成像特性的金属的线圈绕线之间的刷毛形成，该特征缠绕在远端管延伸部的外壁上并以均匀图案或以围绕外壁的圆周的螺旋形图案分布形成 螺旋刷。 远侧管延伸部可以是细长近端管的延伸部，并且线圈绕线可绕近端管的外壁缠绕。 或者，单独的远端管延伸部可以附接到加强的近端管，并且线圈绕线可围绕远端管延伸部和近端管的远端的一部分缠绕。
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公开(公告)号：US5381782A
公开(公告)日：1995-01-17
申请号：US021955
申请日：1993-02-23
申请人： Alan DeLaRama , Larry A. Dial , Richard J. Harp , Thomas L. Hursman , Alfred S. Soria , R. J. Serra , Steve Tarpening
发明人： Alan DeLaRama , Larry A. Dial , Richard J. Harp , Thomas L. Hursman , Alfred S. Soria , R. J. Serra , Steve Tarpening
CPC分类号： A61B1/0056 , A61M25/0133
摘要： A bi-directional endoscope comprising a catheter body having a tubular spring frame attached to and extending axially from the distal end thereof. The spring frame comprises a spring body which includes a tip member positioned on the distal end thereof, and a plurality of relief slots disposed therein for allowing the deflection of the spring frame within a first deflection plane. The relief slots are formed in the spring body in a manner defining first and second longitudinally extending stiffening portions which are oriented substantially diametrically opposite each other therewithin. Extending longitudinally through the catheter body and spring frame is a pair of activation wires which are encased by a pair of support sleeves. The spring frame is deflected by stressing the activation wires by subjecting either of the wires to a tensile force. Stressing the wires as operable to transmit the tensile force from the stressed wire to the tip member thus causing the spring body to deflect in the first deflection plane toward the stressed wire.
摘要翻译： 一种双向内窥镜，其包括导管本体，该导管主体具有连接到其远端并从其远端轴向延伸的管状弹簧框架。 弹簧框架包括弹簧体，弹簧体包括位于其远端上的尖端构件，以及设置在其中的多个释放槽，用于允许弹簧框架在第一偏转平面内的偏转。 释放槽在弹簧体中以限定第一和第二纵向延伸的加强部分的方式形成，该加强部分在其中大体上沿径向相对定向。 纵向延伸穿过导管主体和弹簧框架的是一对激活线，其由一对支撑套筒包围。 弹簧框架通过使任一个电线受到拉力而使激活线受到应力而偏转。 将电线应力可操作以将拉力从受力导线传递到尖端部件，从而使弹簧体在第一偏转平面中朝向应力导线偏转。
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公开(公告)号：US08052718B2
公开(公告)日：2011-11-08
申请号：US10300115
申请日：2002-11-19
申请人： Fred H. Burbank , Michael L. Jones , R. J. Serra , Greig E. Altieri , Jill Uyeno , Yu-Tung Wong , Randy Werneth
发明人： Fred H. Burbank , Michael L. Jones , R. J. Serra , Greig E. Altieri , Jill Uyeno , Yu-Tung Wong , Randy Werneth
IPC分类号： A61B17/00
摘要： A non-invasive blood vessel occlusion device includes a pair of pressure-applying members with opposed tissue-contacting surfaces, a supporting shaft configured to adjust the distance between tissue-contacting surfaces, and at least one sensor for locating a blood vessel disposed on at least one pressure-applying member. Blood vessels may be occluded by indirectly compressing the artery by compressing tissue near to an artery. The occlusion device finds use in, for example, treating uterine disorders and conditions which may be treated by occlusion of the uterine arteries. A uterine artery may be accessed via a body cavity, such as a patient's vagina, and may be occluded by compressing a portion of the vaginal wall around a portion of a uterine artery.
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公开(公告)号：US07651511B2
公开(公告)日：2010-01-26
申请号：US10359386
申请日：2003-02-05
申请人： Fred H. Burbank , Michael L. Jones , R. J. Serra , Greig E. Altieri , Jill Uyeno
发明人： Fred H. Burbank , Michael L. Jones , R. J. Serra , Greig E. Altieri , Jill Uyeno
IPC分类号： A61B17/08
CPC分类号： A61B17/122 , A61B5/026 , A61B5/489 , A61B8/06 , A61B8/12 , A61B2017/2825 , A61B2017/4216 , A61B2090/08021
摘要： The invention provides devices, systems and methods for clamping arteries which are useful in reducing or abolishing blood flow in an artery, and may be used to control hemorrhage following a caesarian delivery. A clamping device embodying features of the invention includes a pair of clamping members with opposed pressure-applying members having facing pressure-applying surfaces, at least one of which is a yieldable pressure-applying surface. The yieldable pressure-applying surface is preferably resilient. The clamping members are configured to adjust the distance between pressure-applying surfaces, and a blood flow sensor is disposed on at least one of the pressure-applying members to aid in locating the target artery and also to monitor blood flow through the artery. The clamping device is particularly suitable for occluding uterine arteries by compressing the broad ligament which contains the uterine artery and which is connected to the patient's uterus with the arterial clamp.
摘要翻译： 本发明提供用于夹紧动脉的装置，系统和方法，其用于减少或消除动脉中的血液流动，并且可用于控制在切片递送之后的出血。 体现本发明特征的夹紧装置包括一对夹紧构件，其具有相对的施加压力的构件，其具有面对的压力施加表面，其中至少一个是可屈服的施加压力表面。 可屈服的施加压力的表面优选是弹性的。 夹紧构件构造成调节压力施加表面之间的距离，并且血压传感器设置在至少一个压力施加构件上，以帮助定位目标动脉并且还监测通过动脉的血流。 夹紧装置特别适用于通过压缩包含子宫动脉的宽韧带并用动脉夹连接到患者的子宫来闭塞子宫动脉。
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