公开(公告)号：US20240239775A1

公开(公告)日：2024-07-18

申请号：US18555470

申请日：2022-04-18

申请人： QINGDAO RUIJI MEDICAL TECHNOLOGY CO., LTD.

发明人： Ning JIAO ,  Xiaodong DOU ,  Tongyu HUO ,  Lingyu SU ,  Xinyi ZHAO ,  Yingjie HUANG ,  Yameng LIU

IPC分类号： C07D409/14 ,  A61K31/438 ,  A61K31/4535 ,  A61K31/496 ,  A61K31/4995 ,  A61K31/551 ,  A61P35/00 ,  C07D405/12 ,  C07D405/14 ,  C07D413/14 ,  C07D471/10 ,  C07D487/08

CPC分类号： C07D409/14 ,  A61K31/438 ,  A61K31/4535 ,  A61K31/496 ,  A61K31/4995 ,  A61K31/551 ,  A61P35/00 ,  C07D405/12 ,  C07D405/14 ,  C07D413/14 ,  C07D471/10 ,  C07D487/08

摘要： The present invention relates to a compound capable of being used as an FXR regulator, a pharmaceutically acceptable salt or ester, a stereoisomer, a tautomer, a geometric isomer, a prodrug, a hydrate, a solvate or a crystalline form thereof, a metabolite form of same, or any combination or mixture of same, and also relates to a preparation method therefor, a pharmaceutical composition thereof and the use thereof.